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Center for Clinical and Translational Research

CCTR Leadership


Center Director

Bonnie Ramsey, MD

Bonnie Ramsey CCTR leadership

Professor of Pediatrics, Pulmonary
Director, Center for Clinical and Translational Research (CCTR)
Director, Cystic Fibrosis Therapeutics Development Network (CFTDN) Coordinating Center

Dr. Bonnie W. Ramsey is the director of the CCTR at Seattle Children’s Research Institute and co–principal investigator of the Institute for Translational Health Sciences, which provides extensive clinical research infrastructure at Seattle Children’s. She is a professor and vice chair for research in the Department of Pediatrics and holds the Endowed Chair in Cystic Fibrosis at the University of Washington School of Medicine.

Ramsey is an attending physician at Seattle Children’s Hospital and the associate director of the cystic fibrosis (CF) clinic. Her career has focused on clinical care and research in the field of CF. For the past 13 years, Ramsey has directed the Coordinating Center for the CFTDN, a 77-center national clinical trials network that has successfully conducted more than 60 therapeutic trials assisting in the development of novel treatments for patients with this disorder. Ramsey is internationally recognized for her work in developing new therapies for patients with CF.

Executive Faculty Leadership Team

Doug Hawkins, MD


Professor of Pediatrics and Associate Division Chief, Hematology/Oncology
Associate Director, CCTR

Dr. Doug Hawkins is an associate director of the CCTR and associate division chief for Hematology/Oncology, and oversees the CCTR Faculty Research Support Fund program. He has devoted his career to the refinement of treatment and the application of novel therapies for pediatric sarcomas, including rhabdomyosarcoma (RMS), Ewing sarcoma and osteosarcoma. Hawkins is the institutional Children’s Oncology Group (COG) principal investigator and is the national chair of the Soft Tissue Sarcoma Committee, where he oversees the strategic planning, conduct and analysis of RMS and other soft tissue sarcomas within the COG.

Margaret Rosenfeld, MD, MPH


Associate Professor of Pediatrics, Pulmonary
Associate Director, CCTR

Dr. Margaret Rosenfeld is an associate director of the CCTR, co-director of the Seattle Children’s Fellows College and medical director of the Pulmonary Function Laboratory. She also oversees the newly implemented CCTR Clinical Research Scholars Program. Rosenfeld’s clinical interests focus on the diagnosis and management of respiratory illnesses in children of all ages. Her research focuses on the assessment and treatment of early cystic fibrosis (CF) lung disease, including infant and preschool lung function tests; determining risk factors for early acquisition of Pseudomonas aeruginosa; and clinical trials in infants with CF. She is also an investigator in a national network investigating rare disorders of mucociliary clearance, including primary ciliary dyskinesia.

Nicole Mayer-Hamblett, PhD

Nicole Mayer-Hamblett

Research Associate Professor of Pediatrics, Pulmonary
Director, Children’s Core for Biomedical Statistics (CCBS)
Co-Director, Cystic Fibrosis Therapeutics Development Network (CFTDN)

Dr. Nicole Mayer-Hamblett is the director of the Children’s Core for Biomedical Statistics (CCBS) and a co-director of the CFTDN. Her research interests include developing novel longitudinal analysis methodology and maximizing the efficiency of using repeated measures in randomized clinical trials. Hamblett provides statistical training to clinical researchers and scientists through guest lectures and short courses, with applications to both the preclinical and clinical fields. As director of the CCBS, Hamblett oversees the statistical consultation to several pediatrics faculty members throughout Children’s and uses her expertise in the conduct and analysis of pediatric studies to collaborate in the development of both local and NIH grant submissions.

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