Profile

Eric J. Chow, MD, MPH

Eric J. Chow, MD, MPH

Hematology-Oncology

On staff since July 2007

Academic Title: Assistant Professor

Research Center: Center for Clinical and Translational Research

"My goal is not just to improve cure rates for childhood cancer, but to improve the quality of life for children and families dealing with and successfully overcoming cancer."

Eric Chow, MD, MPH, is an attending physician at Seattle Childrens Hospital, assistant professor of pediatrics at the University of Washington School of Medicine, and a member of the Clinical Research and Public Health Sciences Divisions at the Fred Hutchinson Cancer Research Center. His clinical and research interests focus on cancer survivorship, and he is the medical director of the childhood cancer survivor program at Seattle Childrens.

Together with other members of the Cancer and Blood Disorders Center, the goal of the cancer survivor program is to enhance patient and family awareness of potential cancer therapy-related late effects, and to maximize quality of life by early detection and treatment of these late effects. Dr. Chow's current research attempts to better understand risk factors that contribute to increased metabolic and cardiovascular complications following cancer therapy, with studies examining glucocorticoid pharmacogenetics in relation to obesity following leukemia therapy, treatment and genetic factors that contribute to cardiovascular toxicity following hematopoietic cell transplantation, and application of population-based databases to study cancer late effects. Related to these interests, Dr. Chow holds leadership positions within the Childrens Oncology Groups Outcomes and Survivorship Committee and the National Cancer Institute sponsored Childhood Cancer Survivor Study.

Making A Difference

Recommendations

  • Debbie Bellingham, WA 10.02.11

    Dr. Chow is terrific at communicating honestly & medically in a way that is easy to understand during a very difficult time. I found Dr. Chow passionate & earnest in caring for the children on the hem/onc floor. And as a mother of a child who underwent cancer treatment at Seattle Children's, I always felt a greater sense of comfort knowing we were in the care of Dr. Chow.

Overview

Board Certification(s)

Pediatrics
Pediatric Hematology-Oncology

Medical/Professional School

University of California, San Francisco, San Francisco
University of California , Berkeley

Residency

Pediatrics, University of Washington School of Medicine, Seattle

Fellowship

Pediatric Hematology-Oncology, Fred Hutchinson Cancer Research Center, Seattle

Research Description

I am a pediatric oncologist whose research focuses on cancer survivorship. My group is interested in better understanding the burden and risk factors for various endocrine/metabolic (e.g. obesity, insulin resistance) and cardiovascular outcomes following childhood cancer therapy. To this end, we utilize data from medical records as well as prospectively bring patients back to clinic for various physiologic measurements. Our survivorship research also includes work examining various gene polymorphisms of interest and data linkage strategies utilizing state administrative databases.

Research Focus Area

Chronic Conditions / Special Health Care Needs, Epidemiology, Cancer

Awards and Honors

Award Name Award Description Awarded By Award Date
Special Fellowship in Clinical Research Leukemia and Lymphoma Society July 1, 2008 - June 30, 2011
New Investigator Award American Society for Blood and Marrow Transplantation July 1, 2008 - June 30, 2010
Young Investigator Award American Society of Clinical Oncology / Lance Armstrong Foundation July 1, 2007 - June 30, 2008

