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Cate Pihoker, MD

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Cate Pihoker, MD

Endocrinology, Diabetes Research, Disorders of Sex Development

On staff since July 1997

Children's Title: Program Director, Endocrinology Education; Clinic Chief, Diabetes/Endocrine (interim); Division Chief, Endocrinology

Academic Title: Professor

Research Center: Center for Clinical and Translational Research

Recommendations

KittRenton, WA04.23.13
Dr. Pihoker has been providing expert care to our daughter since she began throwing seizures at only 3 months of age! Where other doctors had struggled, Dr. P. made a quick and correct diagnosis of a very rare but treatable condition, hypoparathyroidism. My kid is now a healthy teenager and living a normal life, thanks in no small part to Dr. Pihoker and the CHMC team. The gratitude I feel for not only the knowledge and experience, but the unfailing kindness and patience with parental questions and concerns, can barely be put into words. Dr. Pihoker is the best!
JeanneMilton, WA03.31.11
I can recommend Dr. Pihoker without reservation for any patient who needs to see an endocrine or diabetes specialist. She works with families and children in a supportive way which allows the child to gradually take on appropriate self-care, and encourages families to learn about their child's condition to help make decisions about long term treatment plans (or tweeks of plans as new needs come up). Although Dr. Pihoker doesn't waste appointment time on chit-chat, we feel she shows genuine concern and interest in our son as her patient, and has become a partner in his care. Our son has been her patient for about 12 of his 14 years of diabetes care at Children's and we are truly thankful for her guidance over the years.
Recommend Dr. Cate Pihoker

Overview

Board Certification(s)
Pediatric Endocrinology
Medical/Professional School
Jefferson Medical College of Thomas Jefferson University, Philadelphia
Residency
Pediatrics, Hershey Medical Center, Hershey
Fellowship
Pediatric Endocrinology, Duke University Medical Center, Durham
Clinical Interests

Diabetes

Research Focus Area

Diabetes

Awards and Honors

Award NameAward DescriptionAwarded ByAward Date
SEATTLE MAGAZINE TOP DOCTOR - 2014Seattle Magazine 2014
SEATTLE'S TOP DOCTOR - 2014Seattle Metropolitan Magazine 2014
Seattle Magazine Top Doctor - 2013Seattle Magazine 2013
Diabetes Care Community Ambassador ProjectThe Washington State Office of the Attorney General 2013

