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Mark A. Stein, PhD, ABPP

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Mark A. Stein, PhD, ABPP

Psychiatry and Behavioral Health, Pediatrics-Inpatient

On staff since April 2013

Research Center: Center for Child Health, Behavior and Development

"I first became interested in ADHD and stimulant medications when I was a camp counselor of 12, 7-year old boys. One of my exuberant campers, would chase butterflies but would not play kickball or follow directions. One day, he seemed very different. That day, he followed the rules of the game, and even scored a run. His personality was different also, more serious and quiet , and he had no appetite for lunch. Having spent the last 30 years studying ADHD treatment effects, both positive and negative, I want to spend the next 10 learning how to sequence and deliver individualized treatments for the impairments related to ADHD and to train others who see children, adolescents, and adults in managing this commonly misunderstood disorder."

Recommendations

AnnaChicago, Il04.29.13
Dr. Stein is equal parts compassionate and knowledgeable. He is very comfortable chatting with children in an age appropriate manner, and he is equally adroit in communicating with parents. There is the old saying, about loss and gain. When Dr. Stein (understandably went to Seattle Children's) Chicago's loss, Seattle's gain.
Recommend Dr. Mark Stein

Overview

Board Certification(s)
Clinical Psychology
Medical/Professional School
Southern Illinois University - Carbondale, Carbondale
Fellowship
MacLean Center for Clinical Medical Ethics, Chicago
Lab URL

http://www.seattlechildrens.org/about/stories/improving-treatment-for-ADHD/

Awards and Honors

Award NameAward DescriptionAwarded ByAward Date
FellowSociety of Clinical Child and Adolescent Psychology 2001
Fellowin recognition of outstanding and unusual contributions to the science and profession of psychologyAmerican Psychological Association 2000

