| Name | Research Center | Disease or Condition | Description |
|---|
| Christakis Lab | Center for Child Health, Behavior and Development | Attention problems, behavioral disorders | The Christakis lab investigates the impact that early experiences, including television exposure, have on children’s cognitive, social and behavioral development. |
| Cox Lab | Center for Tissue and Cell Sciences | Cleft lip and palate, craniosyntosis | The Cox lab investigates molecular and developmental causes of common craniofacial malformations, such cleft lip/palate and craniosynostosis. |
| Cunningham Lab | Center for Tissue and Cell Sciences | Syndromic craniosynostosis, single suture craniosynostosis | The Cunningham lab uses animal models and human cell lines to study the molecular and developmental pathogenesis of human malformations. Their major field of study is the pathogenesis of craniosynostosis. |
| Frenkel Lab | Center for Childhood Infections and Prematurity Research | HIV | The Frenkel lab is working to prevent mother-infant HIV transmission by studying the mechanisms behind that transmission; developing practical, affordable ways to prevent it; and developing tests and treatments for drug-resistant HIV. |
| Hevner Lab | Center for Integrative Brain Research | Lissencephaly and other neurodevelopmental disorders | The Hevner lab studies transcription factors and neurogenesis, the process by which neurons are formed in the developing brain. Neurogenesis holds great scientific and medical interest because of its significance for human brain development and disease. |
| Jensen Lab | Center for Childhood Cancer Research | Leukemia, lymphoma, neuroblastoma | The Jensen lab is pursuing innovative treatments that reprogram a child’s defense system to eliminate cancer cells, without chemotherapy or radiation – or their debilitating side effects. |
| Katzenellenbogen Lab | Center for Childhood Infections and Prematurity Research | Human papillomavirus (HPV) | The Katzenellenbogen lab studies the mechanism by which human papillomavirus (HPV) activates telomerase, an enzyme that is activated in cancers, in order to understand how HPV drives cells to become malignant. |
| Kolker Lab | Center for Developmental Therapeutics | Bioinformatics and High-Throughput Analysis Laboratory | The Kolker lab focuses on bioinformatics, health informatics and integrative analyses. They use high-throughput technologies to examine and model molecular mechanisms of biological processes. |
| Majesky Lab | Center for Tissue and Cell Sciences | Congenital heart defects and other cardiac abnormalities | The Majesky lab is studying the embryonic development of the heart and vascular system, with the goal of developing cell-based therapies for congenital heart defects and other cardiac abnormalities. |
| Millen Lab | Center for Integrative Brain Research | Dandy-Walker malformation and other cerebellar malformations | The Millen lab studies the genetic and developmental basis of structural birth defects of the brain both in humans and mice. |
| Myers Lab | Center for Child Health, Behavior and Development | Telemental health | The Myers lab is focused on providing evidence-based mental healthcare services through telemental health to rectify current disparities in access to mental healthcare. |
| Neonatal Respiratory Support Technologies (NeoRest) | Center for Developmental Therapeutics | Infant respiratory distress | The NeoRest team is developing simple, affordable technologies that provide respiratory care to infants in developing countries, for a fraction of the cost of conventional ventilators. |
| Ojemann Lab | Center for Integrative Brain Research | Epilepsy | The Ojemann lab is interested in using electrocorticography (ECoG), which is used for long-term clinical monitoring of epilepsy patients, to answer basic neuroscience questions as well as to develop tools for clinical and rehabilitative applications. |
| Palermo Lab | Center for Child Health, Behavior and Development | Chronic pain | The Palermo lab studies pain in children, particularly the interrelationships of pain, sleep and behavioral/psychological factors; psychological and family treatments for pediatric chronic pain management; technological and Internet-based innovations for pain assessment; and health risk factors and chronic pain. |
| Rajagopal Lab | Center for Childhood Infections and Prematurity Research | Streptococcus, Staphylococcus aureus | The Rajagopal lab uses genetic, molecular, biochemical and proteomic approaches to study infectious diseases caused by bacteria. The human pathogens that we study are Group B Streptococcus and Staphylococcus aureus. |
| Ramirez Lab | Center for Integrative Brain Research | Epilepsy, sudden infant death syndrome (SIDS), sleep apnea and other neurological disorders | The Ramirez lab is making fundamental advances in our understanding of the brain and building toward potential cures for sudden infant death syndrome (SIDS), epilepsy and other disorders. The lab is currently focusing on how periods of hypoxia, such as those experienced by sleep apnea patients, alter the neuronal network that controls respiration. |
| Saelens Lab | Center for Child Health, Behavior and Development | Pediatric overweight | The Saelens lab investigates how environmental factors influence physical activity, eating behaviors and the psychosocial factors that influence individual choice for weight-related behaviors. |
| Speltz Lab | Center for Child Health, Behavior and Development | Cleft lip and palate, single-suture craniosynostosis, deformational plagiocephaly, hemifacial microsomia and other craniofacial disorders | The Speltz lab focuses on the neurobehavioral development of children with craniofacial disorders, including cleft lip and palate, single-suture craniosynostosis, deformational plagiocephaly and hemifacial microsomia. |
| Webb Lab | Center for Childhood Infections and Prematurity Research | Autism, fragile X, developmental delay and other developmental disabilities | The Webb lab studies how infants, children and adults learn about their environment, and how that learning is impacted by developmental disruptions. |
| Weissman Lab | Center for Childhood Infections and Prematurity Research | E. coli, early-onset sepsis | The Weissman lab studies Escherichia coli and antibiotic resistance with the goal of improving treatment for early-onset sepsis and understanding how “superbugs” emerge and spread. |