Publications

  • Behren JV, Spector LG, Mueller BA, Carozza SE, Chow EJ, Fox EE, Horel S, Johnson KJ, McLaughlin C, Puumala SE, Ross JA, Reynolds P
    Birth order and risk of childhood cancer: A pooled analysis from five U.S. states.
    International journal of cancer. Journal international du cancer , 2010 Aug. 16
  • Chow EJ, Puumala SE, Mueller BA, Carozza SE, Fox EE, Horel S, Johnson KJ, McLaughlin CC, Reynolds P, Von Behren J, Spector LG
    Childhood cancer in relation to parental race and ethnicity: a 5-state pooled analysis.
    Cancer , 2010 June 15 : 3045-53
  • Chow EJ, Simmons JH, Roth CL, Baker KS, Hoffmeister PA, Sanders JE, Friedman DL
    Increased cardiometabolic traits in pediatric survivors of acute lymphoblastic leukemia treated with total body irradiation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation , 2010 May 31
  • Meacham LR, Chow EJ, Ness KK, Kamdar KY, Chen Y, Yasui Y, Oeffinger KC, Sklar CA, Robison LL, Mertens AC
    Cardiovascular risk factors in adult survivors of pediatric cancer--a report from the childhood cancer survivor study.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology , 2010 Jan. : 170-81
  • Mueller BA, Chow EJ, Kamineni A, Daling JR, Fraser A, Wiggins CL, Mineau GP, Hamre MR, Severson RK, Drews-Botsch C
    Pregnancy outcomes in female childhood and adolescent cancer survivors: a linked cancer-birth registry analysis.
    Archives of pediatrics & adolescent medicine , 2009 Oct. : 879-86
  • Chow EJ, Kamineni A, Daling JR, Fraser A, Wiggins CL, Mineau GP, Hamre MR, Severson RK, Drews-Botsch C, Mueller BA
    Reproductive outcomes in male childhood cancer survivors: a linked cancer-birth registry analysis.
    Archives of pediatrics & adolescent medicine , 2009 Oct. : 887-94
  • Chow EJ, Friedman DL, Stovall M, Yasui Y, Whitton JA, Robison LL, Sklar CA
    Risk of thyroid dysfunction and subsequent thyroid cancer among survivors of acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study.
    Pediatric blood & cancer , 2009 Sept. : 432-7
  • Johnson KJ, Carozza SE, Chow EJ, Fox EE, Horel S, McLaughlin CC, Mueller BA, Puumala SE, Reynolds P, Von Behren J, Spector LG
    Parental age and risk of childhood cancer: a pooled analysis.
    Epidemiology (Cambridge, Mass.) , 2009 July : 475-83
  • Spector LG, Puumala SE, Carozza SE, Chow EJ, Fox EE, Horel S, Johnson KJ, McLaughlin CC, Reynolds P, Behren JV, Mueller BA
    Cancer risk among children with very low birth weights.
    Pediatrics , 2009 July : 96-104
  • Armstrong GT, Whitton JA, Gajjar A, Kun LE, Chow EJ, Stovall M, Leisenring W, Robison LL, Sklar CA
    Abnormal timing of menarche in survivors of central nervous system tumors: A report from the Childhood Cancer Survivor Study.
    Cancer , 2009 June 1 : 2562-70
  • Robison LL, Armstrong GT, Boice JD, Chow EJ, Davies SM, Donaldson SS, Green DM, Hammond S, Meadows AT, Mertens AC, Mulvihill JJ, Nathan PC, Neglia JP, Packer RJ, Rajaraman P, Sklar CA, Stovall M, Strong LC, Yasui Y, Zeltzer LK
    The Childhood Cancer Survivor Study: a National Cancer Institute-supported resource for outcome and intervention research.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2009 May 10 : 2308-18
  • Diller L, Chow EJ, Gurney JG, Hudson MM, Kadin-Lottick NS, Kawashima TI, Leisenring WM, Meacham LR, Mertens AC, Mulrooney DA, Oeffinger KC, Packer RJ, Robison LL, Sklar CA
    Chronic disease in the Childhood Cancer Survivor Study cohort: a review of published findings.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2009 May 10 : 2339-55
  • Puumala SE, Carozza SE, Chow EJ, Fox EE, Horel S, Johnson KJ, McLaughlin C, Mueller BA, Reynolds P, Von Behren J, Spector LG
    Childhood cancer among twins and higher order multiples.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology , 2009 Jan. : 162-8
  • Armstrong GT, Chow EJ, Sklar CA
    Alterations in pubertal timing following therapy for childhood malignancies.
    Endocrine development , 2009 : 25-39
  • Chow EJ, Friedman DL, Yasui Y, Whitton JA, Stovall M, Robison LL, Sklar CA
    Timing of menarche among survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study.
    Pediatric blood & cancer , 2008 Apr, : 854-8
  • Chow EJ, Pihoker C, Hunt K, Wilkinson K, Friedman DL
    Obesity and hypertension among children after treatment for acute lymphoblastic leukemia.
    Cancer , 2007 Nov. 15 : 2313-20
  • Chow EJ, Friedman DL, Yasui Y, Whitton JA, Stovall M, Robison LL, Sklar CA
    Decreased adult height in survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor Study.
    The Journal of pediatrics , 2007 Apr, : 370-5, 375.e1
  • Chow EJ, Friedman DL, Mueller BA
    Maternal and perinatal characteristics in relation to neuroblastoma.
    Cancer , 2007 Mar. 1 : 983-92
  • Chow EJ, Holly EA
    Blood transfusions as a risk factor for non-Hodgkin's lymphoma in the San Francisco Bay Area: a population-based study.
    American journal of epidemiology , 2002 Apr, 15 : 725-31
  • Chow EJ, Holly EA
    Blood transfusions and non-Hodgkin's lymphoma.
    Epidemiologic reviews , 2002 : 269-79

Presentations

Presentations Title Event Location Date
Cardiometabolic complications after cancer therapy Grand Rounds St Jude Children's Research Hospital March 2011
5. Adult survivors of childhood cancer – part of Cancer survivorship for the primary care clinician Fred Hutchinson Cancer Research Center / University of Washington CME symposium Seattle, WA Jan. 1, 2009

Research Funding

Grant Title Grantor Amount Award Date
Determinants of late cardiovascular morbidity among survivors of hematopoietic cell transplantation National Cancer Institute Aug. 1, 2011 - July 30, 2016
Glucocorticoid pharmacogenetics and obesity after childhood ALL therapy Center for Clinical & Translational Research Pediatric Pilot Award Dec. 1, 2008
Unrestricted funds for research support Hyundai Hope on Wheels Cancer Research Scholarship Oct. 1, 2008
Glucocorticoid pharmacogenetics and obesity after childhood ALL therapy Leukemia & Lymphoma Society July 1, 2008
Late cardiovascular morbidity and mortality after allogeneic hematopoietic cell transplantation - a population-based analysis ASBMT $unknown July 1, 2008
A pilot study to determine the prevalence, risk factors, and biomarkers associated with the metabolic syndrome in childhood acute lymphoblastic leukemia survivors, comparing conventional treatment with hematopoietic cell transplantation ASCO/Lance Armstrong Foundation $unknown July 2, 2007
Childhood Cancer Survivor Study is an NCI-funded resource study whose primary goal is to study the late effects among a cohort of childhood cancer survivors NCI $unknown Dec. 1, 2005