Current Research Studies

ADHD – Polygenetic Risk Score and ADHD Treatment Response (PRAT)

What is the goal of this study?

We want to track your child’s response to ADHD treatment and determine if genetic risk affects their response. This research seeks to find out if the number of genes someone has that are thought to be related to Attention Deficit Hypertension Disorder (ADHD) can predict their response to treatment of ADHD. We also want to find out whether a parent’s genetic risk for ADHD and symptoms of ADHD impact their child’s response to ADHD treatment.

Who can join the study?

This study may be a good fit for children who:

  • Are between the ages of 5 to 12 years old.
  • Have been diagnosed with ADHD.
  • Are about to start ADHD treatment.
  • Have a biological parent who would like help in evaluating how their child responds to ADHD treatment.


What will happen if my child takes part in this study?

If you choose to participate in this study:

  • You and your child (and a second parent if they’d like to participate) will give saliva samples for genetic analysis.
  • You will complete a survey and interview about you and your child’s ADHD at two different times.
  • You will receive a summary from study doctors about your child’s ADHD.
  • Study doctors can provide ADHD treatment recommendations to your and your child’s doctor(s).

Who can I contact for more information?

To learn more, call 206-884-1113 or email the study team

Study Location(s):

Seattle Children's main hospital campus

Principal Investigator:

Dr. Mark Stein
Research Center: Center for Child Health, Behavior and Development