Profile

Michael McMullan, MD

Michael McMullan, MD

Cardiac Surgery, Transplantation

On staff since September 2007

Children's Title: Surgical Director, Cardiac Transplant; Director, Mechanical Cardiac Support and ECLS Services

Academic Title: Associate Professor of Surgery

Research Center: Center for Developmental Therapeutics

"I was drawn to pediatric cardiac surgery by the opportunity to make a very real difference in the lives of children with difficult medical problems. My greatest reward is helping these children live healthy, happy lives. We are privileged to have access to cutting-edge medical technology in this country. I work every day to apply this technology in ways that improve the safety and quality of life of my patients."

  • Michael McMullan, MD, is as an attending pediatric cardiothoracic surgeon at Seattle Children's Hospital and an Associate Professor of Surgery at the University School of Medicine. He is Director of Mechanical Cardiac Support and ECLS Services.

    He received his MD from the University of Texas Southwestern Medical School and completed residencies and fellowships at the Texas Heart Institute, the University of Washington School of Medicine, the University of California San Francisco, and the Royal Childrens Hospital in Melbourne, Australia. His clinical and research interests include neonatal heart surgery and improving patient safety during mechanical cardiopulmonary support.

    • jason Olympia, wa 02.28.16

      A miracle worker. Spent over 5 hours with my daughter in open heart surgery to fix a heart defect. She is going on 2 now and is perfect. I'd really like to express how indebted I am to you. I'd also really like to bring her by the hospital for her birthday. The outreach program hasn't responded to my inquires. Your awesome, keep doing what you do. You and your peers literally have the largest impact on people's lives. I've never been more desperate and more grateful than the hours my daughter was in surgery.

    • Stefani Olympia, Washington 07.24.13

      Dr. Michael McMullan, you're an amazing surgeon! If it weren't for you I probably wouldn't be here today! You fixed up my heart! I finally graduated high school and now I'm doing an Insanity workout. It's one of the hardest workouts! Thanks to you my heart doesn't skip beats anymore! I'm focusing on exercising my heart and eating healthy! I'm suppose to get another surgery in a year or so and I'm hoping I get you to fix it up again! I feel a lot better and you can definitely tell a difference! Thanks to you, you saved my life and now I can live a full and happy life :)

    • Kim Spokane wa 06.17.13

      Dr. McMullan happened to be working the day our son Kyle received his new heart. We will be forever grateful that he was part of our son's gift of life. Thank you for following us through a very tough journey he is 16 now and doing amazing.

    • Carrie Kennewick, Wa 02.22.11

      Dr.McMullan is a wonderful surgeon as well as being wonderful with our family. He can really put your mind at ease as a parent, and that is a tough thing to do. Thank you Dr. McMullan.

    • Maribel Burien,WA 02.11.11

      Two hours after my son was born a Doctor said that only 1% with the same heart condition survive but once we were in children's Dr. McMullan came to the room and explain my son condition and the steps to fix my baby's heart. Thanks to this Dr. I had a reason to look forward in life. My son is now 3 years old and doing just great.

