Current Research Studies

Cancer – ADVL1217: Phase 1 Study of MK-1775 Concurrent with Local Radiation Therapy for the Treatment of Newly Diagnosed Children with Diffuse Intrinsic Pontine Gliomas

Condition or Therapy:

Diffuse intrinsic pontine gliomas (DIPG)


Cancer and Blood Disorders

What is the goal of this study?

This phase 1 trial studies the side effects and best dose of adavosertib when given together with local radiation therapy in treating children with newly diagnosed diffuse intrinsic pontine gliomas (DIPG). 

Who can join the study?

This study might be a good fit for children and young adults who:

  • Are between 37 month and 21 years old
  • Have been newly diagnosed with diffuse intrinsic pontine gliomas (DIPG)

What will happen if my child takes part in this study?

You can read more about this study on

Who can I contact for more information?

To learn more, call 206-987-2106 or send us an email.

Study Location(s):

Seattle Children's Main Hospital Campus

Principal Investigator:

Dr. Julie Park