Profile

Adrian M. Piliponsky, PhD

Adrian M. Piliponsky, PhD

Immunology

Children's Title: Principal Investigator

Academic Title: Assistant Professor, Department of Pediatrics, University of Washington; Adjunct Professor, Department of Pathology, University of Washington

Research Center: Center for Immunity and Immunotherapies

"I am passionate to come to the lab because I love what I do. Every day in the lab presents itself with new challenges and an infinite number of questions for which we usually have few or no answers. As a consequence of this, there is always work to be done and progress that ought to be celebrated and shared with the rest of the scientific community. I strongly believe that this is what research is about, and I am lucky to enjoy doing it every day."

Adrian Piliponsky, PhD, is a principal investigator within the Center for Immunity and Immunotherapeutics at Seattle Childrens Research Institute, and an assistant professor in the Department of Pediatrics at the University of Washington School of Medicine.

Dr. Piliponsky received his bachelors degree in Pharmacy from the University of Buenos Aires in Argentina. His passion for research eventually led him to The Hebrew University of Jerusalem in Israel where Dr. Piliponsky received his PhD. Under the mentorship of Francesca Levi-Schaffer, PhD, Dr. Piliponsky studied interactions of mast cells and eosinophils which are considered major players of allergies. With a desire to broaden his understanding of mast cells in vivousing mice with deficiencies in mast cells to study a variety of allergy and inflammatory disordersDr. Piliponsky took a post-doctoral position at Stanford University with Stephen J. Galli, MD, one of the lead researchers in the mast cell field.

Overview

Medical/Professional School

The Hebrew University, Hadassah Medical School, Jerusalem, Immunology

Fellowship

Stanford University , Stanford

Awards and Honors

Award Name Award Description Awarded By Award Date
Early Career Faculty Travel Grant Honor received to attend the American Association of Immunologists (AAI) 99th AAI Annual Meeting-IMMUNOLOGY 2012TM American Association of Immunologists (AAI) 2012
Travel Grant Honor received to attend The Fourth International Workshop on Signal Transduction in the Activation and Development of Mast Cells and NIH, Basophils at the Bethesda, MD The Aharon Katzir Center, Weizmann Institute of Science 2001
Travel Grant Honor received to attend the American Academy of Allergy, Asthma and Immunology (AAAAI) 56th Annual Meeting in New Orleans, LA. American Academy of Allergy, Asthma and Immunology (AAAAI) 2001
Superpharm Scholarship for PhD students at the School of Pharmacy The Hebrew University of Jerusalem, Israel 2000
Travel Grant Honor received to attend the 8th Euroconference on Apoptosis, Davos, Switzerland European Cell Death Organization (ECDO) 2000
Golda Meir Fellowship The Hebrew University of Jerusalem, Israel 1998 - 2001
National Institute of Drugs Fellowship Ministry of Health, Buenos Aires, Argentina 1995
Zuckerman Fellowship Hebrew University of Jerusalem, Israel. National Institute of Drugs Fellowship, Ministry of Health, Buenos Aires, Argentina. 1995 - 1998