Publications

Re: "Prevalence of Diagnosed and Undiagnosed Type 2 Diabetes Mellitus Among US Adolescents: Results From the Continuous NHANES, 1999-2010".
American journal of epidemiology , 2014 Feb 1: 179(3)396-7
Correlates of treatment patterns among youth with type 2 diabetes.
Diabetes care , 2014 Jan: 37(1)64-72
Peripheral neuropathy in adolescents and young adults with type 1 and type 2 diabetes from the SEARCH for Diabetes in Youth follow-up cohort: a pilot study.
Diabetes care , 2013 Dec: 36(12)3903-8
Vitamin D in youth with Type 1 diabetes: prevalence of insufficiency and association with insulin resistance in the SEARCH Nutrition Ancillary Study.
Diabetic medicine : a journal of the British Diabetic Association , 2013 Nov: 30(11)1324-32
Digenic heterozygous HNF1A and HNF4A mutations in two siblings with childhood-onset diabetes.
Pediatric diabetes , 2013 Nov: 14(7)535-8
Change in fractional anisotropy during treatment of diabetic ketoacidosis in children.
Pediatric research , 2013 Oct 8
Prevalence, characteristics and clinical diagnosis of maturity onset diabetes of the young due to mutations in HNF1A, HNF4A, and glucokinase: results from the SEARCH for Diabetes in Youth.
The Journal of clinical endocrinology and metabolism , 2013 Oct: 98(10)4055-62
Prevalence, characteristics and clinical diagnosis of maturity onset diabetes of the young due to mutations in HNF1A, HNF4A, and glucokinase: results from the SEARCH for Diabetes in Youth.
The Journal of clinical endocrinology and metabolism , 2013 Oct: 98(10)4055-62
Prevalence of Diabetes Mellitus in U.S. Youth in 2009: The SEARCH for Diabetes in Youth Study.
Diabetes care , 2013 Sep 16
Nutritional factors and preservation of C-peptide in youth with recently diagnosed type 1 diabetes: SEARCH Nutrition Ancillary Study.
Diabetes care , 2013 Jul: 36(7)1842-50
Fructose intake and cardiovascular risk factors in youth with type 1 diabetes: SEARCH for diabetes in youth study.
Diabetes research and clinical practice , 2013 May: 100(2)265-71
Permanent neonatal diabetes mellitus: prevalence and genetic diagnosis in the SEARCH for Diabetes in Youth Study.
Pediatric diabetes , 2013 May: 14(3)174-80
Transition from pediatric to adult care for youth diagnosed with type 1 diabetes in adolescence.
Pediatrics , 2013 Apr: 131(4)e1062-70
HLA-associated phenotypes in youth with autoimmune diabetes.
Pediatric diabetes , 2013 Mar: 14(2)121-8
Insulin regimens and clinical outcomes in a type 1 diabetes cohort: the SEARCH for Diabetes in Youth study.
Diabetes care , 2013 Jan: 36(1)27-33
Glucose control predicts 2-year change in lipid profile in youth with type 1 diabetes.
The Journal of pediatrics , 2013 Jan: 162(1)101-7.e1
Clinical evolution of beta cell function in youth with diabetes: the SEARCH for Diabetes in Youth study.
Diabetologia , 2012 Dec: 55(12)3359-68
The T1D Exchange clinic registry.
The Journal of clinical endocrinology and metabolism , 2012 Dec: 97(12)4383-9
Migration status in relation to clinical characteristics and barriers to care among youth with diabetes in the US.
Journal of immigrant and minority health / Center for Minority Public Health , 2012 Dec: 14(6)949-58
Diabetic retinopathy in the SEARCH for Diabetes in Youth Cohort: a pilot study.
Diabetic medicine : a journal of the British Diabetic Association , 2012 Sep: 29(9)1148-52
Correlation of TSH with the risk of paediatric thyroid carcinoma.
Clinical endocrinology , 2012 Aug: 77(2)316-22
Demographic and clinical correlates of diabetes-related quality of life among youth with type 1 diabetes.
The Journal of pediatrics , 2012 Aug: 161(2)201-7.e2
Comparison of mercury and aneroid blood pressure measurements in youth.
Pediatrics , 2012 May: 129(5)e1205-10
Type 2 diabetes in childhood: clinical characteristics and role of -cell autoimmunity.
Current diabetes reports , 2012 Feb: 12(1)75-81
Reduced prevalence of diabetic ketoacidosis at diagnosis of type 1 diabetes in young children participating in longitudinal follow-up.
Diabetes care , 2011 Nov: 34(11)2347-52
Change in mean transit time, apparent diffusion coefficient, and cerebral blood volume during pediatric diabetic ketoacidosis treatment.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2011 Nov: 12(6)e344-9
Prevalence of asthma and its association with glycemic control among youth with diabetes.
Pediatrics , 2011 Oct: 128(4)e839-47
Adherence to guidelines for youths with diabetes mellitus.
Pediatrics , 2011 Sep: 128(3)531-8
Etiological approach to characterization of diabetes type: the SEARCH for Diabetes in Youth Study.
Diabetes care , 2011 Jul: 34(7)1628-33
Hypertension despite dehydration during severe pediatric diabetic ketoacidosis.
Pediatric diabetes , 2011 Jun: 12(4 Pt 1)295-301
Association testing of TCF7L2 polymorphisms with type 2 diabetes in multi-ethnic youth.
Diabetologia , 2011 Mar: 54(3)535-9
Impact of heterozygosity for acid-labile subunit (IGFALS) gene mutations on stature: results from the international acid-labile subunit consortium.
The Journal of clinical endocrinology and metabolism , 2010 Sep: 95(9)4184-91
Prevalence and correlates of elevated blood pressure in youth with diabetes mellitus: the SEARCH for diabetes in youth study.
The Journal of pediatrics , 2010 Aug: 157(2)245-251.e1
Change in blood-brain barrier permeability during pediatric diabetic ketoacidosis treatment.
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2010 May: 11(3)332-8
Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects.
Diabetes , 2010 Feb: 59(2)407-15
Complementary and alternative medicine use and quality of life in pediatric diabetes.
Journal of alternative and complementary medicine (New York, N.Y.) , 2010 Feb: 16(2)165-73
Prevalence of overweight and obesity in youth with diabetes in USA: the SEARCH for Diabetes in Youth study.
Pediatric diabetes , 2010 Feb: 11(1)4-11
Designing and implementing sample and data collection for an international genetics study: the Type 1 Diabetes Genetics Consortium (T1DGC).
Clinical trials (London, England) , 2010: 7(1 Suppl)S5-S32
Glycemic control in youth with diabetes: the SEARCH for diabetes in Youth Study.
The Journal of pediatrics , 2009 Nov: 155(5)668-72.e1-3
Preservation of beta-cell function in autoantibody-positive youth with diabetes.
Diabetes care , 2009 Oct: 32(10)1839-44
Assessment and monitoring of glycemic control in children and adolescents with diabetes.
Pediatric diabetes , 2009 Sep: 10 Suppl 1271-81
The delivery of ambulatory diabetes care to children and adolescents with diabetes.
Pediatric diabetes , 2009 Sep: 10 Suppl 1258-70
Predictors of insulin regimens and impact on outcomes in youth with type 1 diabetes: the SEARCH for Diabetes in Youth study.
The Journal of pediatrics , 2009 Aug: 155(2)183-9.e1
The association between adiponectin/leptin ratio and diabetes type: the SEARCH for Diabetes in Youth Study.
The Journal of pediatrics , 2009 Jul: 155(1)133-5, 135.e1
Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects.
European journal of immunology , 2009 Feb: 39(2)612-20
Three novel IGFALS gene mutations resulting in total ALS and severe circulating IGF-I/IGFBP-3 deficiency in children of different ethnic origins.
Hormone research , 2009: 71(2)100-10
The delivery of ambulatory diabetes care: structures, processes, and outcomes of ambulatory diabetes care.
Pediatric diabetes , 2008 Dec: 9(6)609-20
The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) , 2008 Nov 15: 181(10)7350-5
CD4+ T cells from type 1 diabetic and healthy subjects exhibit different thresholds of activation to a naturally processed proinsulin epitope.
Journal of autoimmunity , 2008 Aug: 31(1)30-41
Health-related quality of life of children and adolescents with type 1 or type 2 diabetes mellitus: SEARCH for Diabetes in Youth Study.
Archives of pediatrics & adolescent medicine , 2008 Jul: 162(7)649-57
Presence of diabetic ketoacidosis at diagnosis of diabetes mellitus in youth: the Search for Diabetes in Youth Study.
Pediatrics , 2008 May: 121(5)e1258-66
Use of oral glucose minimal model-derived index of insulin sensitivity in subjects with early type 1 diabetes mellitus.
Metabolism: clinical and experimental , 2008 Apr: 57(4)445-7
Prevalence and determinants of elevated apolipoprotein B and dense low-density lipoprotein in youths with type 1 and type 2 diabetes.
The Journal of clinical endocrinology and metabolism , 2008 Mar: 93(3)735-42
Assessment and monitoring of glycemic control in children and adolescents with diabetes.
Pediatric diabetes , 2007 Dec: 8(6)408-18
Family history of diabetes, autoimmunity, and risk factors for cardiovascular disease among children with diabetes in the SEARCH for Diabetes in Youth Study.
Pediatric diabetes , 2007 Dec: 8(6)354-61
Obesity and hypertension among children after treatment for acute lymphoblastic leukemia.
Cancer , 2007 Nov 15: 110(10)2313-20
A Gender Assessment Team: experience with 250 patients over a period of 25 years.
Genetics in medicine : official journal of the American College of Medical Genetics , 2007 Jun: 9(6)348-57
Early childhood gender differences in anterior and posterior cerebral blood flow velocity and autoregulation.
Pediatrics , 2007 Mar: 119(3)e610-5
Serum lipids and glucose control: the SEARCH for Diabetes in Youth study.
Archives of pediatrics & adolescent medicine , 2007 Feb: 161(2)159-65
Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives.
