Current Research Studies

COVID-19 - Pfizer Bivalent Vaccine Study

Condition or Therapy:




What is the goal of this study?

Researchers at Seattle Children's are doing a bivalent COVID-19 vaccine research study for children. The bivalent vaccine aims to protect against the original COVID-19 strain along with the Omicron variant.

Who can join the study?

This study might be a good fit for your child if they:

  • Group 1: Have had no prior COVID-19 vaccine and are between ≥6 months and < 2 years old


Group 2: Have received 2 or 3 doses of COVID-19 vaccine and are between ≥6 months and < 12 years old

  • Are willing to do study activities including:
    • Shots
    • Blood draws
    • Nasal swab(s)
    • Visits at Seattle Children’s Hospital
  • Are healthy or medically stable
  • Have a parent who can communicate with study staff by phone

What will happen if my child takes part in this study?

Participants who join the study would:

  • Receive either four doses (group 1) OR one to two doses (group 2) of a bivalent COVID-19 vaccine during the study depending on group and age
  • Have blood drawn to measure antibodies (“germ fighters”)
  • Record reactions after the shots and tell the study team
  • Report any illnesses with COVID-like symptoms

Who can I contact for more information?

Contact for more information.  

Study Location(s):

Seattle Children's Research Institute

Principal Investigator:

Dr. Janet A. Englund, MD