Publications

  • Lai Y, Altemeier WA, Vandree J, Piliponsky AM, Johnson B, Appel CL, Frevert CW, Hyde DM, Ziegler SF, Smith DE, Henderson WR Jr, Gelb MH, Hallstrand TS
    Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33.
    The Journal of allergy and clinical immunology , 2013 Nov. 9
  • Lai Y, Altemeier WA, Vandree J, Piliponsky AM, Johnson B, Appel CL, Frevert CW, Hyde DM, Ziegler SF, Smith DE, Henderson WR Jr, Gelb MH, Hallstrand TS
    Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33.
    The Journal of allergy and clinical immunology , 2013 Nov. 9
  • Schäfer B, Piliponsky AM, Oka T, Song CH, Gerard NP, Gerard C, Tsai M, Kalesnikoff J, Galli SJ
    Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice.
    The Journal of allergy and clinical immunology , 2013 Feb. : 131(2)541-8.e1-9
  • Schäfer B, Piliponsky AM, Oka T, Song CH, Gerard NP, Gerard C, Tsai M, Kalesnikoff J, Galli SJ
    Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice.
    The Journal of allergy and clinical immunology , 2013 Feb. : 131(2)541-8.e1-9
  • Schäfer B, Piliponsky AM, Oka T, Song CH, Gerard NP, Gerard C, Tsai M, Kalesnikoff J, Galli SJ
    Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice.
    The Journal of allergy and clinical immunology , 2013 Feb. : 131(2)541-8.e1-9
  • Piliponsky AM, Chen CC, Rios EJ, Treuting PM, Lahiri A, Abrink M, Pejler G, Tsai M, Galli SJ
    The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis.
    The American journal of pathology , 2012 Sept. : 181(3)875-86
  • Piliponsky AM, Chen CC, Rios EJ, Treuting PM, Lahiri A, Abrink M, Pejler G, Tsai M, Galli SJ
    The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis.
    The American journal of pathology , 2012 Sept. : 181(3)875-86
  • Piliponsky AM, Chen CC, Rios EJ, Treuting PM, Lahiri A, Abrink M, Pejler G, Tsai M, Galli SJ
    The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis.
    The American journal of pathology , 2012 Sept. : 181(3)875-86
  • Lilla JN, Chen CC, Mukai K, BenBarak MJ, Franco CB, Kalesnikoff J, Yu M, Tsai M, Piliponsky AM, Galli SJ
    Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice.
    Blood , 2011 Dec. 22 : 118(26)6930-8
  • Lilla JN, Chen CC, Mukai K, BenBarak MJ, Franco CB, Kalesnikoff J, Yu M, Tsai M, Piliponsky AM, Galli SJ
    Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice.
    Blood , 2011 Dec. 22 : 118(26)6930-8
  • Lilla JN, Chen CC, Mukai K, BenBarak MJ, Franco CB, Kalesnikoff J, Yu M, Tsai M, Piliponsky AM, Galli SJ
    Reduced mast cell and basophil numbers and function in Cpa3-Cre; Mcl-1fl/fl mice.
    Blood , 2011 Dec. : 118(26)6930-8
  • Akahoshi M, Song CH, Piliponsky AM, Metz M, Guzzetta A, Abrink M, Schlenner SM, Feyerabend TB, Rodewald HR, Pejler G, Tsai M, Galli SJ
    Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice.
    The Journal of clinical investigation , 2011 Oct. : 121(10)4180-91
  • Akahoshi M, Song CH, Piliponsky AM, Metz M, Guzzetta A, Abrink M, Schlenner SM, Feyerabend TB, Rodewald HR, Pejler G, Tsai M, Galli SJ
    Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice.
    The Journal of clinical investigation , 2011 Oct. : 121(10)4180-91
  • Akahoshi M, Song CH, Piliponsky AM, Metz M, Guzzetta A, Abrink M, Schlenner SM, Feyerabend TB, Rodewald HR, Pejler G, Tsai M, Galli SJ
    Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice.
    The Journal of clinical investigation , 2011 Oct. : 121(10)4180-91
  • Piliponsky AM, Chen CC, Grimbaldeston MA, Burns-Guydish SM, Hardy J, Kalesnikoff J, Contag CH, Tsai M, Galli SJ
    Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice.
    The American journal of pathology , 2010 Feb. : 176(2)926-38
  • Piliponsky AM, Chen CC, Grimbaldeston MA, Burns-Guydish SM, Hardy J, Kalesnikoff J, Contag CH, Tsai M, Galli SJ
    Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice.
    The American journal of pathology , 2010 Feb. : 176(2)926-38
  • Piliponsky AM, Chen CC, Grimbaldeston MA, Burns-Guydish SM, Hardy J, Kalesnikoff J, Contag CH, Tsai M, Galli SJ
    Mast cell-derived TNF can exacerbate mortality during severe bacterial infections in C57BL/6-KitW-sh/W-sh mice.
    The American journal of pathology , 2010 Feb. : 176(2)926-38
  • Rios EJ, Piliponsky AM, Ra C, Kalesnikoff J, Galli SJ
    Rabaptin-5 regulates receptor expression and functional activation in mast cells.
    Blood , 2008 Nov. 15 : 112(10)4148-57
  • Rios EJ, Piliponsky AM, Ra C, Kalesnikoff J, Galli SJ
    Rabaptin-5 regulates receptor expression and functional activation in mast cells.
    Blood , 2008 Nov. 15 : 112(10)4148-57
  • Rios EJ, Piliponsky AM, Ra C, Kalesnikoff J, Galli SJ
    Rabaptin-5 regulates receptor expression and functional activation in mast cells.
    Blood , 2008 Nov. : 112(10)4148-57
  • Galli SJ, Tsai M, Piliponsky AM
    The development of allergic inflammation.
    Nature , 2008 July 24 : 454(7203)445-54
  • Galli SJ, Tsai M, Piliponsky AM
    The development of allergic inflammation.
    Nature , 2008 July 24 : 454(7203)445-54
  • Galli SJ, Tsai M, Piliponsky AM