  • Award Name Award Description Awarded By Award Date
    Seattle's Top Doc Seattle Met Magazine 2013
    Seattle Magazine Top Doctor Seattle Magazine 2013
    Norman Shumway Award for Best Paper 37th Annual Meeting of the Western Thoracic Surgical Association (Senior Author) 2011
    Society of Thoracic Surgeons Clinical Research Training Scholarship 2004
    Award for Most Outstanding Scientific Paper International Symposium on Pediatric Cardiac Intensive Care, Miami 1996
    Sigma Alpha Mu Samuel Miller Award for Scientific Research Award 1993
    Sarnoff Cardiovascular Research Foundation Research Award 1992
    Aaron Hartman Award for Outstanding Student in Psychology Tulane University 1989
    • Hong BJ, Delaney M, Guynes A, Warner P, McMullan DM, Kemna MS, Boucek RJ, Law YM
      Human leukocyte antigen sensitization in pediatric patients exposed to mechanical circulatory support.
      24469294 ASAIO journal (American Society for Artificial Internal Organs : 1992) , 2014 May : 60(3)317-21
    • Smith KM, McMullan DM, Bratton SL, Rycus P, Kinsella JP, Brogan TV
      Is age at initiation of extracorporeal life support associated with mortality and intraventricular hemorrhage in neonates with respiratory failure?
      24603452 Journal of perinatology : official journal of the California Perinatal Association , 2014 May : 34(5)386-91
    • Mesher AL, McMullan DM
      Extracorporeal life support for the neonatal cardiac patient: outcomes and new directions.
      24580765 Seminars in perinatology , 2014 Mar. : 38(2)97-103
    • Mesher AL, Brogan TV, Kim K, Chen JM, McMullan DM
      Prematurity negatively impacts cardiac extracorporeal life support survival
      Journal of Surgical Research , 2014 : 186(2)600
    • Bannister L, Blume B, McMullan DM, Petropoulos A, White-Williams C, McMullan DM
      Health Care Delivery
      In Kirk R, Dipchand AI, Rosenthal DN, Kirklin JK (eds): ISHLT Monograph Series Volume 8: ISHLT Guidelines for the Management of Pediatric Heart Failure, Elsevier, Philadelphia , 2014
    • Karamlou T, McMullan DM, Cohen GA
      Truncus Arteriosus
      In Baumgartner WA, Yuh DD, Vricella LA (eds): The John Hopkins Textbook of Cardiothoracic Surgery, 2nd Ed, McGraw-Hill, New York , 2014
    • Karamlou T, McMullan DM, Baden H, Jeffries H, Cohen GA
      Extracorporeal Membrane Oxygenation in Pediatric Cardiac Care
      In Baumgartner WA, Yuh Dd, Vricella LA (eds): The John Hopkins Textbook of Cardiothoracic Surgery, 2nd Ed, McGraw-Hill, New York , 2014
    • McMullan DM, Pearl J
      New and Developing Technologies for Ventricular Assistance
      In da Cruz EM, Ivy DD, Hraska V, Jagger J (eds): Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care, Springer-Verlag, London , 2014
    • McMullan DM, Thiagarajan RR, Smith KM, Rycus PT, Brogan TV
      Extracorporeal cardiopulmonary resuscitation outcomes in term and premature neonates*.
      24141660 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2014 Jan. : 15(1)e9-e16
    • Karamlou T, Welke KF, McMullan DM, Cohen GA, Gelow J, Tibayan FA, Mudd JM, Slater MS, Song HK
      Combined heart-kidney transplant improves post-transplant survival compared with isolated heart transplant in recipients with reduced glomerular filtration rate: Analysis of 593 combined heart-kidney transplants from the United Network Organ Sharing Database.
      24183335 The Journal of thoracic and cardiovascular surgery , 2014 Jan. : 147(1)456-461.e1
    • Symons JM, McMahon MW, Karamlou T, Parrish AR, McMullan DM
      Continuous renal replacement therapy with an automated monitor is superior to a free-flow system during extracorporeal life support.
      23965637 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2013 Nov. : 14(9)e404-8
    • MacIver RH, Permut LC, McMullan DM
      Downsized Contegra graft as a right ventricle-to-pulmonary artery conduit in the setting of mediastinitis.
      23992706 The Annals of thoracic surgery , 2013 Sept. : 96(3)1077-8
    • Delaney M, Axdorff-Dickey RL, Crockett GI, Falconer AL, Levario MJ, McMullan DM
      Risk of extracorporeal life support circuit-related hyperkalemia is reduced by prebypass ultrafiltration.
      23823207 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2013 July : 14(6)e263-7
    • MacLaren G, Dodge-Khatami A, Dalton HJ, Writing Committee, MacLaren G, Dodge-Khatami A, Dalton HJ, Adachi I, Almodovar M, Annich G, Bartlett R, Bronicki R, Brown K, Butt W, Cooper D, Demuth M, D'Udekem Y, Fraser C, Guerguerian AM, Heard M, Horton S, Ichord R, Jaquiss R, Laussen P, Lequier L, Lou S, Marino B, McMullan M, Ogino M, Peek G, Pretre R, Rodefeld M, Schmidt A, Schwartz S, Shekerdemian L, Shime N, Sivarajan B, Stiller B, Thiagarajan R
      Joint statement on mechanical circulatory support in children: a consensus review from the Pediatric Cardiac Intensive Care Society and Extracorporeal Life Support Organization.
      23735979 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2013 June : 14(5 Suppl 1)S1-2
