Anne V Hing, MD

Anne V Hing, MD

Craniofacial Center, Genetics, Craniofacial Genetics Clinic

On staff since March 2000

Academic Title: Professor

Research Center: Center for Developmental Biology and Regenerative Medicine

  • Biography

    Anne V. Hing, MD, is attending physician at Seattle Children's Hospital, professor in the Department of Pediatrics at the University of Washington School of Medicine, and adjunct faculty member in the Division of Medical Genetics. Her clinical interests include the diagnosis and management of infants, children, and adolescents with craniofacial and genetic conditions.

    Dr. Hing works in the Craniofacial and Craniofacial Genetics Clinics and also serves as a genetics consultant in outreach clinics throughout the state of Washington. She coordinates the Craniofacial resident elective (and selective) rotation and provides bedside teaching for medical students and residents. She is program director of the Craniofacial Medicine fellowship and coordinates the annual multidisciplinary Craniofacial Center Educational Retreat.

    • Related Pages

    • Hing Studies

      Dr. Anne V. Hing investigates the genetic causes of craniofacial disorders and specializes in recruiting patients for studies.

  • Patient Testimonials
  • Awards and Honors
    Award Name Award Description Awarded By Award Date
    Richard A. Molteni Award Seattle Children's Hospital 2012
    Poncin Foundation Scholarship 2001
    Edward Mallinckrodt Jr. Foundation Scholarship 1995
    George F. Gill Prize in Pediatrics 1985
    Alpha Omega Alpha, Medical Honor Society 1985
    Dr. Margaret G. Smith Award for Outstanding Achievement by a Woman Medical Student in the First Two Years of Medical School, Scholarship Achievement Citation American Medical Woman's Association, Inc. 1983
    Edmund V. Cowdry Prize in Histology 1982
    Kappa Alpha Pi-Scholastic Honor Society 1981
  • Publications

    Other Publications

    • Wenger TL, Dahl J, Bhoj EJ, Rosen A, McDonald-McGinn D, Zackai E, Jacobs I, Heike CL, Hing A, Santani A, Inglis AF, Sie KC, Cunningham M, Perkins J
      Tracheal cartilaginous sleeves in children with syndromic craniosynostosis.
      27228464 Genetics in medicine : official journal of the American College of Medical Genetics, 2016 May 26
    • Wieczorek D, Newman WG, Wieland T, Berulava T, Kaffe M, Falkenstein D, Beetz C, Graf E, Schwarzmayr T, Douzgou S, Clayton-Smith J, Daly SB, Williams SG, Bhaskar SS, Urquhart JE, Anderson B, O'Sullivan J, Boute O, Gundlach J, Czeschik JC, van Essen AJ, Hazan F, Park S, Hing A, Kuechler A, Lohmann DR, Ludwig KU, Mangold E, Steenpaß L, Zeschnigk M, Lemke JR, Lourenco CM, Hehr U, Prott EC, Waldenberger M, Böhmer AC, Horsthemke B, O'Keefe RT, Meitinger T, Burn J, Lüdecke HJ, Strom TM
      Compound Heterozygosity of Low-Frequency Promoter Deletions and Rare Loss-of-Function Mutations in TXNL4A Causes Burn-McKeown Syndrome.
      25434003 American journal of human genetics, 2014 Dec 4 : 95(6)698-707 PMCID:PMC4259969
    • Smith JD, Hing AV, Clarke CM, Johnson NM, Perez FA, Park SS, Horst JA, Mecham B, Maves L, Nickerson DA, University of Washington Center for Mendelian Genomics, Cunningham ML
      Exome sequencing identifies a recurrent de novo ZSWIM6 mutation associated with acromelic frontonasal dysostosis.
      25105228 American journal of human genetics, 2014 Aug 7 : 95(2)235-40 PMCID:PMC4129399
    • Evans KN, Gruss JS, Khanna PC, Cunningham ML, Cox TC, Hing AV
      Oculoauriculofrontonasal syndrome: case series revealing new bony nasal anomalies in an old syndrome.
      23637006 American journal of medical genetics. Part A, 2013 June : 161A(6)1345-53
    • Luquetti DV, Hing AV, Rieder MJ, Nickerson DA, Turner EH, Smith J, Park S, Cunningham ML
      "Mandibulofacial dysostosis with microcephaly" caused by EFTUD2 mutations: expanding the phenotype.
      23239648 American journal of medical genetics. Part A, 2013 Jan. : 161A(1)108-13 PMCID:PMC3535578
    • Rieder MJ, Green GE, Park SS, Stamper BD, Gordon CT, Johnson JM, Cunniff CM, Smith JD, Emery SB, Lyonnet S, Amiel J, Holder M, Heggie AA, Bamshad MJ, Nickerson DA, Cox TC, Hing AV, Horst JA, Cunningham ML
      A human homeotic transformation resulting from mutations in PLCB4 and GNAI3 causes auriculocondylar syndrome.
      22560091 American journal of human genetics, 2012 May 4 : 90(5)907-14 PMCID:PMC3376493
    • Hing AV, Mefford HC, Cunningham ML
      New developments in genetic diagnosis: implications for the craniofacial surgeon.
      22337411 The Journal of craniofacial surgery, 2012 Jan. : 23(1)212-6
    • Cunningham ML, Horst JA, Rieder MJ, Hing AV, Stanaway IB, Park SS, Samudrala R, Speltz ML
      IGF1R variants associated with isolated single suture craniosynostosis.
      21204214 American journal of medical genetics. Part A, 2011 Jan. : 155A(1)91-7 PMCID:PMC3059230
    • Mefford HC, Shafer N, Antonacci F, Tsai JM, Park SS, Hing AV, Rieder MJ, Smyth MD, Speltz ML, Eichler EE, Cunningham ML
      Copy number variation analysis in single-suture craniosynostosis: multiple rare variants including RUNX2 duplication in two cousins with metopic craniosynostosis.
      20683987 American journal of medical genetics. Part A, 2010 Sept. : 2203-10
    • Bachmann-Gagescu R, Mefford HC, Cowan C, Glew GM, Hing AV, Wallace S, Bader PI, Hamati A, Reitnauer PJ, Smith R, Stockton DW, Muhle H, Helbig I, Eichler EE, Ballif BC, Rosenfeld J, Tsuchiya KD
      Recurrent 200-kb deletions of 16p11.2 that include the SH2B1 gene are associated with developmental delay and obesity.
      20808231 Genetics in medicine : official journal of the American College of Medical Genetics, 2010 Aug 30
    • Heike CL, Cunningham ML, Hing AV, Stuhaug E, Starr JR
      Picture perfect? Reliability of craniofacial anthropometry using three-dimensional digital stereophotogrammetry.
      19935311 Plastic and reconstructive surgery, 2009 Oct. : 1261-72
    • Hing AV, Click ES, Holder U, Seto ML, Vessey K, Gruss J, Hopper R, Cunningham ML