    The development of allergic inflammation.
    Nature , 2008 July : 454(7203)445-54
  • Piliponsky AM, Chen CC, Nishimura T, Metz M, Rios EJ, Dobner PR, Wada E, Wada K, Zacharias S, Mohanasundaram UM, Faix JD, Abrink M, Pejler G, Pearl RG, Tsai M, Galli SJ
    Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis.
    Nature medicine , 2008 Apr, : 14(4)392-8
  • Piliponsky AM, Chen CC, Nishimura T, Metz M, Rios EJ, Dobner PR, Wada E, Wada K, Zacharias S, Mohanasundaram UM, Faix JD, Abrink M, Pejler G, Pearl RG, Tsai M, Galli SJ
    Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis.
    Nature medicine , 2008 Apr, : 14(4)392-8
  • Piliponsky AM, Chen CC, Nishimura T, Metz M, Rios EJ, Dobner PR, Wada E, Wada K, Zacharias S, Mohanasundaram UM, Faix JD, Abrink M, Pejler G, Pearl RG, Tsai M, Galli SJ
    Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis.
    Nature medicine , 2008 Apr, : 14(4)392-8
  • Metz M, Grimbaldeston MA, Nakae S, Piliponsky AM, Tsai M, Galli SJ
    Mast cells in the promotion and limitation of chronic inflammation.
    Immunological reviews , 2007 June : 217304-28
  • Metz M, Grimbaldeston MA, Nakae S, Piliponsky AM, Tsai M, Galli SJ
    Mast cells in the promotion and limitation of chronic inflammation.
    Immunological reviews , 2007 June : 217304-28
  • Metz M, Grimbaldeston MA, Nakae S, Piliponsky AM, Tsai M, Galli SJ
    Mast cells in the promotion and limitation of chronic inflammation.
    Immunological reviews , 2007 June : 217304-28
  • Nishimura T, Myles T, Piliponsky AM, Kao PN, Berry GJ, Leung LL
    Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo.
    Blood , 2007 Mar. 1 : 109(5)1992-7
  • Nishimura T, Myles T, Piliponsky AM, Kao PN, Berry GJ, Leung LL
    Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo.
    Blood , 2007 Mar. 1 : 109(5)1992-7
  • Nishimura T, Myles T, Piliponsky AM, Kao PN, Berry GJ, Leung LL
    Thrombin-activatable procarboxypeptidase B regulates activated complement C5a in vivo.
    Blood , 2007 Mar. : 109(5)1992-7
  • Metz M, Piliponsky AM, Chen CC, Lammel V, Abrink M, Pejler G, Tsai M, Galli SJ
    Mast cells can enhance resistance to snake and honeybee venoms.
    Science (New York, N.Y.) , 2006 July 28 : 313(5786)526-30
  • Metz M, Piliponsky AM, Chen CC, Lammel V, Abrink M, Pejler G, Tsai M, Galli SJ
    Mast cells can enhance resistance to snake and honeybee venoms.
    Science (New York, N.Y.) , 2006 July 28 : 313(5786)526-30
  • Metz M, Piliponsky AM, Chen CC, Lammel V, Abrink M, Pejler G, Tsai M, Galli SJ
    Mast cells can enhance resistance to snake and honeybee venoms.
    Science (New York, N.Y.) , 2006 July : 313(5786)526-30
  • Berent-Maoz B, Piliponsky AM, Daigle I, Simon HU, Levi-Schaffer F
    Human mast cells undergo TRAIL-induced apoptosis.
    Journal of immunology (Baltimore, Md. : 1950) , 2006 Feb. 15 : 176(4)2272-8
  • Berent-Maoz B, Piliponsky AM, Daigle I, Simon HU, Levi-Schaffer F
    Human mast cells undergo TRAIL-induced apoptosis.
    Journal of immunology (Baltimore, Md. : 1950) , 2006 Feb. 15 : 176(4)2272-8
  • Berent-Maoz B, Piliponsky AM, Daigle I, Simon HU, Levi-Schaffer F
    Human mast cells undergo TRAIL-induced apoptosis.
    Journal of immunology (Baltimore, Md. : 1950) , 2006 Feb. : 176(4)2272-8
  • Puxeddu I, Bader R, Piliponsky AM, Reich R, Levi-Schaffer F, Berkman N
    The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts.
    The Journal of allergy and clinical immunology , 2006 Jan. : 117(1)103-10
  • Puxeddu I, Bader R, Piliponsky AM, Reich R, Levi-Schaffer F, Berkman N
    The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts.
    The Journal of allergy and clinical immunology , 2006 Jan. : 117(1)103-10
  • Puxeddu I, Bader R, Piliponsky AM, Reich R, Levi-Schaffer F, Berkman N
    The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts.
    The Journal of allergy and clinical immunology , 2006 Jan. : 117(1)103-10
  • Matsuda K, Piliponsky AM, Iikura M, Nakae S, Wang EW, Dutta SM, Kawakami T, Tsai M, Galli SJ
    Monomeric IgE enhances human mast cell chemokine production: IL-4 augments and dexamethasone suppresses the response.
    The Journal of allergy and clinical immunology , 2005 Dec. : 116(6)1357-63
  • Matsuda K, Piliponsky AM, Iikura M, Nakae S, Wang EW, Dutta SM, Kawakami T, Tsai M, Galli SJ
    Monomeric IgE enhances human mast cell chemokine production: IL-4 augments and dexamethasone suppresses the response.
    The Journal of allergy and clinical immunology , 2005 Dec. : 116(6)1357-63
  • Matsuda K, Piliponsky AM, Iikura M, Nakae S, Wang EW, Dutta SM, Kawakami T, Tsai M, Galli SJ
    Monomeric IgE enhances human mast cell chemokine production: IL-4 augments and dexamethasone suppresses the response.
    The Journal of allergy and clinical immunology , 2005 Dec. : 116(6)1357-63
  • Grimbaldeston MA, Chen CC, Piliponsky AM, Tsai M, Tam SY, Galli SJ
    Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo.
    The American journal of pathology , 2005 Sept. : 167(3)835-48
  • Grimbaldeston MA, Chen CC, Piliponsky AM, Tsai M, Tam SY, Galli SJ
    Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo.
    The American journal of pathology , 2005 Sept. : 167(3)835-48
  • Grimbaldeston MA, Chen CC, Piliponsky AM, Tsai M, Tam SY, Galli SJ
    Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo.
    The American journal of pathology , 2005 Sept. : 167(3)835-48
  • Puxeddu I, Alian A, Piliponsky AM, Ribatti D, Panet A, Levi-Schaffer F
    Human peripheral blood eosinophils induce angiogenesis.
    The international journal of biochemistry & cell biology , 2005 Mar. : 37(3)628-36
  • Puxeddu I, Alian A, Piliponsky AM, Ribatti D, Panet A, Levi-Schaffer F
    Human peripheral blood eosinophils induce angiogenesis.
    The international journal of biochemistry & cell biology , 2005 Mar. : 37(3)628-36
  • Puxeddu I, Alian A, Piliponsky AM, Ribatti D, Panet A, Levi-Schaffer F
    Human peripheral blood eosinophils induce angiogenesis.
    The international journal of biochemistry & cell biology , 2005 Mar. : 37(3)628-36
  • Galli SJ, Kalesnikoff J, Grimbaldeston MA, Piliponsky AM, Williams CM, Tsai M
    Mast cells as "tunable" effector and immunoregulatory cells: recent advances.
    Annual review of immunology , 2005 : 23749-86
  • Galli SJ, Kalesnikoff J, Grimbaldeston MA, Piliponsky AM, Williams CM, Tsai M
    Mast cells as "tunable" effector and immunoregulatory cells: recent advances.
    Annual review of immunology , 2005 : 23749-86
  • Galli SJ, Kalesnikoff J, Grimbaldeston MA, Piliponsky AM, Williams CM, Tsai M
    Mast cells as "tunable" effector and immunoregulatory cells: recent advances.
    Annual review of immunology , 2005 : 23749-86
  • Maurer M, Wedemeyer J, Metz M, Piliponsky AM, Weller K, Chatterjea D, Clouthier DE, Yanagisawa MM, Tsai M, Galli SJ
    Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.
    Nature , 2004 Nov. 25 : 432(7016)512-6
  • Maurer M, Wedemeyer J, Metz M, Piliponsky AM, Weller K, Chatterjea D, Clouthier DE, Yanagisawa MM, Tsai M, Galli SJ
    Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.
    Nature , 2004 Nov. 25 : 432(7016)512-6
  • Maurer M, Wedemeyer J, Metz M, Piliponsky AM, Weller K, Chatterjea D, Clouthier DE, Yanagisawa MM, Tsai M, Galli SJ
    Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.
    Nature , 2004 Nov. : 432(7016)512-6
  • Levi-Schaffer F, Piliponsky AM
    Tryptase, a novel link between allergic inflammation and fibrosis.
    Trends in immunology , 2003 Apr, : 24(4)158-61
  • Levi-Schaffer F, Piliponsky AM
    Tryptase, a novel link between allergic inflammation and fibrosis.
    Trends in immunology , 2003 Apr, : 24(4)158-61
  • Levi-Schaffer F, Piliponsky AM
    Tryptase, a novel link between allergic inflammation and fibrosis.
    Trends in immunology , 2003 Apr, : 24(4)158-61
  • Piliponsky AM, Gleich GJ, Nagler A, Bar I, Levi-Schaffer F
    Non-IgE-dependent activation of human lung- and cord blood-derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor.
    Blood , 2003 Mar. 1 : 101(5)1898-904
  • Piliponsky AM, Gleich GJ, Nagler A, Bar I, Levi-Schaffer F
    Non-IgE-dependent activation of human lung- and cord blood-derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor.
    Blood , 2003 Mar. 1 : 101(5)1898-904
  • Piliponsky AM, Gleich GJ, Nagler A, Bar I, Levi-Schaffer F
    Non-IgE-dependent activation of human lung- and cord blood-derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor.
    Blood , 2003 Mar. : 101(5)1898-904
  • Adrian M. Piliponsky, PhD
    Mast cells as initiators and effectors of allergic inflammation. In: New Trends in Allergy V
    (Ring J, Behrendt H, Eds.), Springer-Verlag Berlin, Heidelberg 2003. , 2003
  • Piliponsky AM, Gleich GJ, Bar I, Levi-Schaffer F
    Effects of eosinophils on mast cells: a new pathway for the perpetuation of allergic inflammation.
    Molecular immunology , 2002 Sept. : 38(16-18)1369
  • Piliponsky AM, Gleich GJ, Bar I, Levi-Schaffer F
    Effects of eosinophils on mast cells: a new pathway for the perpetuation of allergic inflammation.
    Molecular immunology , 2002 Sept. : 38(16-18)1369
  • Piliponsky AM, Gleich GJ, Bar I, Levi-Schaffer F
    Effects of eosinophils on mast cells: a new pathway for the perpetuation of allergic inflammation.
    Molecular immunology , 2002 Sept. : 38(16-18)1369
  • Levi-Schaffer F, Micera A, Zamir E, Mechoulam H, Puxeddu I, Piliponsky AM, Aloe L, Pe'er J
    Nerve growth factor and eosinophils in inflamed juvenile conjunctival nevus.
    Investigative ophthalmology & visual science , 2002 June : 43(6)1850-6
  • Levi-Schaffer F, Micera A, Zamir E, Mechoulam H, Puxeddu I, Piliponsky AM, Aloe L, Pe'er J
    Nerve growth factor and eosinophils in inflamed juvenile conjunctival nevus.
    Investigative ophthalmology & visual science , 2002 June : 43(6)1850-6
  • Levi-Schaffer F, Micera A, Zamir E, Mechoulam H, Puxeddu I, Piliponsky AM, Aloe L, Pe'er J
    Nerve growth factor and eosinophils in inflamed juvenile conjunctival nevus.
    Investigative ophthalmology & visual science , 2002 June : 43(6)1850-6