Publications

Differential impact of methylphenidate and atomoxetine on sustained attention in youth with attention-deficit/hyperactivity disorder.
Journal of child psychology and psychiatry, and allied disciplines , 2014 Jun 19
Dopamine transporter genotype and stimulant dose-response in youth with attention-deficit/hyperactivity disorder.
Journal of child and adolescent psychopharmacology , 2014 Jun: 24(5)238-44
Future research directions in sleep and ADHD: report of a consensus working group.
Journal of attention disorders , 2013 Oct: 17(7)550-64
Randomized, double-blind trial of guanfacine extended release in children with attention-deficit/hyperactivity disorder: morning or evening administration.
Journal of the American Academy of Child and Adolescent Psychiatry , 2013 Sep: 52(9)921-30
Assessment and management of sleep problems in youths with attention-deficit/hyperactivity disorder.
Journal of the American Academy of Child and Adolescent Psychiatry , 2013 Aug: 52(8)784-96
The War on ADHD
Nature Medicine , 2013: 19(12)1366
Sleep problems and interventions in preschoolers with ADHD
ADHD in Preschool Children:Assessment and Treatment , 2013
Dimensionality, hierarchical structure, age generalizability, and criterion validity of the GAIN's Behavioral Complexity Scale.
Psychological assessment , 2012 Dec: 24(4)913-24
A translational approach to evaluate the efficacy and safety of the novel AMPA receptor positive allosteric modulator org 26576 in adult attention-deficit/hyperactivity disorder.
Biological psychiatry , 2012 Dec 1: 72(11)971-7
Pharmacotherapy for parents with attention-deficit hyperactivity disorder (ADHD): impact on maternal ADHD and parenting.
CNS drugs , 2012 Sep 1: 26(9)725-32
ADHD Treatments, Sleep, and Sleep Problems: Complex Associations
Neurotherapeutics , 2012: 9509-517
Variable sleep schedules and outcomes in children with psychopathological problems: preliminary observations.
Nature and science of sleep , 2012: 49-17
Dose effects and comparative effectiveness of extended release dexmethylphenidate and mixed amphetamine salts.
Journal of child and adolescent psychopharmacology , 2011 Dec: 21(6)581-8
Pharmacogenetic predictors of methylphenidate dose-response in attention-deficit/hyperactivity disorder.
Journal of the American Academy of Child and Adolescent Psychiatry , 2011 Nov: 50(11)1129-1139.e2
Effect of dopamine transporter genotype on caudate volume in childhood ADHD and controls.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics , 2011 Jan: 156B(1)28-35
Neural response to working memory load varies by dopamine transporter genotype in children.
NeuroImage , 2010 Nov 15: 53(3)970-7
Dose-response characteristics in adolescents with attention-deficit/hyperactivity disorder treated with OROS methylphenidate in a 4-week, open-label, dose-titration study.
Journal of child and adolescent psychopharmacology , 2010 Jun: 20(3)187-96
Increased cortisol after stress is associated with variability in response time in ADHD children.
Yonsei medical journal , 2010 Mar: 51(2)206-11
Progress and promise of attention-deficit hyperactivity disorder pharmacogenetics.
CNS drugs , 2010 Feb: 24(2)99-117
Progress and promise of attention-deficit hyperactivity disorder pharmacogenetics.
CNS drugs , 2010 Feb: 24(2)99-117
Effects of maternal stimulant medication on observed parenting in mother-child dyads with attention-deficit/hyperactivity disorder.
Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 , 2010: 39(4)581-7
Effects of maternal stimulant medication on observed parenting in mother-child dyads with attention-deficit/hyperactivity disorder.
Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 , 2010: 39(4)581-7
Novel and functional norepinephrine transporter protein variants identified in attention-deficit hyperactivity disorder.
Neuropharmacology , 2009 Dec: 57(7-8)694-701
Choline transporter gene variation is associated with attention-deficit hyperactivity disorder.
Journal of neurodevelopmental disorders , 2009 Dec: 1(4)252-63
Novel and functional norepinephrine transporter protein variants identified in attention-deficit hyperactivity disorder.
Neuropharmacology , 2009 Dec: 57(7-8)694-701
Dopamine transporter genotype and stimulant side effect factors in youth diagnosed with attention-deficit/hyperactivity disorder.
Journal of child and adolescent psychopharmacology , 2009 Jun: 19(3)233-9
Dopamine transporter genotype and stimulant side effect factors in youth diagnosed with attention-deficit/hyperactivity disorder.
Journal of child and adolescent psychopharmacology , 2009 Jun: 19(3)233-9
The impact of individual and methodological factors in the variability of response to methylphenidate in ADHD pharmacogenetic studies from four different continents.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics , 2008 Dec 5: 147B(8)1419-24
Efficacy of osmotic-release oral system (OROS) methylphenidate for mothers with attention-deficit/hyperactivity disorder (ADHD): preliminary report of effects on ADHD symptoms and parenting.
The Journal of clinical psychiatry , 2008 Dec: 69(12)1938-47
Medical mimics and differential diagnosis in adult ADHD.
CNS spectrums , 2008 Oct: 13(10 Suppl 15)14-6
Longitudinal study of new eye lesions in children with toxoplasmosis who were not treated during the first year of life.
American journal of ophthalmology , 2008 Sep: 146(3)375-384
Treating adult ADHD with stimulants.
CNS spectrums , 2008 Sep: 13(9 Suppl 13)8-11
Maternal depression predicts maternal use of corporal punishment in children with attention-deficit/hyperactivity disorder.
Yonsei medical journal , 2008 Aug 30: 49(4)573-80
Toxoplasmosis-associated neovascular lesions treated successfully with ranibizumab and antiparasitic therapy.
Archives of ophthalmology , 2008 Aug: 126(8)1152-6
Impairment associated with adult ADHD.
CNS spectrums , 2008 Aug: 13(8 Suppl 12)9-11
The pharmacogenomic era: promise for personalizing attention deficit hyperactivity disorder therapy.
Child and adolescent psychiatric clinics of North America , 2008 Apr: 17(2)475-90, xi-xii
Cortisol is inversely correlated with aggression for those boys with attention deficit hyperactivity disorder who retain their reactivity to stress.
Psychiatry research , 2007 Sep 30: 153(1)55-60
The complexity of ADHD: diagnosis and treatment of the adult patient with comorbidities.
CNS spectrums , 2007 Aug: 12(8 Suppl 12)1-14; quiz 15-6
The complexity of ADHD: diagnosis and treatment of the adult patient with comorbidities.
CNS spectrums , 2007 Aug: 12(8 Suppl 12)1-14; quiz 15-6
Plasma homovanillic acid correlates inversely with history of learning problems in healthy volunteer and personality disordered subjects.
Psychiatry research , 2007 Jan 15: 149(1-3)297-302
Plasma homovanillic acid correlates inversely with history of learning problems in healthy volunteer and personality disordered subjects.
Psychiatry research , 2007 Jan 15: 149(1-3)297-302
Impact of visual impairment on measures of cognitive function for children with congenital toxoplasmosis: implications for compensatory intervention strategies.
Pediatrics , 2006 Aug: 118(2)e379-90
Impact of visual impairment on measures of cognitive function for children with congenital toxoplasmosis: implications for compensatory intervention strategies.
Pediatrics , 2006 Aug: 118(2)e379-90
Once-daily OROS methylphenidate is safe and well tolerated in adolescents with attention-deficit/hyperactivity disorder.
Journal of child and adolescent psychopharmacology , 2006 Jun: 16(3)351-6
Multisite controlled study of OROS methylphenidate in the treatment of adolescents with attention-deficit/hyperactivity disorder.
Archives of pediatrics & adolescent medicine , 2006 Jan: 160(1)82-90
Sequence variation in the human dopamine transporter gene in children with attention deficit hyperactivity disorder.
Neuropharmacology , 2005 Nov: 49(6)724-36
ADHD treatment with once-daily OROS methylphenidate: final results from a long-term open-label study.
Journal of the American Academy of Child and Adolescent Psychiatry , 2005 Oct: 44(10)1015-23
Dopamine transporter genotype and methylphenidate dose response in children with ADHD.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology , 2005 Jul: 30(7)1374-82
Innovations in attention-deficit/hyperactivity disorder pharmacotherapy: long-acting stimulant and nonstimulant treatments.
The American journal of managed care , 2004 Jul: 10(4 Suppl)S89-98
A dose-response study of OROS methylphenidate in children with attention-deficit/hyperactivity disorder.
Pediatrics , 2003 Nov: 112(5)e404
A dose-response study of OROS methylphenidate in children with attention-deficit/hyperactivity disorder.
Pediatrics , 2003 Nov: 112(5)e404
ADHD treatment with once-daily OROS methylphenidate: interim 12-month results from a long-term open-label study.
Journal of the American Academy of Child and Adolescent Psychiatry , 2003 Apr: 42(4)424-33
Thyroid function tests and neurocognitive functioning in children referred for attention deficit/hyperactivity disorder.
Psychoneuroendocrinology , 2003 Apr: 28(3)304-16
ADHD treatment with once-daily OROS methylphenidate: interim 12-month results from a long-term open-label study.
Journal of the American Academy of Child and Adolescent Psychiatry , 2003 Apr: 42(4)424-33
Thyroid function tests and neurocognitive functioning in children referred for attention deficit/hyperactivity disorder.
Psychoneuroendocrinology , 2003 Apr: 28(3)304-16
Sex differences in young children who meet criteria for attention deficit hyperactivity disorder.
Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 , 2002 Dec: 31(4)453-64
Sex differences in young children who meet criteria for attention deficit hyperactivity disorder.
Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 , 2002 Dec: 31(4)453-64
Can stimulant rebound mimic pediatric bipolar disorder?
Journal of child and adolescent psychopharmacology , 2002 Spring: 12(1)63-7
Can stimulant rebound mimic pediatric bipolar disorder?
Journal of child and adolescent psychopharmacology , 2002 Spring: 12(1)63-7
Attention Deficit Disorder and Hyperactivity in Children and Adults ( 2nd Edition). Marcel Dekker: New York. 736pp.
, 1999
Adaptive skills dysfunction in ADD and ADHD Children.
Journal of Child Psychology and Psychiatry , 1995: 36663-70
Mimics of ADHD: Medical and Neurological.
ADHD in Children, Adolescents and Adults. ,

