Laurie Christine Eldredge, MD, PhD

Laurie Christine Eldredge, MD, PhD

Pulmonary, Bronchopulmonary Dysplasia Program

On staff since July 2015

Children's Title: Co-Director, Bronchopulmonary Dysplasia Program

Academic Title: Assistant Professor

Research Center: Center for Respiratory Biology and Therapeutics

"Dr. Eldredge is enthusiastically committed to providing comprehensive, multidisciplinary, team-based, and family-centered care for her patients with chronic respiratory conditions. Dr. Eldredge seeks to improve care for patients with severe BPD through clinical, translational and basic research. "

  • Biography

    Laurie C. Eldredge, MD, PhD, is an assistant professor in the Department of Pediatrics at the University of Washington School of Medicine and an attending physician at Seattle Children's Hospital. She earned her MD and PhD at Northwestern University Feinberg School of Medicine in Chicago. She completed pediatrics residency training and a fellowship in pediatric pulmonology at the University of Washington.

    • Related Pages

    • Eldredge Lab - Center for Respiratory Biology and Therpeutics

      Eldredge Lab - Center for Respiratory Biology and Therpeutics

      Our mission is to study novel mechanisms of bronchopulmonary dysplasia (BPD) pathogenesis. Three areas of research: development of airway disease in severe BPD; hyperoxia-induced lung injury in vivo (basic mouse model); airway epithelial cell differentiation (mechanistic translational model).

  • Patient Testimonials

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  • Awards and Honors

    Award Name Award Description Awarded By Award Date
    2022 Team Science Ignition Award Establishing Translational Approaches to Evaluate the Role of Fibroblast Growth Factor 2 in Tracheal Patterning and Development Seattle Children's Hospital 2022 - 2024
    NIH K08 Career Development Award NIH Dec 15, 2019 - 2025
    NIH Loan Repayment Awardee NIH Jul 1, 2014 - Jun 30, 2016
    Seattle Childrens Hospital Fellow and Resident Research Day Outstanding Presentation SCH Fellows College 2014
    Outstanding Fellow Teaching Award SCH Pediatric Residents 2014
    Best in Pediatrics Presentation American Thoracic Society 2013

  • Publications

    Other Publications

    • Hammond JD 2nd, Kielt MJ, Conroy S, Lingappan K, Austin ED, Eldredge LC, Truog WE, Abman SH, Nelin LD, Cuevas Guaman M
      "Exploring the Association of Male Sex with Adverse Outcomes in Severe Bronchopulmonary Dysplasia: A Retrospective, Multi-Center Cohort Study".
      37879559 Chest, 2023 Oct 23
    • Kielt MJ, Hatch LD 3rd, Levin JC, Napolitano N, Abman SH, Baker CD, Eldredge LC, Collaco JM, McGrath-Morrow SA, Rose RS, Lai K, Keszler M, Sindelar R, Nelin LD, McKinney RL, BPD Collaborative
      Classifying multicenter approaches to invasive mechanical ventilation for infants with bronchopulmonary dysplasia using hierarchical clustering analysis.
      37265416 Pediatric pulmonology, 2023 Aug. : 58(8)2323-2332
    • Manimtim WM, Agarwal A, Alexiou S, Levin JC, Aoyama B, Austin ED, Bansal M, Bauer SE, Cristea AI, Fierro JL, Garey DM, Hayden LP, Kaslow JA, Miller AN, Moore PE, Nelin LD, Popova AP, Rice JL, Tracy MC, Baker CD, Dawson SK, Eldredge LC, Lai K, Rhein LM, Siddaiah R, Villafranco N, McGrath-Morrow SA, Collaco JM
      Respiratory Outcomes for Ventilator-Dependent Children With Bronchopulmonary Dysplasia.
      37122061 Pediatrics, 2023 May 1 : 151(5) PMCID:PMC10158083
    • Yung D, Jackson EO, Blumenfeld A, Redding G, DiGeronimo R, McGuire JK, Riker M, Tressel W, Berkelhamer S, Eldredge LC
      A multidisciplinary approach to severe bronchopulmonary dysplasia is associated with resolution of pulmonary hypertension.
      37063675 Frontiers in pediatrics, 2023 : 111077422 PMCID:PMC10098720
    • Cristea AI, Tracy MC, Bauer SE, Guaman MC, Welty SE, Baker CD, Bhombal S, Collaco JM, Courtney SE, DiGeronimo RJ, Eldredge LC, Gibbs K, Hayden LP, Keszler M, Lai K, McGrath-Morrow SA, Moore PE, Rose R, Sindelar R, Truog WE, Nelin LD, Abman S, BPD Collaborative
      Approaches to Interdisciplinary Care for Infants with Severe Bronchopulmonary Dysplasia: A Survey of the Bronchopulmonary Dysplasia Collaborative.
      36477715 American journal of perinatology, 2022 Dec 7
    • Eldredge LC, Levin JC, Tracy MC, Cristea AI, Baker CD, Ruminjo JK, Thomson CC
      Summary for Clinicians: Clinical Practice Guidelines for Outpatient Respiratory Management of Infants, Children, and Adolescents with Post-Prematurity Respiratory Disease.
      35239469 Annals of the American Thoracic Society, 2022 June : 19(6)873-879
    • Eldredge LC
      Preventable ATII Proliferation after Hyperoxia: The "Tempo" of Folate Metabolism in the Neonatal Lung.
      35143373 American journal of respiratory cell and molecular biology, 2022 April : 66(4)353-355 PMCID:PMC8990117
    • Cristea AI, Ren CL, Amin R, Eldredge LC, Levin JC, Majmudar PP, May AE, Rose RS, Tracy MC, Watters KF, Allen J, Austin ED, Cataletto ME, Collaco JM, Fleck RJ, Gelfand A, Hayes D Jr, Jones MH, Kun SS, Mandell EW, McGrath-Morrow SA, Panitch HB, Popatia R, Rhein LM, Teper A, Woods JC, Iyer N, Baker CD
      Outpatient Respiratory Management of Infants, Children, and Adolescents with Post-Prematurity Respiratory Disease: An Official American Thoracic Society Clinical Practice Guideline.
      34908518 American journal of respiratory and critical care medicine, 2021 Dec 15 : 204(12)e115-e133 PMCID:PMC8865713
    • McKinney RL, Napolitano N, Levin JJ, Kielt MJ, Abman SH, Guaman MC, Rose RS, Courtney SE, Matlock D, Agarwal A, Leeman KT, Sanlorenzo LA, Sindelar R, Collaco JM, Baker CD, Hannan KE, Douglass M, Eldredge LC, Lai K, McGrath-Morrow SA, Tracy MC, Truog W, Lewis T, Murillo AL, Keszler M, BPD Collaborative.
      Ventilatory Strategies in Infants with Established Severe Bronchopulmonary Dysplasia: A Multicenter Point Prevalence Study.
      34710394 The Journal of pediatrics, 2021 Oct 26
    • Starr MC, Boohaker L, Eldredge LC, Menon S, Griffin R, Mayock DE, Li L, Askenazi D, Hingorani S, Neonatal Kidney Collaborative.
      Acute Kidney Injury and Bronchopulmonary Dysplasia in Premature Neonates Born Less than 32 Weeks' Gestation.
      31777046 American journal of perinatology, 2020 Feb. : 37(3)341-348 PMCID:PMC7409513
    • Starr MC, Boohaker L, Eldredge LC, Menon S, Griffin R, Mayock D, Askenazi D, Hingorani S, Neonatal Kidney Collaborative.
      Acute Kidney Injury is Associated with Poor Lung Outcomes in Infants Born ≥32 Weeks of Gestational Age.
      31739364 American journal of perinatology, 2020 Jan. : 37(2)231-240 PMCID:PMC7408289
    • Eldredge LC, Creasy RS, Presnell S, Debley JS, Juul SE, Mayock DE, Ziegler SF
      Infants with evolving bronchopulmonary dysplasia demonstrate monocyte-specific expression of IL-1 in tracheal aspirates.
      30969811 American journal of physiology. Lung cellular and molecular physiology, 2019 Jul 1 : 317(1)L49-L56
    • Eldredge LC, Creasy RS, Tanaka S, Lai JF, Ziegler SF
      Imbalance of Ly-6Chi and Ly-6Clo Monocytes/Macrophages Worsens Hyperoxia-Induced Lung Injury and Is Rescued by IFN-γ.
      30944158 Journal of immunology (Baltimore, Md. : 1950), 2019 May 1 : 202(9)2772-2781
    • Eldredge LC | Treuting PM | Manicone AM | Ziegler SF | Parks WC | McGuire JK
      CD11b+ Mononuclear Cells Mitigate Hyperoxia-induced Lung Injury in Neonatal Mice.
      American journal of respiratory cell and molecular biology, 2015 Jul 20
    • Eldredge LC | Ramsey BW
      Remarkable progress toward new treatments for cystic fibrosis.
      The Lancet. Respiratory medicine, 2014 Dec. : 2(12)962-4

  • Research Funding

    Grant Title Grantor Amount Award Date
    ATS/ALA Partnered Grant ATS/ALA 2021 - 2023
    K08 Mentored Clinical Scientist Research Career Development Award NIH/NHLBI Dec. 2019 - May 2025
    Parker B. Francis Fellowship in Pulmonary Research Francis Family Foundation 2018 - 2022
    Seattle Children’s Research Institute Center for Clinical and Translational Research Clinical Research Scholars Program (CRSP) Award - Intensive Pathway CCTR 2016 - 2018
    The role of TGFbeta signaling in hyperoxia-induced lung injury and fibrosis. Firland Foundation $20,000 Jul 1, 2015 - Jun 30, 2015

Overview

Board Certification(s)

Pediatrics
Pediatric Pulmonology

Medical/Professional School

Northwestern University, Chicago, IL
Northwestern University, Evanston, IL

Residency

University of Washington School of Medicine, Seattle, WA

Fellowship

University of Washington School of Medicine, Seattle, WA

Clinical Interests

Bronchopulmonary Dysplasia

Lung Development

Management of Chronic Respiratory Failure

Research Description

Dr. Eldredge is a physician-scientist at the Seattle Children's Center for Respiratory Biology and Therapeutics. Her primary research focus is in the pathogenesis of bronchopulmonary dysplasia, also known as chronic lung disease of prematurity. Specifically, she is working to understand the roles of monocytes and epithelial cells in the development of this inflammatory lung disease.