Presentations

Presentations Title Event Location Date
Role of mast cells and mast cell proteases in innate immunity SRI International Menlo Park, CA Nov. 16, 2012
Mast cells and sepsis Department of Pathology, Sanford University Stanford, CA Nov. 15, 2012
Mast cells: from anaphylaxis to mastocytosis and beyond Pediatric Grand Rounds March 15, 2012
Role of mast cells in innate immunity Pulmonary Research Group, University of Washington University of Washington, Seattle, WA Jan. 23, 2012
TSLP promotes interleukin-3-independent basophil hematopoiesis and type 2 inflammation. Lung Division, University of Washington South Lake Union Sept. 29, 2011
Role of mast cells and mast cell proteases in innate immunity. Pediatric Inflammation Research Group, University of Washington South Lake Union Aug. 24, 2011
Mast cell chymase degrades TNF, limits inflammation, and promotes survival in a mouse model of sepsis 98th Annual Meeting of the American Association of Immunologists San Francisco, CA 2011
What good things do mast cells do and why do we need them? The Mastocytosis Society, Inc. 17th Annual Conference, Boston 2011

Research Funding

Grant Title Grantor Amount Award Date
1 R01 HL113351-01A1 NIH/NHLBI July 15, 2012 - April 30, 2017
12GRNT9680021 WSA/American Heart Association Jan. 1, 2012 - Dec. 31, 2013