Current Research Studies

LOGIC

LOGIC

What is the goal of the study?

This is a multi-center longitudinal observational study of four ChiLDReN cholestatic liver diseases, (ALGS, PFIC, Alpha-1 antitrypsin, BRIC),utilizing collection of diagnostic, clinical, and outcome data at defined intervals for up to 20 years. These data will be used to test hypotheses related to these diseases as a group and to specific diseases. The development of the serum, urine and tissue repository, and the maintenance of a DNA bank for genetic analyses, will be an invaluable resource for current and future ancillary investigations into the pathogenesis, genetics, and progression of cholestatic liver injury in the infant and child, and the identification of modifier genes and biomarkers predictive of outcomes.

Who can participate in the study?

Please contact the study team listed below to learn more.

Study Team: