Debley Lab

Selected Publications

  1. Reeves SR, Kang I, Chan CK, Barrow KA, Kolstad TK, White MP, Ziegler SF, Wight TN, Debley JS. Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts. Respir Res. 2018 Aug 2;19(1):146. doi: 10.1186/s12931-018-0849-1.
  2. Reeves SR, Barrow KA, White MP, Rich LM, Naushab M, Debley JS. Stability of gene expression by primary bronchial epithelial cells over increasing passage number. BMC Pulm Med. 2018 May 29;18(1):91. doi: 10.1186/s12890-018-0652-2.
  3. James RG, Reeves SR, Barrow KA, White MP, Glukhova VA, Haghighi C, Seyoum D, Debley JS. Deficient Follistatin-like 3 Secretion by Asthmatic Airway Epithelium Impairs Fibroblast Regulation and Fibroblast-to-Myofibroblast Transition. Am J Respir Cell Mol Biol. 2018.
  4. Altman MC, Reeves SR, Parker AR, Whalen E, Misura KM, Barrow KA, James RG, Hallstrand TS, Ziegler SF, Debley JS. Interferon response to respiratory syncytial virus by bronchial epithelium from children with asthma is inversely correlated with pulmonary function. J Allergy Clin Immunol. 2018 Aug;142(2):451-459. doi: 10.1016/j.jaci.2017.10.004. Epub 2017 Oct 26
  5. Reeves SR, Kaber G, Sheih A, Aronica MA, Merriless MJ, Debley JS, Frevert CW, Ziegler SF, Wight TN. Subepithelial Accumulation of Versican in a Cockroach Antigen-Induced Murine Model of Allergic Asthma. J Histochem Cytochem. 2016;64(6):364-80.
  6. Ulm A, Mayhew CN, Debley JS, Khurana Hershey GK, Ji H. Cultivate primary nasal epithelial cells from children and reprogram into induced pluripotent stem cells. J Vis Exp. 2016;(109).
  7. Reeves SR, Kolstad T, Lien TY, Herrington-Shaner SN, Debley JS. Fibroblast-Myofibroblast Transition is Differentially Regulated by Bronchial Epithelial Cells from Asthmatic Children. Respiratory Research, 2015;16(1):21.
  8. Reeves SR, Kolstad T, Lien TY, Elliott M, Ziegler SF, Wight TN, Debley JS. Asthmatic Airway Epithelial Cells Differentially Regulate Fibroblast Expression of Extracellular Marix Components. J Allergy Clin Immunol, 2014; 134(3):663-70.
  9. Elliott M, Heltshe SL, Stamey DC, Cochrane ES, Redding GJ, Debley JS. Exhaled Nitric Oxide Predicts Persistence of Wheezing, Exacerbations, and Decline in Lung Function in Wheezy Infants and Toddlers. Clinical and Experimental Allergy. 2013;43(12):1351-6.
  10. Iwanaga K, Elliott MS, Vedal S, Debley JS. Urban Particulate Matter Induces Pro-Remodeling Factors by Airway Epithelial Cells from Healthy and Asthmatic Children. Inhalation Toxicology. 2013;25(12):653-60.
  11. Miazgowicz MM, Elliott MS, Debley JS, Ziegler SF. Respiratory Syncytial Virus Induces Functional Thymic Stromal Lymphopoietin Receptor in Airway Epithelial Cells. J Inflamm Res. 2013;6:53-61.
  12. Lee HC, Headley MB, Loo Y, Berlin A, Gale M, Debley JS, Lukacs NW, Ziegler SF. Thymic Stromal Lymphopoietin is induced by Respiratory Syncytial Virus-infected Airway Epithelial Cells and Promotes a Type 2 Response to Infection. J Allergy Clin Immunol. 2012 Nov;130(5):1187-1196.
  13. Debley JS, Cochrane ES, Redding GJ, Carter ER. Lung Function and Biomarkers of Airway Inflammation During and After Hospitalization for Acute Exacerbations of Childhood Asthma Associated with Viral Respiratory Symptoms. Asthma Ann Allergy Asthma Immunol. 2012 Aug;109(2):114-20.
  14. Lopez-Guisa JM, Powers C, File D, Cochrane E, Jimenez N, Debley JS. Airway Epithelial Cells from Asthmatic Children Differentially Express Proremodeling Factors. J Allergy Clin Immunol 2012;129(4):990-7.
  15. Debley J, Stanojevic S, Filbrun AG, Subbarao P. Bronchodilator Responsiveness in Wheezy Infants and Toddlers is not associated with Asthma Risk Factors. Pediatric Pulmonology 2012;47(5):421-8.
  16. Debley JS, Ohanian AS, Spiekerman CF, Aitken ML, Hallstrand TS. Effects of bronchoconstriction, minute ventilation, and deep inspiration on the composition of exhaled breath condensate (EBC). Chest 2011 Jan;139(1):16-22.
  17. Debley JS, Stamey DC, Cochrane ES, Gamma KL, Redding GJ. Exhaled Nitric Oxide, Lung Function, and Exacerbations in Wheezy Infants and Toddlers. J Allergy Clin Immunol. 2010 Jun;125(6):1228-1234.
  18. Debley JS, Hallstrand TS, Monge T, Ohanian A, Redding G, Zimmerman J. Methods to Improve Measurement of Cysteinyl Leukotrienes in Exhaled Breath Condensate from Subjects with Asthma and Healthy Controls. J Allergy Clin Immunol 2007;120(5):1216-7.
  19. Hallstrand, TS, Debley JS, Farin FM, Henderson WR Jr. Role of MUC5AC in the Pathogenesis of Exercise-Induced Bronchoconstriction. J Allergy Clin Immunol 2007;119(5):1092-8.
  20. Debley JS, Carter ER, Redding, GJ. Prevalence and Impact of Gastroesophageal Reflux in Adolescents with Asthma: A Population-Based Study. Pediatr Pulmonol 2006 May; 41(5):475-81.
  21. Debley JS, Carter ER, Rosenfeld M, Gibson R, Redding GJ. The Prevalence of Ibuprofen-Sensitive Asthma in Children: A Randomized Controlled Bronchoprovocation Challenge Study. J Pediatrics 2005 August;147(2): 233-38.
  22. Carter ER, Debley JS, Redding, GJ. Changes in Asthma Prevalence and Impact on Health and Function in Seattle Middle-School Children: 1995 vs 2003. Ann Allergy Asthma Immunol; 2005 Jun;94(6):634-9.
  23. Debley JS, Smith JM, Redding GJ, Critchlow CW. Childhood Asthma Hospitalization Risk After Cesarean Delivery in Former Term and Premature Infants. Ann Allergy Asthma Immunol 2005 Feb;94(2):228-33.
  24. Debley JS, Redding GJ, Critchlow CW. Impact of Adolescence and Gender on Asthma Hospitalization: A Population-Based Birth Cohort Study. Pediatr Pulmonol 2004 Dec;38(6):443-50.