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Brandon K. Hadland, MD, PhD

Brandon K. Hadland, MD, PhD


On staff since July 2012

"I am amazed and humbled every day by the strength and resilience of our patients and their families; they are an inspiration for us to continue the pursuit of researching novel therapies and improving clinical care. My long-term research goal is to generate new sources of blood stem cells that could one day be used to correct inherited, blood-based diseases."


Board Certification(s)
Pediatric Hematology-Oncology
Medical/Professional School
Washington University School of Medicine, St Louis
Pediatrics, University of Washington/Seattle Children's Hospital, Seattle
Hematology, University of Washington, Seattle
Hematology, University of Washington, Seattle
Clinical Interests

Stem cell transplant

Research Description

Signal pathways regulating hematopoietic stem cell development

Awards and Honors

Award NameAward DescriptionAwarded ByAward Date
Alpha Omega Alpha Honor Medical Society 2006
Chemistry Departmental HonorsPhi Lambda Upsilon Honorary Chemical Society 1998


Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors.
Cell stem cell , Oct. 2013: 13(4)459-70
Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development.
Development (Cambridge, England) , Sept. 2013: 140(18)3799-808
Visualizing human ESC-derived hematopoiesis.
Blood , Jan. 2013: 121(5)717-8
Erythroid-stimulating agents in cancer therapy: potential dangers and biologic mechanisms.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology , Sept. 2009: 27(25)4217-26
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE.
Development (Cambridge, England) , Feb. 2007: 134(3)535-44
A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development.
Blood , Nov. 2004: 104(10)3097-105
Notch pathway is dispensable for adipocyte specification.
Genesis (New York, N.Y. : 2000) , Sept. 2004: 40(1)40-4
Gamma -secretase inhibitors repress thymocyte development.
Proceedings of the National Academy of Sciences of the United States of America , June 2001: 98(13)7487-91
A molecular phylogenetic analysis of reproductive trait evolution in the soft coral genus Alcyonium
Evolution Int J Org Evolution , 2001: 5554-67

Research Funding

Grant TitleGrantorAmountAward Date
K12 CA076930 Career Development in Pediatric and Medical OncologyNIH $, $
T32 CA009351 NCI: Pediatric Oncology Training ProgramNCI

Primary Office

Seattle Children's
MB.8.501 - Hematology-Oncology
4800 Sand Point Way NE
Seattle, WA 98105

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