Diabetes , 2006 Nov: 55(11)3061-7
Lipid abnormalities are prevalent in youth with type 1 and type 2 diabetes: the SEARCH for Diabetes in Youth Study.
The Journal of pediatrics , 2006 Sep: 149(3)314-9
Dietary intake among youth with diabetes: the SEARCH for Diabetes in Youth Study.
Journal of the American Dietetic Association , 2006 May: 106(5)689-97
What type of diabetes do young people have?
Current diabetes reports , 2006 Apr: 6(2)108-12
Evaluation of leptin levels in subjects at risk for type 1 diabetes.
Journal of autoimmunity , 2006 Mar: 26(2)133-7
Islet-specific glucose-6-phosphatase catalytic subunit-related protein-reactive CD4+ T cells in human subjects.
Journal of immunology (Baltimore, Md. : 1950) , 2006 Mar 1: 176(5)2781-9
Testing the accelerator hypothesis: body size, beta-cell function, and age at onset of type 1 (autoimmune) diabetes.
Diabetes care , 2006 Feb: 29(2)290-4
Autoantibodies in diabetes.
Diabetes , 2005 Dec: 54 Suppl 2S52-61
Autoimmunity and clinical course in children with type 1, type 2, and type 1.5 diabetes.
Journal of autoimmunity , 2005 Nov: 25(3)244-50
Type 2 diabetes in youth.
Current problems in pediatric and adolescent health care , 2004 Aug: 34(7)254-72
The case for intravenous arginine stimulation in lieu of mixed-meal tolerance tests as outcome measure for intervention studies in recent-onset type 1 diabetes.
Diabetes care , 2004 May: 27(5)1202-4
Autoimmunity to islet proteins in children diagnosed with new-onset diabetes.
The Journal of clinical endocrinology and metabolism , 2004 May: 89(5)2222-7
Continuity and quality of care for children with diabetes who are covered by medicaid.
Ambulatory pediatrics : the official journal of the Ambulatory Pediatric Association , 2001 Mar-Apr: 1(2)99-103
Does short-term antiepileptic drug treatment in children result in cognitive or behavioral changes?
Epilepsia , 1998 Oct: 39(10)1064-9
Pharmacokinetics and pharmacodynamics of growth hormone-releasing peptide-2: a phase I study in children.
The Journal of clinical endocrinology and metabolism , 1998 Apr: 83(4)1168-72
Non-insulin dependent diabetes mellitus in African-American youths of Arkansas.
Clinical pediatrics , 1998 Feb: 37(2)97-102
Treatment effects of intranasal growth hormone releasing peptide-2 in children with short stature.
The Journal of endocrinology , 1997 Oct: 155(1)79-86
Characteristics of youth-onset noninsulin-dependent diabetes mellitus and insulin-dependent diabetes mellitus at diagnosis.
Pediatrics , 1997 Jul: 100(1)84-91
Effective use of magnetic resonance imaging in the assessment of children with possible growth hormone deficiency.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists , 1996 Jan-Feb: 2(1)8-12
Diagnostic studies with intravenous and intranasal growth hormone-releasing peptide-2 in children of short stature.
The Journal of clinical endocrinology and metabolism , 1995 Oct: 80(10)2987-92
Rat placental lactogen-I binds to the choroid plexus and hypothalamus of the pregnant rat.
The Journal of endocrinology , 1993 Nov: 139(2)235-42
Pregnancy lactogens in the rat conceptus and fetus: circulating levels, distribution of binding, and expression of receptor messenger ribonucleic acid.
Endocrinology , 1993 Oct: 133(4)1830-42
Maternal separation in neonatal rats elicits activation of the hypothalamic-pituitary-adrenocortical axis: a putative role for corticotropin-releasing factor.
Psychoneuroendocrinology , 1993: 18(7)485-93
Postnatal development of regional binding of corticotropin-releasing factor and adenylate cyclase activity in the rat brain.
Progress in neuro-psychopharmacology & biological psychiatry , 1992 Jul: 16(4)581-6
Lipocortin-I inhibits the synthesis and release of prolactin from human decidual cells: evidence for autocrine/paracrine regulation by lipocortin-I.
Endocrinology , 1991 Feb: 128(2)1123-8

Research Funding

Grant TitleGrantorAmountAward Date
Monogenic Diabetes – an Ancillary Study of SEARCH for Diabetes in YouthJuvenile Diabetes Research Foundation, Wake Forest UniversityMarch 1, 2008
Nutrition and Metabolic Status in Youth with Type 1 DM- SEARCH Ancillary StudyNIH, NIDDK, University of South CarolinaFeb. 1, 2008
JDRF-BRI Center for Translational ResearchJuvenile Diabetes Research FoundationJan. 1, 2008
SEARCH for Diabetes in Youth 2- Washington SiteNIH CDCSept. 30, 2005
Type 1 Diabetes Genetics ConsortiumNIDDK, Benaroya Research Institute Virginia MasonSept. 1, 2004
TrialNet Clinical Agreement, site 307NIH/NIDDKOct. 1, 2002

Primary Office

Seattle Children's
OC.7.820 - Endocrinology
4800 Sand Point Way NE
Seattle, WA 98105
206-987-5037

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