    • Lequier L, Horton SB, McMullan DM, Bartlett RH
      Extracorporeal membrane oxygenation circuitry.
      23735989 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2013 June : 14(5 Suppl 1)S7-12
    • Doorenbos AZ, Starks H, Bourget E, McMullan DM, Lewis-Newby M, Rue TC, Lindhorst T, Aisenberg E, Oman N, Curtis JR, Hays R, Seattle Ethics in ECLS (SEE) Consortium, Clark JD, Baden HP, Brogan TV, Di Gennaro JL, Mazor R, Roberts JS, Turnbull J, Wilfond BS
      Examining palliative care team involvement in automatic consultations for children on extracorporeal life support in the pediatric intensive care unit.
      23540309 Journal of palliative medicine , 2013 May : 16(5)492-5 PMCID: PMC3705963
    • McMullan DM
      Expanding the availability of extracorporeal cardiopulmonary resuscitation.
      23382440 Pediatrics , 2013 Mar. : 131(3)e934-8
    • Karamlou T, Vafaeezadeh M, Parrish AM, Cohen GA, Welke KF, Permut L, McMullan DM
      Increased extracorporeal membrane oxygenation center case volume is associated with improved extracorporeal membrane oxygenation survival among pediatric patients.
      23246046 The Journal of thoracic and cardiovascular surgery , 2013 Feb. : 145(2)470-5
    • Law S, Brogan TV, Law Y, McMullan DM
      Age and era-based survival differences in thoracic transplantation patients who require ECMO
      Journal of Heart and Lung Transplantation , 2013 : 32(4S)S25
    • Baileselassie B, Allen J, Soriano B, Bhat A, Boucek R, Kemna M, Law S, Albers E, McMullan DM, Lay Y
      Correlation of B-type natriuretic peptide (BNP) with echocardiographic and catheterization parameters in pediatric heart recipients
      Journal of Heart and Lung Transplantation , 2013 : 32(4S)S241
    • Ideen C, Albers E, Law Y, Warner P, McMullan DM, Permut L, Kemna M
      Effect of initial surgical palliation on HLA sensitization and outcomes in children transplanted for hypoplastic left heart syndrome (HLHS)
      Journal of Heart and Lung Transplantation , 2013 : 32(4S)S652
    • Subramanian S, Vafaeezadeh M, Parrish AR, McMullan DM
      Comparison of wire-reinforced and non-wire-reinforced dual-lumen catheters for venovenous ECMO in neonates and infants.
      23263340 ASAIO journal (American Society for Artificial Internal Organs : 1992) , 2013 Jan. : 59(1)81-5
    • McMullan DM
      Should intravenous immunoglobulin be given to patients with postoperative chylothorax?.
      22955461 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2012 Sept. : 13(5)599-600
    • McMullan DM
      Clinical management of pediatric tracheo-bronchomalacia.
      21897163 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2011 Sept. : 12(5)599-600
    • Salerno JC, Seslar SP, Chun TU, Vafaeezadeh M, Parrish AR, Permut LC, Cohen GA, McMullan DM
      Predictors of ECMO support in infants with tachycardia-induced cardiomyopathy.
      21448617 Pediatric cardiology , 2011 Aug. : 32(6)754-8
    • Hermes HM, Cohen GA, Mehrotra AK, McMullan DM, Permut LC, Goodwin S, Stevens AM
      Association of thymectomy with infection following congenital heart surgery.
      23803985 World journal for pediatric and congenital heart surgery , 2011 July : 2(3)351-8
    • McMullan DM, Emmert JA, Permut LC, Mazor RL, Jeffries HE, Parrish AR, Baden HP, Cohen GA
      Minimizing bleeding associated with mechanical circulatory support following pediatric heart surgery.
      20801051 European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery , 2011 Mar. : 39(3)392-7
    • Subramanian S, Clark JD, Jeffries HE, McMullan DM
      Novel pH1N1 viral cardiomyopathy requiring veno-venous extracorporeal membrane oxygenation.
      20453697 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2010 Nov. : 11(6)714-7
    • McMullan DM
      Relative risks of recombinant factor VII.
      19741450 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2009 Sept. : 10(5)604-5
    • Linam J, Permut LC, McMullan DM, Morscheck AR, Cohen GA
      The Konno procedure for left ventricular outflow tract obstruction in pediatric patients
      Journal of Investigative Medicine , 2009 : 57(1)481
    • McMullan DM, Reddy VM, Gottliebson WM, Silverman NH, Perry SB, Chan F, Hanley FL, Riemer RK
      Morphological studies of pulmonary arteriovenous shunting in a lamb model of superior cavopulmonary anastomosis.
      18043856 Pediatric cardiology , 2008 July : 29(4)706-12 PMCID: PMC2970565
    • Oppido G, Davies B, McMullan DM, Cochrane AD, Cheung MM, d'Udekem Y, Brizard CP
      Surgical treatment of congenital mitral valve disease: midterm results of a repair-oriented policy.
      18544378 The Journal of thoracic and cardiovascular surgery , 2008 June : 135(6)1313-20; discussion 1320-1
    • Hoang TK, Shekerdemian LS, McMullan DM, Wilkinson JL
      Characteristic of the Young Infant with Congenital Heart Disease
      In Tran H, Le TP, McMullan, DM, Wilkinson JL (eds): Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developted Countries, Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City , 2008
