Skip to main content

Search
Research

Research Labs

|

As one of the nation’s top five pediatric research centers, Seattle Children’s Research Institute has pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies, and made other major contributions to pediatric medicine. With more than 350 investigators, our labs and research groups are working toward the next wave of discoveries for hundreds of diseases and disorders.

Alphabetical Listing of Research Labs

NameResearch CenterDisease or ConditionDescription
Christakis Lab Center for Child Health, Behavior and DevelopmentAttention problems, behavioral disordersThe Christakis lab investigates the impact that early experiences, including television exposure, have on children’s cognitive, social and behavioral development.
Cox LabCenter for Developmental Biology and Regenerative MedicineCleft lip and palate, craniosyntosisThe Cox lab investigates molecular and developmental causes of common craniofacial malformations, such cleft lip/palate and craniosynostosis.
Craniofacial Outcomes Research and Epidemiology (CORE) Group Center for Clinical and Translational ResearchCraniofacial microsomia, 22q11.2 deletion syndrome and other craniofacial conditionsThe CORE group collaborates to understand the epidemiology of craniofacial conditions and to identify treatments to improve outcomes for those conditions.
Cunningham Lab Center for Developmental Biology and Regenerative MedicineCraniosynostosis and other craniofacial conditionsThe Cunningham lab investigates the fundamental mechanisms behind craniosynostosis and other malformations, pursuing discoveries that improve patient care.
Evans Lab Center for Clinical and Translational ResearchRobin sequence and other craniofacial conditionsThe Evans lab investigates sleep and breathing in children born with craniofacial conditions, with the goal of improving outcomes.
Frenkel Lab Center for Childhood Infections and Prematurity ResearchHIVThe Frenkel lab is working to prevent mother-infant HIV transmission by studying the mechanisms behind that transmission; developing practical, affordable ways to prevent it; and developing tests and treatments for drug-resistant HIV.
Heike Lab Center for Clinical and Translational ResearchCraniofacial microsomia, 22q11.2 deletion syndrome and other craniofacial conditionsThe Heike lab aims to improve care by unraveling the causes of craniofacial conditions, developing new evaluation tools and assessing treatment outcomes.
Hevner Lab Center for Integrative Brain ResearchLissencephaly and other neurodevelopmental disordersThe Hevner lab studies transcription factors and neurogenesis, the process by which neurons are formed in the developing brain. Neurogenesis holds great scientific and medical interest because of its significance for human brain development and disease.
Hing Studies Center for Developmental Biology and Regenerative MedicineCleft lip and palate, midface hypoplasia, craniosynostosis and other craniofacial conditionsDr. Anne V. Hing investigates the genetic causes of craniofacial disorders and specializes in recruiting patients for studies.
Jensen Lab Center for Childhood Cancer ResearchLeukemia, lymphoma, neuroblastomaThe Jensen lab is pursuing innovative treatments that reprogram a child’s defense system to eliminate cancer cells, without chemotherapy or radiation – or their debilitating side effects.
Katzenellenbogen Lab Center for Childhood Infections and Prematurity ResearchHuman papillomavirus (HPV)The Katzenellenbogen lab studies the mechanism by which human papillomavirus (HPV) activates telomerase, an enzyme that is activated in cancers, in order to understand how HPV drives cells to become malignant.
Kolker Lab Center for Developmental TherapeuticsBioinformatics and High-Throughput Analysis LaboratoryThe Kolker lab focuses on bioinformatics, health informatics and integrative analyses. They use high-throughput technologies to examine and model molecular mechanisms of biological processes.
Luquetti Lab Center for Developmental Biology and Regenerative MedicineMicrotia, craniofacial microsomia and other craniofacial conditionsThe Luquetti lab studies the genetics and epidemiology of craniofacial malformations, with the goal of identifying their causes and developing research methods that can apply to a variety of birth defects.
Majesky Lab Center for Developmental Biology and Regenerative MedicineCongenital heart defects and other cardiac abnormalitiesThe Majesky lab is studying the embryonic development of the heart and vascular system, with the goal of developing cell-based therapies for congenital heart defects and other cardiac abnormalities.