      Bilateral lambdoid and sagittal synostosis (BLSS): a unique craniosynostosis syndrome or predictable craniofacial phenotype?
      19396832 American journal of medical genetics. Part A, 2009 May : 1024-32
    • Suzuki S, Marazita ML, Cooper ME, Miwa N, Hing A, Jugessur A, Natsume N, Shimozato K, Ohbayashi N, Suzuki Y, Niimi T, Minami K, Yamamoto M, Altannamar TJ, Erkhembaatar T, Furukawa H, Daack-Hirsch S, L'heureux J, Brandon CA, Weinberg SM, Neiswanger K, Deleyiannis FW, de Salamanca JE, Vieira AR, Lidral AC, Martin JF, Murray JC
      Mutations in BMP4 are associated with subepithelial, microform, and overt cleft lip.
      19249007 American journal of human genetics, 2009 March : 84(3)406-11 PMCID:PMC2667991
    • Jenkins ZA, van Kogelenberg M, Morgan T, Jeffs A, Fukuzawa R, Pearl E, Thaller C, Hing AV, Porteous ME, Garcia-Miñaur S, Bohring A, Lacombe D, Stewart F, Fiskerstrand T, Bindoff L, Berland S, Adès LC, Tchan M, David A, Wilson LC, Hennekam RC, Donnai D, Mansour S, Cormier-Daire V, Robertson SP
      Germline mutations in WTX cause a sclerosing skeletal dysplasia but do not predispose to tumorigenesis.
      19079258 Nature genetics, 2009 Jan. : 95-100
    • Tsuchiya KD, Opheim KE, Hannibal MC, Hing AV, Glass IA, Raff ML, Norwood T, Torchia BA
      Unexpected structural complexity of supernumerary marker chromosomes characterized by microarray comparative genomic hybridization.
      18471320 Molecular Cytogenetics, 2008 Apr 21 : 7
    • Sanchez-Lara PA, Graham JM Jr, Hing AV, Lee J, Cunningham M
      The morphogenesis of wormian bones: a study of craniosynostosis and purposeful cranial deformation.
      18000970 American journal of medical genetics. Part A, 2007 Dec 15 : 3243-51
    • Heike CL, Avellino AM, Mirza SK, Kifle Y, Perkins J, Sze R, Egbert M, Hing AV
      Sleep disturbances in 22q11.2 deletion syndrome: a case with obstructive and central sleep apnea.
      17477750 The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2007 May : 340-6
    • Cunningham ML, Seto ML, Ratisoontorn C, Heike CL, Hing AV
      Syndromic craniosynostosis: from history to hydrogen bonds.
      17552943 Orthodontics & craniofacial research, 2007 May : 67-81
    • Seto ML, Hing AV, Chang J, Hu M, Kapp-Simon KA, Patel PK, Burton BK, Kane AA, Smyth MD, Hopper R, Ellenbogen RG, Stevenson K, Speltz ML, Cunningham ML
      Isolated sagittal and coronal craniosynostosis associated with TWIST box mutations.
      17343269 American journal of medical genetics. Part A, 2007 Apr 1 : 678-86
    • Hing AV, Leblond C, Sze RW, Starr JR, Monks S, Parisi MA
      A novel oculo-oto-facial dysplasia in a Native Alaskan community with autosomal recessive inheritance.
      16523509 American journal of medical genetics. Part A, 2006 Apr 15 : 804-12
    • Ruiz-Correa S, Sze RW, Starr JR, Lin HT, Speltz ML, Cunningham ML, Hing AV
      New scaphocephaly severity indices of sagittal craniosynostosis: a comparative study with cranial index quantifications.
      16526927 The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2006 March : 211-21
    • Cunningham ML, Seto ML, Hing AV, Bull MJ, Hopkin RJ, Leppig KA
      Cleidocranial dysplasia with severe parietal bone dysplasia: C-terminal RUNX2 mutations.
      16463420 Birth defects research. Part A, Clinical and molecular teratology, 2006 Feb. : 78-85
    • Sze RW, Hopper RA, Ghioni V, Gruss JS, Ellenbogen RG, King D, Hing AV, Cunningham ML
      MDCT diagnosis of the child with posterior plagiocephaly.
      16247160 AJR. American journal of roentgenology, 2005 Nov. : 1342-6
    • Hing AV, Syed N, Cunningham ML
      Familial acromelic frontonasal dysostosis: autosomal dominant inheritance with reduced penetrance.
      15264282 American journal of medical genetics. Part A, 2004 Aug 1 : 374-82


Board Certification(s)

Clinical Genetics and Genomics (MD)

Medical/Professional School

Washington University School of Medicine, Saint Louis, MO


Washington University School of Medicine, Saint Louis, MO

Research Focus Area