Featured Research

Innovations in enzyme development made by the Scharenberg and Rawlings labs and their partners at the University of Washington and Fred Hutchinson Cancer Research Center move researchers closer to making precision gene manipulation a therapeutic reality.
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Results from international clinical trials led by Dr. Bonnie Ramsay signal a breakthrough in treatment for cystic fibrosis.
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Dr. Jonathan Perkins' use of a blood-pressure medicine to treat hemangiomas has reduced the need for surgery by 75%. Now he's working to understand why the drug works.
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Drs. Scott Baker and Eric Chow are on a mission to help survivors of childhood cancer live their healthiest possible lives.
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Dr. Colleen Delaney's pioneering approach to accelerating white blood cell recovery moves to Phase II trials.
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A new kind of hydrocephalus shunt being developed by Dr. Sam Browd incorporates the latest technologies and promises to dramatically reduce failure rates.
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Seattle Children’s lands a major NIH grant to take a multi-pronged look at how the virus that causes Kaposi’s sarcoma spreads and turns cancerous.
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Dr. Dimitri Christakis has devoted his career to investigating how media exposure impacts children and helping parents take control of their family's media habits.
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Dr. Janet Englund played a dual role in the nation's response to the H1N1 pandemic. She helped determine priority groups who would get the vaccine earliest and also helped test the vaccine's safety and potential effectiveness in children.
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One thrust of Dr. Jack McClellan's research — studying the safety and usefulness of current antipsychotic medications — points to the need for better therapies. The other — searching for genetic causes of schizophrenia — could someday lead to more effective diagnostic and treatment strategies for that disease.
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Dr. Carol Wallace is investigating whether aggressive treatment within a year of onset will result in better outcomes for patients with juvenile idiopathic arthritis (JIA) by halting progression of the disease..
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Dr. Robert Hevner focuses on contributing important discoveries to the essential stockpile of knowledge he hopes will further the ultimate goal of neuroregeneration — regrowth and repair of neurons.
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Recent outbreaks of respiratory viruses highlight the need for quick diagnosis to prevent the spread of disease. However, laboratories are still only able to detect virus in about 50% of samples. Tim Rose, PhD, wants to increase that detection rate.
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Today, with more than 15% of American children considered obese, it's feared that weight-related diseases will reach epidemic levels as these youth reach adulthood. Two Seattle Children's researchers are working to reverse this trend.
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Dr. Anne Stevens, a physician-scientist at Seattle Children's, believes maternal cells — which are transported to a fetus during pregnancy and persist through a child's lifetime — might play a role in pediatric lupus.
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Dr. Daniel Rubens follows his intuition and opens a new door that may reveal a secret to SIDS.
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There appears to be some relationship between craniosynostosis and neurodevelopment, but the nature of that relationship is currently unknown. Dr. Matt Speltz hopes to find the answer to that relationship.
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Dr. Andrew Scharenberg is working on an innovative approach to gene therapy called gene repair, in which proteins will cut defective sequences of DNA within a gene and cause them to be replaced with corrected sequences.
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On the road to a healthy future, information can be the best medicine. That's the premise behind health outcomes research and the work of Dr. Dimitri Christakis.
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Dr. Dave Rawlings is looking for ways to correct primary immune deficiency diseases (PIDD).
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Dr. Danielle Zerr visits Jordan Keen four days after his stem cell transplant to fight acute lymphocytic leukemia.
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Dr. Hans Ochs is looking at the connection between immune deficiencies and genes.
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