    • Truong U, McMullan DM
      Percutaneous Catheter-Based Interventions
      In Tran H, le TP, McMullan, DM, Wilkinson JL (eds): Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developed Countries, Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City , 2008
    • in Tran H, Le TP, McMullan, DM, Wilkinson JL (eds): Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developed Countries, Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City
      Surgical Treatment of Congenital Heart Disease in Developed Countries
      In Tran H, Le TP, McMullan, DM, Wilkinson JL (eds): Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developed Countries, Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City , 2008
    • Hoang TK, Vu MP, Tran TH, McMullan DM, Shekerdemian LS, Wilkinson JL
      The Burden of Congenital Heart Disease
      In Tran H, Le TP, McMullan, DM, Wilkinson JL (eds): Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developed Countries, Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City , 2008
    • Tran H, Le TP, McMullan, DM, Wilkinson JL (eds)
      Diagnosis and Management of Congenital Heart Disease in the Young Infant in Vietnam and Developed Countries
      Nha Xuat Ban Y Hoc Publishing, Ho Chi Minh City , 2008
    • McMullan DM, Oppido G, Davies B, Kawahira Y, Cochrane AD, d'Udekem d'Acoz Y, Penny DJ, Brizard CP
      Surgical strategy for the bicuspid aortic valve: tricuspidization with cusp extension versus pulmonary autograft.
      17599491 The Journal of thoracic and cardiovascular surgery , 2007 July : 134(1)90-8
    • McMullan DM, Moulick A, Jonas RA
      Late embolization of Amplatzer patent ductus arteriosus occlusion device with thoracic aorta embedment.
      17307488 The Annals of thoracic surgery , 2007 Mar. : 83(3)1177-9
    • McMullan DM, Elliot MJ, Cohen GA
      ECMO for Infants and Children
      In Gravlee GP, Davis RF, Stammers AH, Ungerleider RM (eds): Cardiopulmonary Bypass Principles and Practice, 3rd ed, Lippincott Williams and Wilkins, Philadelphia , 2007
    • McMullan DM, Cohen GA
      Truncus Arteriosus
      In Baumgartner WA, Yuh DD, Vricella LA (eds): The John Hopkins Manual of Cardiothoracic Surgery, McGraw-Hill, New York , 2007
    • McMullan DM, Dalton HJ
      Extracorporeal support in hypoplastic left heart syndrome: who and why?
      16829830 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2006 July : 7(4)390-1
    • McMullan DM, Oppido G, Alphonso N, Cochrane AD, d'Acoz Yd, Brizard CP
      Evaluation of downsized homograft conduits for right ventricle-to-pulmonary artery reconstruction.
      16798304 The Journal of thoracic and cardiovascular surgery , 2006 July : 132(1)66-71
    • Parry AJ, McMullan DM, Yelich S, Hanley FL
      Profile of serum S100beta levels during maturation in fetal and neonatal sheep.
      16586228 American journal of perinatology , 2006 Apr, : 23(3)153-8
    • McMullan DM
      Overview of the Thoracic Surgery Residents Association
      Annals of Thoracic Surgery , 2006 : 81(3)1180
    • McMullan DM, Cohen GA
      Images in clinical medicine. Radiographic evidence linking tobacco use and lung cancer.
      16436771 The New England journal of medicine , 2006 Jan. : 354(4)397
    • McMullan DM, McBride M, Livesay JJ, Dougherty KG, Krajcer Z
      Celiac artery aneurysm: a case report.
      16878636 Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital , 2006 : 33(2)235-40 PMCID: PMC1524716
    • DeLaRosa J, Thourani VH, Wheatley GH 3rd, McMullan DM, Karamanoukian RL, Greene MG, Morales DL
      Impact of resident duty hour standards on cardiothoracic residents and program directors.
      16242419 The Annals of thoracic surgery , 2005 Nov. : 80(5)1569-71
    • Alphonso N, Taib R, Guerrero R, McMullan DM, d'Udekem d'Acoz YAC, Penny D, Brizard CP
      Elective rapid re-training of the deconditioned left ventricle after the arterial switch operation with a left ventricular assist device
      Journal of Thoracic and Cardiovascular Surgery , 2005 : 129(3)715
    • McMullan DM, Hanley FL, Cohen GA, Portman MA, Riemer RK
      Pulmonary arteriovenous shunting in the normal fetal lung.
      15464334 Journal of the American College of Cardiology , 2004 Oct. : 44(7)1497-500
    • Gaissert HA, Casale AS, Creswell LL, Ferguson TB Jr, Fullerton DA, Kernstine KH, McMullan DM, Ring WS, Putnam JB Jr, Society of Thoracic Surgeons Workforce on Clinical Trials
      Mentoring clinical trials in thoracic and cardiovascular surgery: a new role for the Society of Thoracic Surgeons.
      15111218 The Annals of thoracic surgery , 2004 May : 77(5)1874-5
    • McMullan DM, Hanley FL, Riemer RK
      A method for selectively limiting lumen diameter in corrosion casting.
      15121445 Microvascular research , 2004 May : 67(3)215-7
    • DeLaRosa J, Thourani VH, Wheatley GH, McMullan DM, Karamanoukian RL, Morales DL
      The impact of resident duty hour standards: a survey of cardiothoracic surgery residents and program directors
