Helen W. Karl, MD

Helen W. Karl, MD

Pain Medicine , Anesthesia

On staff since November 1990

Research Center: Center for Clinical and Translational Research

"I chose to become a pediatric anesthesiologist because (in 1980) I thought the subspecialty provided the greatest challenges and greatest rewards of all the areas of anesthesiology. We provide care for infants weighing less than a pound and for high school football players more than 200 times their size. Sometimes they are critically ill and would die without the operation; sometimes they are basically healthy, but frightened of an unusual environment. It is a privilege to care for these young people near the beginning of their lives."

I have been an academic pediatric anesthesiologist for 30 years. During that time, I have always taken care of patients, providing general and regional anesthesia and teaching the next generation of providers to do the same. I have had the good fortune to have a wide variety of additional parts to my job: inpatient pain management, clinical research, basic science research, writing and public speaking.

Pediatric anesthesiology and pain management have grown substantially, and we now have far more sophisticated understanding and equipment than we used to. It has been a pleasure to have been a small part of that growth; I look forward to ongoing learning and teaching.


Board Certification(s)

Pediatric Anesthesiology

Medical/Professional School

University of Virginia School of Medicine, Charlottesville


Anesthesiology, Hartford Hospital, Hartford


Anesthesiology, Children's Hospital of Philadelphia, Philadelphia
Pulmonary Disease, Penn State University Hospital - Milton S Hershey College of Medicine, Hershey

Research Focus Area

Translational Research


  • Stogicza, A, Racz E, Karl HW, Trescot AM
    Bolus Versus Continuous Infusions for Epidural Blocks: A Cadaveric Study.
  • Moesker, A.A., Karl, H.W. Trescot, A. M
    Treatment of phantom limb pain by cryoneurolysis of the amputated nerve
    Pain Practice , 2014 : 14(1)52-6
  • Karl, H., Tyler, D. C., Miser, A. W.
    Controlled trial of morphine vs. hydromorphone for patient-controlled analgesia in children with postoperative pain
    Pain Medicine , 2012 : 131658-1659
  • Coté CJ, Cohen IT, Suresh S, Rabb M, Rose JB, Weldon BC, Davis PJ, Bikhazi GB, Karl HW, Hummer KA, Hannallah RS, Khoo KC, Collins P
    A comparison of three doses of a commercially prepared oral midazolam syrup in children.
    11772797 Anesthesia and analgesia , 2002 Jan. : 37-43, table of contents
  • Trescot, A. M., Brown, M. N., Karl, H.
    Infrapatellar Saphenous Neuralgia: Diagnosis and Treatment
    Pain Physician
  • Moesker, A. A., Karl, H., Trescot, A. M.
    Treatment of Phantom Limb Pain By Cryoneurolysis of the Amputated Nerve
    Pain Practice
  • Karl, H., Law, E., McGinn, K.
    Pain in Infants, Children, and Adolescents
    L Manchikanti, P Christo, A Trescot, and J Giordano (Ed.), Comprehensive Pain Medicine and Interventional Pain Management Board Review


Presentations Title Event Location Date
Development of Pain Systems and Neonatal Pain Management American Society of Interventional Pain Physicians Review Course St.Louis, MO Aug. 2013
Pain in Infants, Children, and Adolescents American Society of Interventional Pain Physicians Review Course St.Louis, MO Aug. 2013
Bolus Versus Continuous Infusions for Epidural Blocks: A Cadaveric Study University of Washington, Academic evening University of Washington, Seattle, WA May 2013