Alan Aderem, PhD
Alan Aderem, PhD, is a biologist, specializing in immunology and cell biology, with emphasis on the innate immune system, generally regarded as the body’s first line of defense to any pathogen. Aderem co-founded the Institute for Systems Biology (ISB) with Leroy Hood and Ruedi Aebersold in 2000 and served as its director until 2011.
A native of South Africa, Aderem obtained his PhD at the University of Cape Town and completed a postdoctoral fellowship at the Rockefeller University in New York in the laboratory of Dr. Zanvil Cohn. He rose through the ranks at the Rockefeller University, becoming head of the Laboratory of Signal Transduction in 1991. In 1996, he accepted a professorship of immunology and medicine at the University of Washington in Seattle.
- Research Description
Scientists in the Aderem Lab are studying innate responses to HIV, tuberculosis, influenza and other pathogens that significantly impact global health. Our goal is to define the mechanisms that result in a successful immune response to infection or vaccination and identify targets for therapeutic intervention to correct inadequate or dysregulated responses. By integrating systems biology-based “omics” approaches (genomics, transcriptomics, proteomics, metabolomics, etc.), we aim to develop predictive models of the complex interactions that maintain the fine balance between host defense and inflammatory disease. Read more about the Aderem Lab.
- Research Focus Area
Big Data, Computational Biology, Data Analysis, Genomics, Global Health, HIV/AIDS, Host-Pathogen Interaction, Immunology, Infectious Disease, Influenza (Flu), OMICS, Predictive Analytics, Proteomics, Systems Biology, Tuberculosis