      Annals of Thoracic Surgery , 2004 : 78(6)2227
    • McMullan DM, Walsh GL
      Pleural Effusions
      In Yang SC, Cameron DE (eds): Current Therapy of Thoracic and Cardiovascular Surgery, Harcourt, Phladelphia , 2004
    • McMullan DM, Wood DE
      Pulmonary carcinoid tumors.
      12973707 Seminars in thoracic and cardiovascular surgery , 2003 July : 15(3)289-300
    • McMullan DM, Wilansky S, Frazier OH
      Ventricular fibrillation in a heterotopic heart transplant recipient.
      12607690 The Annals of thoracic surgery , 2003 Feb. : 75(2)598
    • Malhotra SP, Reddy VM, Thelitz S, He YP, McMullan DM, Hanley FL, Riemer RK
      The role of oxidative stress in the development of pulmonary arteriovenous malformations after cavopulmonary anastomosis.
      12202863 The Journal of thoracic and cardiovascular surgery , 2002 Sept. : 124(3)479-85
    • Black SM, Bekker JM, McMullan DM, Parry AJ, Ovadia B, Reinhartz O, Lakshminrushimha S, Mata-Greenwood E, Steinhorn RH, Fineman JR
      Alterations in nitric oxide production in 8-week-old lambs with increased pulmonary blood flow.
      12149501 Pediatric research , 2002 Aug. : 52(2)233-44
    • McMullan DM, Patel V, Radovancevic B, Hochman FL, Frazier OH
      Cytomegalovirus cholecystitis in a heart transplant recipient.
      12072337 Transplantation proceedings , 2002 June : 34(4)1271-2
    • Gutierrez JA, Parry AJ, McMullan DM, Chapin CJ, Fineman JR
      Decreased surfactant proteins in lambs with pulmonary hypertension secondary to increased blood flow.
      11597919 American journal of physiology. Lung cellular and molecular physiology , 2001 Nov. : 281(5)L1264-70
    • Wedgwood S, McMullan DM, Bekker JM, Fineman JR, Black SM
      Role for endothelin-1-induced superoxide and peroxynitrite production in rebound pulmonary hypertension associated with inhaled nitric oxide therapy.
      11509453 Circulation research , 2001 Aug. : 89(4)357-64
    • McMullan DM, Bekker JM, Johengen MJ, Hendricks-Munoz K, Gerrets R, Black SM, Fineman JR
      Inhaled nitric oxide-induced rebound pulmonary hypertension: role for endothelin-1.
      11158977 American journal of physiology. Heart and circulatory physiology , 2001 Feb. : 280(2)H777-85
    • Parry AJ, McMullan DM, Yelich S, Riemer RK, Hanley FL
      The impact of fetal exposure on hemodynamics, white cell activation, and the stress response
      Pediatric Research , 2001 : 49(4 Part 2)56a, I1
    • Gottliebson WM, Cai L, McMullan DM, Brook MM, Schiller NB, Glantz SA
      Cardiac chamber interaction and the pericardium
      Circulation , 2001 : 104(17)II-564
    • McMullan DM, Radovaneevi B, Jackow CM, Frazier OH, Duvic M
      Cutaneous T-cell lymphoma in a cardiac transplant recipient.
      11678256 Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital , 2001 : 28(3)203-7 PMCID: PMC101179
    • Beyer EA, McMullan DM, Delgado R, Gregoric I, Radovancevic B, Frazier OH
      Normalization of native heart function years after heterotopic transplantation.
      11093512 The Annals of thoracic surgery , 2000 Nov. : 70(5)1690-1; discussion 1691-2
    • McMullan DM, Bekker JM, Parry AJ, Johengen MJ, Kon A, Heidersbach RS, Black SM, Fineman JR
      Alterations in endogenous nitric oxide production after cardiopulmonary bypass in lambs with normal and increased pulmonary blood flow.
      11082382 Circulation , 2000 Nov. : 102(19 Suppl 3)III172-8
    • McMullan DM, Beyer EA, Gregoric I, Radovancevic B, Frazier OH
      Left ventricular reduction in a Jehovah's Witness.
      11016342 The Annals of thoracic surgery , 2000 Sept. : 70(3)958-60; discussion 960-1
    • Wedgwood S, McMullan DM, Bekker JM, Fineman, Black SM
      ETA receptor blockade preserves NOS activity during inhaled NO therapy: a role for ET-1-induced superoxide production
      Circulation , 2000 : 102(18)II-169
    • Michael McMullan, MD, Malhotra SP, Reinhartz O, McMullan DM, Thelitz S, Bekker JM, Johengen MJ, Ovadia B, He YP, Riemer RK, Fineman JR
      Alterations in the angiotensin system induced by increased pulmonary blood flow in lambs with pulmonary hypertension
      Critical Care Medicine , 2000 : 28A70
    • Michael McMullan, MD, Thelitz S, McMullan DM, Ovadia B, Bekker JM, Johengen MJ, Black SM, Sanchez LS, Fineman JR
      Inhaled nitric oxide alters endogenous phosphodiesterase activity in lambs
      Circulation , 2000 : 102(8)II-320
    • Michael McMullan, MD, McMullan DM, Bekker JM, Johengen MJ, Hendricks-Munoz K, Gerrets R, Black SM, Fineman JR
      Inhaled nitric oxide-induced rebound pulmonary hypertension: a role for endothelin-1
      American Physiology Society , 2000 : 70577H
    • McMullan DM, Bekker JM, Johengen MJ, Heidersbach RS, Black SK, Fineman JR
      Rebound pulmonary hypertension following inhaled nitric oxide therapy: a role for endothelin-1
      Journal of Thoracic and Cardiovascular Surgery , 2000 : 119(3)651
    • Riemer RK, McMullan DM, Malhotra SP, He YP, Reddy VM
