Current Research Studies

Cancer – PNOC 014: A Phase I/II and Target Validation Study of TAK-580 (MLN2480) for Children with Low-Grade Gliomas and Other RAS/RAF/MEK/ERK Pathway Activated Tumor

Condition or Therapy:

Low-grade glioma, TAK-580


Cancer and blood disorders

What is the goal of this study?

The goal of this study is to assess how the drug TAK-580 responds in patients with low-grade glioma.

Who can join the study?

This study may be a good fit for children and young adults who:

  • Are between 1 and 18 years old and
  • Have low-grade glioma

What will happen if my child takes part in this study?

You can read more about this study on

Who can I contact for more information?

To learn more, call 206-987-2106 or email the study coordinator.

Study Location(s):

Seattle Children's Main Hospital Campus

Principal Investigator:

Dr. Sarah Leary