Presentations

Presentations TitleEventLocationDate
Effects of Dosage on Sleep Duration during Stimulant Treatmenbt for ADHDCanadian Paediatric SocietyMontreal 2014
Evaluating Research Start (Study and Trial Accelerator for Research Teams)NIH Workshop on Enrollment and Retention of Participants in Clinical TriaLSBethesda,Maryland 2014
Making Sense of ADHD Pharmacogenetics: DAT1, Ancestral Markers, Dose, and Study Methodology. SOciety of Biological PsychiatrySan Francisco, CaMay 2013
How new ADHD treatment studies can inform practice? WOrld Congress on ADHDTel Aviv, IsraelApril 2013
Stein M, White C, Enright G, Dammerman R. Morning or Evening Dosing of Guanfacine Extended Release: Remission of Pediatric ADHD as Assessed by Clinical Global Impressions. Pediatric Academic Society (Society for Pediatric ResearchBoston, MA.May 2012
Pharmacogenomics and Personalized ADHD Treatment: Are we there yet? Johns Hoplins Spectrum Conference on ADHDBaltimore, MDApril 2012

Primary Office

Seattle Children's
OA.5.154 - Child Psychiatry
4800 Sand Point Way NE
Seattle, WA 98105
206-987-2164

Additional Offices

Seattle Children's at Overlake
1135 116th Ave NE Suite 400
Bellevue , WA 98004
425-454-4644

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