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Helen L. Dichek, MD

Helen L. Dichek, MD

Lipid Disorders, Endocrinology

On staff since February 2001

Academic Title: Associate Professor, Pediatrics - Division of Endocrinology


JessicaFederal Way, Wa12.27.13
What a breath of fresh air! Our appointment today went very well. Our daughter was responsive to the doctor, and we were more than pleased with how thorough she was in our complicated situation. I feel very confident that we are headed in the right direction and feel more reassured that answers are on the horizon. Like usual, Children's is the best!
JenniferBellingham, WA10.25.13
Dr. Dichek is the most fabulous doctor on our son's care team. She is so good with children, and I am fascinated by her level of knowledge each time we see her. She is an advocate for our son, and time and time again she goes above and beyond in working towards finding medical reasons that attribute to Dominic's quality of life. I have the most trust and faith in Dr. Dichek's care and skill than with any other doctor.
ToniHoquiam, WA02.28.12
My daughter absolutely loves Dr. Dichek. We have been going to her for several years and you could not ask for more. She is kind, considerate, caring and so very knowledgeable. She is wonderful with children. Like most children my daughter doesn't love going to the doctor, but when I let her know she is seeing Dr. Dichek her mood totally 360's because she is excited to get to go see her.
AmySeattle, WA11.10.11
I loved my experience with Dr Dichek. She is brilliant, attentive, and goes out of her way to provide the best care I've received from any specialist. She makes patients feel comfortable while performing high level assessments and diagnosis. She also has a great understanding of genetics.
VivianBellingham, WA05.06.11
Dr. Dichek is so wonderful! She is very kind, patient, understanding and compassionate. She definitely has knowledge of Diabetes and is thoughtful in presenting the information both to the patient and family. My son is a normal 15-year-old and she knew how to talk to him so that he felt a part of his treatment. I also love her accent! Thank you!
JesseSeattle, WA03.17.11
Dr. Dichek was wonderful with my 2 year old son. She was patient and kind and allowed him to have choices during our initial visit. While we don't know the outcome for our child, we feel confortable with her commitment to seeing his development over time!
Recommend Dr. Helen Dichek


Board Certification(s)
Pediatric Endocrinology
Medical/Professional School
Kath University Leuven, Leuven
Pediatrics, Cedars-Sinai Medical Center, Los Angeles
Pediatric Endocrinology, Los Angeles County Harbor - UCLA Medical Center, Torrance
Pediatric Endocrinology, Massachusetts General Hospital, Boston
Pediatric Endocrinology, NIH-NICHD, Bethesda
Clinical Interests

Lipid physiology and disorders


Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis.
Molecular therapy : the journal of the American Society of Gene Therapy , 2011 Oct: 19(10)1833-41
Mechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteins.
The Journal of biological chemistry , 2011 Jun 24: 286(25)22665-77
Mice lacking hepatic lipase are lean and protected against diet-induced obesity and hepatic steatosis.
Endocrinology , 2010 Mar: 993-1001
Level of macrophage uPA expression is an important determinant of atherosclerotic lesion growth in Apoe-/- mice.
Arteriosclerosis, thrombosis, and vascular biology , 2009 Nov: 1737-44
TGF-[beta]1 limits plaque growth, stabilizes plaque structure, and prevents aortic dilation in apolipoprotein E-null mice.
Arteriosclerosis, thrombosis, and vascular biology , 2009 Sep: 1251-7
Energy balance in congenital generalized lipodystrophy type I.
Metabolism: clinical and experimental , 2008 Aug: 1155-61
Hormonal regulation of testicular steroid and cholesterol homeostasis.
Molecular endocrinology (Baltimore, Md.) , 2008 Mar: 623-35
Reduced atherosclerosis in chow-fed mice expressing high levels of a catalytically inactive human hepatic lipase.
Atherosclerosis , 2007 Nov: 66-74
Attenuated corticosterone response to chronic ACTH stimulation in hepatic lipase-deficient mice: evidence for a role for hepatic lipase in adrenal physiology.
American journal of physiology. Endocrinology and metabolism , 2006 May: E908-15
Divergent effects of the catalytic and bridging functions of hepatic lipase on atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology , 2004 Sep: 1696-702
Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death.
Circulation , 2004 May 4: 2129-35
The bridging function of hepatic lipase clears plasma cholesterol in LDL receptor-deficient "apoB-48-only" and "apoB-100-only" mice.
Journal of lipid research , 2004 Mar: 551-60
Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms.
Genomics , 2004 Jan: 24-33

Research Funding

Grant TitleGrantorAmountAward Date
Research Collaboration on Hepatic LipaseTakeda Pharmaceutical Company $719,000.00April 1, 2009

Primary Office

University of Washington
UW Box 356320 - Endocrinology
1959 NE Pacific St
Seattle, WA 98195-6320

Additional Offices

Seattle Children's
OC.7.820 - Endocrinology
4800 Sand Point Way NE
Seattle, WA 98105

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