      Upregulation of Tie-2 but not Tie-1 expression in a model of pulmonary arteriovenous malformations induced by alteration of pulmonary blood flow
      FASEB Journal , 2000 : 14(4)A686
    • Black SM, Heidersbach RS, McMullan DM, Bekker JM, Johengen MJ, Fineman JR
      Inhaled nitric oxide inhibits NOS activity in lambs: potential mechanism for rebound pulmonary hypertension.
      10564139 The American journal of physiology , 1999 Nov. : 277(5 Pt 2)H1849-56
    • Petrossian E, Parry AJ, Reddy VM, Akkersdijk GP, McMullan DM, Thompson L, Hendricks-Munoz KD, Hallak H, Hanley FL, Fineman JR
      Endothelin receptor blockade prevents the rise in pulmonary vascular resistance after cardiopulmonary bypass in lambs with increased pulmonary blood flow.
      9918974 The Journal of thoracic and cardiovascular surgery , 1999 Feb. : 117(2)314-23
    • McMullan DM, Riemer RK, Gottliebson WM, Kung GC, Yelich S, Reddy VM, Hanley FL
      Pulmonary arteriovenous shunting in fetal and neonatal lambs
      Pediatric Research , 1999 : 45(4 Part 2)27a, I1
    • Black SM, Heidersbach RS, McMullan DM, Bekker JM, Johengen MJ, Fineman JR
      A potential mechanism for rebound pulmonary hypertension
      Critical Care Medicine , 1999 : 27A39
    • Parry AJ, McMullan DM, Bekker JM, Johengen MJ, Heidersbach RS, Kon AA, Black SK, Fineman JR
      Endogenous nitric oxide production in a model of congenital heart disease with increased pulmonary blood flow: an 8 week follow-up
      Circulation , 1999 : 100(18)I-735
    • McMullan DM, He Y, Hanley FL, Reddy VM, Riemer RK
      Abnormal pulmonary vascular response to cavopulmonary anastomosis: increased angiogenic signaling
      Circulation , 1999 : 100(18)I170
    • McMullan DM, Bekker JM, Parry AJ, Johengen MJ, Heidersbach RS, Kon AA, Black SK, Fineman JR
      Endogenous nitric oxide production after cardiopulmonary bypass (CPB) in lambs with normal and increased pulmonary blood flow
      Circulation , 1999 : 100(18)I70
    • Riemer RK, McMullan DM, He Y, Hanley FL, Reddy VM
      Increased ecNOS expression after cavopulmonary anastomosis
      Federation of American Societies for Experimental Biology Journal , 1999 : 13(4 Part 1)A103
    • Gutierrez JA, Parry AJ, McMullan DM, Fineman JR
      Increased pulmonary blood flow decreases protein A in a lamb model of congenital heart disease
      352A Pediatric Research , 1999 : Pediatric Research(45)4
    • McMullan DM, Riemer RK, Gottliebson WM, Kung GC, Petrossian E, Hanley FL
      Pulmonary arteriovenous connections in fetal lambs
      Pediatric Research , 1999 : 45(4)27A
    • Riemer RK, McMullan DM, He Y, Hanley FL, Reddy VM
      Altered pulmonary gene expression following cavopulmonary anastomosis in young lambs
      Circulation , 1998 : 98(17)1268-9
    • Panis Y, McMullan DM, Emond JC
      Progressive necrosis after hepatectomy and the pathophysiology of liver failure after massive resection.
      9037225 Surgery , 1997 Feb. : 121(2)142-9
    • Nishimura N, Radovancevic B, Odegaard P, Meyers TJ, Springer WE, Beyer EAK, McMullan DM, Frazier OH
      Patients with renal dysfunction before left ventricular assist system (LVAS) implantation are poor transplant candidates and permanent LVAS may be indicated
      Journal of Heart and Lung Transplantation , 1997 : 16(1)94
    • Lyson T, McMullan DM, Ermel LD, Morgan BJ, Victor RG
      Mechanism of cyclosporine-induced sympathetic activation and acute hypertension in rats.
      8175178 Hypertension , 1994 May : 23(5)667-75
    • McMullan DM, Bumgardner GL, Hayes-Lattin B, Osorio RW, Ascher NL
      Preoperative serum arginase level as a predictor of rejection in human orthotopic liver recipients
      Hepatology , 1993 : 18(4 Part 2)338a
    • McMullan DM, Bumgardner GL, Hayes-Lattin B, Osorio RW, Ascher NL
      Arginase as an indicator of acute vs. ongoing hepatocellular damage
      Hepatology , 1993 : 18(4 Part 2)338a
    • Baumgardner GL, McMullan DM, Lin Z, Konstantinides FN, Cerra FB, Fasola C, Ascher NL
      The role of arginase in liver immunity
      Hepatology , 1993 : 18(4 Part 2)211a
    • Panis Y, Hayes-Lattin B, McMullan DM, Ascher NL, Emond JC
      Arginase serum profile after extensive hepatectomy in rats
      Hepatology , 1993 : 18(4 Part 2)192A
    • Dohanich GP, McMullan DM, Cada DA, Mangum KA
      Muscarinic receptor subtypes and sexual behavior in female rats.
      1708147 Pharmacology, biochemistry, and behavior , 1991 Jan. : 38(1)115-24
    • Lyson T, McMullan DM, Ermel LD, Morgan BJ, Victor RG
      Neural mechanisms of cyclosporine induced hypertension
      Clinical Research , 1990 : 38(4)947A
    • Dohanich GP, McMullan DM, Brazier MM
      Cholinergic regulation of sexual behavior in female hamsters.
      2326327 Physiology and behavior , 1990 Jan. : 47(1)127-31
    • Dohanich GP, Holland R, McMullan DM and Piazza A, Cada DA
      Inhibition of lordosis in rats and hamsters by muscarinic antagonists
      Society for Neuroscience Abstracts , 1988 : 14(1)275

