Caleb Carl Abbott Stokes, MD, PhD

Infectious Disease, Infectious Disease Research

On staff since August 2020

  • Award Name Award Description Awarded By Award Date
    K08 Career Development Award Innate Immunity of Zika Virus Infection in Human Neural Progenitors NIAID 2020 - 2025
  • Other Publications

    • Rodda LB, Netland J, Shehata L, Pruner KB, Morawski PM, Thouvenel C, Takehara KK, Eggenberger J, Hemann EA, Waterman HR, Fahning ML, Chen Y, Rathe J, Stokes C, Wrenn S, Fiala B, Carter LP, Hamerman JA, King NP, Gale M, Campbell DJ, Rawlings D, Pepper M
      Functional SARS-CoV-2-specific immune memory persists after mild COVID-19.
      32817957 medRxiv : the preprint server for health sciences, 2020 Aug. 15 : PMCID:PMC7430599
    • Pepper M, Rodda L, Netland J, Shehata L, Pruner K, Morawski P, Thouvenel C, Takahara K, Eggenberger J, Hemann E, Waterman H, Fahning M, Chen Y, Rathe J, Stokes C, Wrenn S, Fiala B, Carter L, Hamerman J, King N, Gale M, Campbell D, Rawlings D
      Functional SARS-CoV-2-specific immune memory persists after mild COVID-19.
      32818218 Research square, 2020 Aug. 13 : PMCID:PMC7430600
    • Hubbard JM, Böhm UL, Prendergast A, Tseng PB, Newman M, Stokes C, Wyart C
      Intraspinal Sensory Neurons Provide Powerful Inhibition to Motor Circuits Ensuring Postural Control during Locomotion.
      27720623 Current biology : CB, 2016 Nov. 7 : 26(21)2841-2853
    • Böhm UL, Prendergast A, Djenoune L, Nunes Figueiredo S, Gomez J, Stokes C, Kaiser S, Suster M, Kawakami K, Charpentier M, Concordet JP, Rio JP, Del Bene F, Wyart C
      CSF-contacting neurons regulate locomotion by relaying mechanical stimuli to spinal circuits.
      26946992 Nature communications, 2016 March 7 : 710866 PMCID:PMC4786674
    • Fidelin K, Djenoune L, Stokes C, Prendergast A, Gomez J, Baradel A, Del Bene F, Wyart C
      State-Dependent Modulation of Locomotion by GABAergic Spinal Sensory Neurons.
      26752076 Current biology : CB, 2015 Dec. 7 : 25(23)3035-47
    • Stokes CC, Teeter CM, Isaacson JS
      Single dendrite-targeting interneurons generate branch-specific inhibition.
      25505385 Frontiers in neural circuits, 2014 : 8139 PMCID:PMC4243555
    • Stokes CC, Isaacson JS
      From dendrite to soma: dynamic routing of inhibition by complementary interneuron microcircuits in olfactory cortex.
      20696382 Neuron, 2010 Aug. 12 : 67(3)452-65 PMCID:PMC2922014
    • Bjartmar L, Huberman AD, Ullian EM, Rentería RC, Liu X, Xu W, Prezioso J, Susman MW, Stellwagen D, Stokes CC, Cho R, Worley P, Malenka RC, Ball S, Peachey NS, Copenhagen D, Chapman B, Nakamoto M, Barres BA, Perin MS
      Neuronal pentraxins mediate synaptic refinement in the developing visual system.
      16763034 The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006 June 7 : 26(23)6269-81 PMCID:PMC2579897
    • Christopherson KS, Ullian EM, Stokes CC, Mullowney CE, Hell JW, Agah A, Lawler J, Mosher DF, Bornstein P, Barres BA
      Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis.
      15707899 Cell, 2005 Feb. 11 : 120(3)421-33

Overview

Board Certification(s)

Pediatrics

Medical/Professional School

UC - San Diego School of Medicine, La Jolla
Neuroscience, UC - San Diego School of Medicine, La Jolla

Residency

Pediatrics, University of Washington, Seattle

Fellowship

Pediatric Infectious Disease, University of Washington, Seattle

Research Description

I am interested in the mechanisms of brain injury caused by infection or inflammation within the central nervous system (CNS). As a postdoctoral researcher in the laboratory of Dr. Michael Gale, Jr. in the University of Washington Department of Immunology and a Pediatric Infectious Diseases Fellow at UW/Seattle Children’s Hospital I am currently studying the innate immune mechanisms of Zika virus control. My undergraduate and graduate training was in basic and developmental neurosciences; understanding neural circuits and nervous system dysfunction are some of my primary scientific motivations. As an infectious diseases clinician and translational researcher my career goal is to find ways of boosting immune protection or limiting the deleterious consequences of inflammation on neuronal circuits. I am also actively engaged in teaching and mentoring activities through Seattle Children’s hospital and my basic science work. I am firmly committed to building a future research world that includes women and underrepresented minorities.