Partnership Opportunities

Digital Health Solutions for Chronic Pain

Using technology to treat chronic pain in children and adolescents

Technology Overview

Pain represents an immense clinical problem. Millions of people in the U.S. alone suffer from debilitating chronic pain that results in enormous expenditures on healthcare and lost work productivity. In order to advance the field, reduce this burden, and offer hope to the many patients with chronic pain, innovative strategies are needed to improve access to evidence-based pain self-management. Self-management interventions teach the person how to manage the symptoms, and the physical and psychological consequences and lifestyle changes inherent to living with a chronic condition. Studies in pediatric and adult pain patients demonstrate that self-management strategies can lead to reduced symptoms, improved quality of life, and decreased healthcare utilization. Children with chronic pain are a particularly vulnerable population because access to specialized pain care is more limited and evidence shows that childhood pain often persists or reemerges in adulthood, increasing the importance of effectively managing pain symptoms during childhood.

Tanya PalermoDr. Tonya Palermo

Dr. Palermo is a pediatric psychologist and a pain researcher. She directs the Pediatric Pain & Sleep Innovations Lab that aims to improve the lives of children with pain and their families through developing, evaluating, and disseminating innovative treatments that can be delivered at low cost. Dr. Palermo has developed and tested web- and mobile-based pain management programs in children with chronic headache, abdominal, and musculoskeletal pain. These pain management programs improve access to evidence-based self-management therapies and can empower children to take an active role in managing their condition by providing in the moment access to coping strategies. Her research on Internet interventions for treating pain in children has been pioneering, and she has recently completed the largest pediatric pain clinical trial of Internet-delivered pain intervention, enrolling almost 300 youth and their parents. Her clinical trial demonstrated positive effects of internet-delivered pain intervention for children and their parents. Dr. Palermo is extending her technology-based programs to other populations including children with sickle cell disease and cancer. She is also developing an insomnia management program. Dr. Palermo is looking for partners to develop or evaluate new technologies to treat physical health symptoms in pediatric patients, and to prevent long-term disability.

Stage of Development

  • Pre-commercial and commercial

Partnering Opportunities

  • Collaborative research opportunity
  • Sponsored research agreement
  • Consultation agreement


  1. Palermo TM, Law EF, Fales J, Bromberg MH, Jessen-Fiddick T, Tai G. (2016). Internet-delivered cognitive-behavioral treatment for adolescents with chronic pain and their parents: A randomized controlled multicenter trial. Pain, 157(1): 174-185.
  2. Palermo TM, Zempsky WT, Dampier CD, Lalloo C, Hundert A, Murphy LK, Bakshi N, Stinson JN. (2018). iCanCope with Sickle Cell Pain: Design of a randomized controlled trial of a smartphone and web-based pain self-management program for youth with sickle cell disease. Contemp Clin Trials. 74:88-96. doi: 10.1016/j.cct.2018.10.006.
  3. Palermo TM, de la Vega R, Dudeney J, Murray C, Law E. (2018). Mobile health intervention for self-management of adolescent chronic pain (WebMAP mobile): Protocol for a hybrid effectiveness-implementation cluster randomized controlled trial. Contemp Clin Trials. 74:55-60.
  4. Alberts NM, Law EF, Chen AT, Ritterband LM, Palermo TM. (2018). Treatment engagement in an internet-delivered cognitive behavioral program for pediatric chronic pain. Internet Interv 13:67-72.

Learn More

To learn more about partnering with Seattle Children’s Research Institute on this or other projects, email the Office of Science-Industry Partnerships