McCarty Lab Center for Child Health, Behavior and DevelopmentBehavioral health among adolescentsThe McCarty lab's mission is to improve the emotional and behavioral health of children and adolescents through enhanced scientific understanding, promoting social-emotional competencies and disseminating evidence-based treatments.
Millen Lab Center for Integrative Brain ResearchDandy-Walker malformation and other cerebellar malformationsThe Millen lab studies the genetic and developmental basis of structural birth defects of the brain both in humans and mice.
Morgan–Sedensky Lab     Center for Developmental TherapeuticsMitochondrial disease, aging, C. elegans genetics, anesthetic sensitivityThe Morgan–Sedensky Lab investigates the mechanism of action of volatile anesthetics, translational studies to understand mitochondrial disease and aging.
Myers Lab Center for Child Health, Behavior and Development Telemental healthThe Myers lab is focused on providing evidence-based mental healthcare services through telemental health to rectify current disparities in access to mental healthcare.
Neonatal Respiratory Support Technologies (NeoRest) Center for Developmental TherapeuticsInfant respiratory distressThe NeoRest team is developing simple, affordable technologies that provide respiratory care to infants in developing countries, for a fraction of the cost of conventional ventilators.
Ojemann Lab Center for Integrative Brain ResearchEpilepsyThe Ojemann lab is interested in using electrocorticography (ECoG), which is used for long-term clinical monitoring of epilepsy patients, to answer basic neuroscience questions as well as to develop tools for clinical and rehabilitative applications.
Palermo Lab Center for Child Health, Behavior and DevelopmentChronic painThe Palermo lab studies pain in children, particularly the interrelationships of pain, sleep and behavioral/psychological factors; psychological and family treatments for pediatric chronic pain management; technological and Internet-based innovations for pain assessment; and health risk factors and chronic pain.
Portman Research Group Center for Developmental TherapeuticsHeart defects, Kawasaki diseaseThe Portman Research Group discovers ways to protect children’s hearts from damage related to surgery, and leads major research on Kawasaki disease.
Rajagopal Lab Center for Childhood Infections and Prematurity ResearchStreptococcus, Staphylococcus aureusThe Rajagopal lab uses genetic, molecular, biochemical and proteomic approaches to study infectious diseases caused by bacteria. The human pathogens that we study are Group B Streptococcus and Staphylococcus aureus.
Ramirez Lab Center for Integrative Brain ResearchEpilepsy, sudden infant death syndrome (SIDS), sleep apnea and other neurological disordersThe Ramirez lab is making fundamental advances in our understanding of the brain and building toward potential cures for sudden infant death syndrome (SIDS), epilepsy and other disorders. The lab is currently focusing on how periods of hypoxia, such as those experienced by sleep apnea patients, alter the neuronal network that controls respiration.
Saelens Lab Center for Child Health, Behavior and DevelopmentPediatric overweightThe Saelens lab investigates how environmental factors influence physical activity, eating behaviors and the psychosocial factors that influence individual choice for weight-related behaviors.
Speltz LabCenter for Child Health, Behavior and DevelopmentCleft lip and palate, single-suture craniosynostosis, deformational plagiocephaly, hemifacial microsomia and other craniofacial disordersThe Speltz lab focuses on the neurobehavioral development of children with craniofacial disorders, including cleft lip and palate, single-suture craniosynostosis, deformational plagiocephaly and hemifacial microsomia.
Webb LabCenter for Childhood Infections and Prematurity ResearchAutism, fragile X, developmental delay and other developmental disabilitiesThe Webb lab studies how infants, children and adults learn about their environment, and how that learning is impacted by developmental disruptions.
Weissman Lab Center for Childhood Infections and Prematurity ResearchAntibiotic-resistant infectionsThe Weissman lab studies how antibiotic-resistant bacteria emerge and develops innovative ways to identify and monitor them.

Looking for a Researcher?

Looking for a researcher?

Name: