Current Research Studies

Cancer – CONNECT 1701: Phase 1 Study of Ribociclib and Everolimus Following Radiation Therapy in Children with Newly Diagnosed Non-Biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)

Condition or Therapy:

Diffuse intrinsic pontine glioma, glioblastoma, anaplastic astrocytoma


Cancer and Blood Disorders

What is the goal of this study?

The goal of this study is to learn about how the combination of Ribociclib and Everolimus work when give to patients after radiation therapy.

Who can join the study?

This study may be a good fit for children and young adults who:

  • are between 12 months and 30 years old, and
  • have been diagnosed with diffuse intrinsic pontine glioma (DIPG)

What will happen if my child takes part in this study?

You can read more about this study on

Who can I contact for more information?

To learn more, call 206-987-2106 or email the study coordinator.

Study Location(s):

Seattle Children's Main Hospital Campus

Principal Investigator:

Dr. Sarah Leary