Grundner Lab

Selected Publications

Listed below is a selection of recent publications from the Grundner Lab.

Mycobacterium tuberculosis Rv3631 is a triple sensor-domain protein. Abendroth J, Frando A, Phan IQ, Staker BL, Myler PJ, Edwards TE, Grundner C. Protein Sci. 2018 Feb; 27(2):568-572.

Systematic survey of serine hydrolase activity in Mycobacterium tuberculosis defines changes associated with persistence. Ortega C, Anderson LN, Frando A, Sadler NC, Brown RW, Smith RD, Wright AT, Grundner C. Cell Chem Biol. 2016 Feb 18;23 (2):290-298.

Mycobacterium tuberculosis supports protein tyrosine phosphorylation. Kusebauch U, Ortega C, Ollodart A, Rogers RS, Sherman DR, Moritz RL, Grundner C. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9265-70.

Mycobacterium tuberculosis Ser/Thr protein kinase B mediates an oxygen-dependent replication switch. Ortega C, Liao R, Anderson LN, Rustad T, Ollodart AR, Wright AT, Sherman DR, Grundner C. PLoS Biology 2014 12(1):e1001746.

Mycobacterium tuberculosis Rv2179c protein establishes a new exoribonuclease family with broad phylogenetic distribution. Abendroth J, Ollodart A, Andrews ES, Myler PJ, Staker BL, Edwards TE, Arcus VL, Grundner C. J Biol Chem. 2014 Jan 24;289(4):2139-47.

Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase. Stavroula K. Hatzios, Christina E. Baer, Tige R. Rustad, M. Sloan Siegrist, Jennifer M. Pang, Corrie Ortega, Tom Alber, Christoph Grundner, David R. Sherman, and Carolyn R. Bertozzia. Proc Natl Acad Sci U S A. 2013 Dec 24; 110(52).

Identification of widespread adenosine nucleotide binding in Mycobacterium tuberculosis. Ansong C, Ortega C, Payne SH, … Grundner C, Wright AT. Chem Biol. 2013 Jan 24;20(1):123-33

Novel and widespread adenosine nucleotide-binding in Mycobacterium tuberculosis. Charles Ansong, Corrie Ortega, Samuel H. Payne, … Christoph Grundner, and Aaron T. Wright. Chem Biol. 2013 Jan 24; 20(1): 123–133.