Current Research Studies

Cancer – AEWS1031: Phase 3 Randomized Trial of Adding Vincristine-topotecan-cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-metastatic Ewing Sarcoma

Condition or Therapy:

Ewing sarcoma, primitive neuroetodermal tumor (PNET)


Cancer and Blood Disorders
Study Number: AEWS1031

What is the goal of this study?

This study compares treatment of chemotherapy and the combination of chemotherapy with topotecan hydrochloride in patients with extracranial Ewing sarcoma.

Who can join the study?

This study may be a good fit for children and young adults who:

  • are up to 50 years old and
  • are newly diagnosed with non-metastatic Ewing sarcoma or primitive neuroetodermal tumor (PNET).

What will happen if my child takes part in this study?

You can read more about this study on

Who can I contact for more information?

To learn more, call 206-987-2106 or email the study coordinator.

Study Location(s):

Seattle Children's Main Hospital Campus

Principal Investigator:

Dr. Douglas Hawkins