  • Presentations Title Event Location Date
    ECLS Hands-on Training 7th World Congress on Pediatric Intensive and Critical Care Instanbul, Turkey May 4, 2014
    Developing an ECMO Simulation System 7th World Congress on Pediatric Intensive and Critical Care Instanbul, Turkey May 3, 2014
    Cardiac ECMO: Indications and Outcomes 7th World Congress on Pediatric Intensive and Critical Care Instanbul, Turkey May 3, 2014
    Cannula Selection and Cannulation Strategies for ECLS 7th World Congress on Pediatric Intensive and Critical Care Instanbul, Turkey May 3, 2014
    Congenital Cardiac Surgery Training and Experience at Seattle Children's Hospital Hospital Grand Rounds, National Pediatric Hospital Skopje, Macedonia March 6, 2014
    Hands-On ECMO Society of Critical Care Medicine's 43rd Crititcal Care Congress San Francisco, CA Jan. 9, 2014
    Cannulation: How to Do It and How Not to Do It - A Pictorial Guide Society of Critical Care Medicine's 43rd Critical Care Congress San Francisco, CA Jan. 9, 2014
    ECMO Case Studies - How I Do It 24th Annual Extracorporeal Life Support Organization Conference Philadelphia, PA Sept. 21, 2013
    New Generation Cardiac Assist Devices to Bridge to Cardiac Transplantation 6th Annual Lemire Northwest Symposium on Contemporary Pediatric Critical Care Medicine Seattle, WA July 26, 2013
    Economics of Mechanical Cardiac Support St. Christopher's Hospital for Children Philadelphia, PA May 20, 2013
    Optimal Surgical Approaches to Neonatal Aortic Stenosis and the Hypoplastic Arch American College of Cardiology Scientific Session San Francisco, CA March 10, 2013
    Management of Cardiac and SVC Perforation: To Boldly Go Where No Man has Gone Before 29th Annual CNMC Symposium on ECMO and Advance Therapies for Respiratory Failure Keystone, CO Feb. 27, 2013
    Mass Disaster Medicine: ECLS Support? Fantasy of Fiction 29th Annual CNMC Symposium on ECMO and Advance Therapies for Respiratory Failure Keystone, CO Feb. 27, 2013
    Utilization and Economics of Mechanical Support 9th International Conference of the Pediatric Cardiac Intensive Care Society Miami, FL Dec. 12, 2012
    ECLS Costs and Outcomes Vary by Program Size 23rd Annual Extracorporeal Life Support Organization Conference Seattle, WA Sept. 14, 2012
    Blalock-Taussig Shunt is the Best Choice for a 2.5 kg Patient with Tetralogy of Fallot Western Society of Pediatric Cardiology Annual Meeting Stevenson, WA June 9, 2012
    Supporting the Single Ventricle 1st Annual European Extracorporeal Life Support Organization Conference Rome, Italyl May 12, 2012
    Minimizing Perioperative Bleeding on ECMO 1st Annual European Extracorporeal Life Support Organization Conference Rome, Italy May 12, 2012
    ECMO in Preterm Neonates 22nd Annual Extracorporeal Life Support Organization Conference Phoenix, AZ Sept. 18, 2011
    ECMO for Cardiovascular Disease Diagnosis, Management and Prevention of Cardiovascular Disease Symposium Seattle, WA April 30, 2011
    Nightmare Cases in the Office: Cardiac Arrest and ECPR Western Society of Pediatric Cardiology Annual Meeting Rancho Palos Verdes, CA April 9, 2011
    Making the Jump to Centripetal and Quadrox 27th Annual CNMC Symposium on ECMO and Advanced Therapies for Respiratory Failure Keystone, CO Feb. 22, 2011
    Extracorporeal Support and VAD Therapy for Children Western Society of Pediatric Cardiology Annual Meeting Scottsdale, AZ April 18, 2010
    Trends and Advances in ECMO Department of Surgery Grand Rounds, University of Washington Seattle, WA April 7, 2010
    The Avalon Dual Lumen Venovenous Cannula: A Single Institution Experience 26th Annual CNMC Symposium on ECMO and Advance Therapies for Respiratory Failure Keystone, CO Feb. 24, 2010
    Managing Invasive Procedures in ECLS 19th Annual Specialist Education in Extracorporeal Membrane Oxygenation Conference Seattle, WA May 2, 2009
    Million Dollar Baby Pediatric Anesthesiology Annual Meeting Jacksonville, FL March 19, 2009
    Complex ECMO Scenarios The Childrens Hospital ECMO Course Denver, CO March 17, 2009
    Cardiac ECMO The Childrens Hospital ECMO Course Denver, CO March 17, 2009
    Surgery for Complex Congenital Heart Disease CICU Core Class, Seattle Childrens Hospital Seattle, WA March 10, 2009
    "Jostra Quadrox and Rotaflow ECLS: The Australian Experience" 25th Annual CNMC Symposium on ECMO and Advance Therapies for Respiratory Failure Keystone, CO Feb. 26, 2009
    ECPR: A New Approach to Rescuing Patients with Acute Cardiopulmonary Failure Hospital Grand Rounds, Seattle Children's Hospital Seattle, WA July 24, 2008
    Mechanical Support of the Postoperative Patient Western Society of Pediatric Cardiology Annual Meeting San Francisco, CA May 9, 2008
    Extracorporeal Life Support 35th Annual Pacific Northwest Regional Respiratory Care Conference Seattle, WA April 24, 2008
    Antibiotic Prophylaxis for Bacterial Endocarditis in Dentistry Seattle Pediatric Dentistry Study Group Seattle, WA Jan. 22, 2008
    Extracorporeal Membrane Oxygenation Cardiovascular Surgery Grand Rounds, University of Washington Seattle, WA Oct. 17, 2007
    Aortic Valve Repair Surgery Grand Rounds, Mulago Hospital Kampala, Uganda March 15, 2007
    Mechanical Support for Cardiopulmonary Failure Cardiology Grand Rounds, Children's National Medical Center Washington, DC Jan. 22, 2007
    Pediatric Heart Surgery National Youth Leadership Forum in Medicine Washington, DC June 29, 2006
    Thoracic Surgery Training in the United Statees: An Evolving Educational System 14th Annual Meeting of the Asian Society for Cardiovascular Surgery Osaka, Japan June 2, 2006
    Beyond Borders: Reflections on International Medical Service in Vietnam 114th Association of American Medical Colleges Annual Meeting Washington, DC Nov. 7, 2003
    Dental Antibiotic Prophylaxis and Cardiovascular Disease Dental School Grand Rounds, University of Washington Seattle, WA May 16, 2003
    Surgical Education and Practice in Vietnam General Surgery Grand Rounds, University of Texas Houston, TX June 4, 2002
    Blunt Thoracic Trauma Cardiothoracic and Vascular Surgery Grand Rounds, University of Texas Houston, TX May 24, 2002
    Splanchnic Artery Aneurysms Cardiovascular Surgery Grand Rounds, Texas Heart Institute Houston, TX April 18, 2001
  • Grant Title Grantor Amount Award Date
    Seattle Children's Academic Enrichment Fund Award Principal Investigator $50,000 (2 years) 2013 - 2015
    Extracorporeal Life Support Organization Research Award Principal Investigator $7,000 (1 year) 2011 - 2012
    Seattle Children's Academic Enrichment Fund Award Principal Investigator $24,745 (2 years) 2009 - 2011
    Children's National Medical Center Board of Visitors Award Principal Investigator $15,000 (1 year) 2006 - 2007
    NIH Individual National Research Service Award #HL10108-01 Principal Investigator $50,000 (1 year) 1998 - 1999

Overview

Board Certification(s)

Surgery - General
Congenital Cardiac Surgery
Thoracic Surgery

Medical/Professional School

UT Southwestern Medical School, Dallas

Residency

Surgery - General, University of Texas Medical School at Houston, Houston
Cardiothoracic Surgery, University of Washington School of Medicine, Seattle

Fellowship

University of California San Francisco, San Francisco
Pediatric Cardiothoracic Surgery, University of California San Francisco School of Medicine, San Francisco
Pediatric Cardiothoracic Surgery, Royal Children's Hospital, Parkville
Cardiac Transplant, Texas Heart Institute, Houston

Clinical Interests

Pediatric Cardiac Surgery, Mechanical Cardiac Support, Surgical Management of Congenital Heart Disease

Research Description

The focus of our research is developing improved mechanical extracorporeal life support systems (ECLS). Combined with optimized clinical management protocols, improved ECLS circuit designs provide increased clinical flexibility and patient safety. Current projects include system enhancements that enable decreased anticoagulation, reduced circuit size, and elimination of unnecessary components. Additionally, we are focusing on alternative methods of care provider education to increase quality assurance.

Research Focus Area

Quality Improvement, Congenital Cardiac Surgery Outcomes