Parsons Lab

Selected Publications

Listed below is a selection of recent publications from the Parsons Lab.

See full list on PubMed

Toxoplasma calcium-dependent protein kinase 1 inhibitors: probing activity and resistance using cellular thermal shift assaysAntimicrob Agents Chemother. Scheele S, Geiger JA, DeRocher AE, … Parsons M.  2018 May 25;62(6). pii: e00051-18. 

Two essential Thioredoxins mediate apicoplast biogenesis, protein import, and gene expression in Toxoplasma gondiiBiddau M, Bouchut A, Major J, … Parsons M, Sheiner L. PLoS Pathog. 2018 Feb 22;14(2):e1006836. 

Extended-spectrum antiprotozoal bumped kinase inhibitors: A reviewVan Voorhis WC, Doggett JS, Parsons M, et al. Exp Parasitol. 2017 Sep;180:71-83.  

NADH dehydrogenase of Trypanosoma brucei is important for efficient acetate production in bloodstream formsSurve SV, Jensen BC, Heestand M, Mazet M, Smith TK, Bringaud F, Parsons M, Schnaufer A. Mol Biochem Parasitol. 2017 Jan;211:57-61 

Advancing Trypanosoma brucei genome annotation through ribosome profiling and spliced leader mappingParsons M, Ramasamy G, Vasconcelos EJ, Jensen BC, Myler PJ. Mol Biochem Parasitol. 2015 Aug;202(2):1-10.

SAR studies of 5-aminopyrazole-4-carboxamide analogues as potent and selective inhibitors of Toxoplasma gondii CDPK1Huang W, Ojo KK, Zhang Z, … Parsons M, et al. ACS Med Chem Lett. 2015 Oct 22;6(12):1184-1189.

A novel protein kinase is essential in bloodstream Trypanosoma bruceiJensen BC, Booster N, Vidadala RS, Maly DJ, Parsons M. Int J Parasitol. 2016 Jul;46(8):479-83.  

Illuminating parasite protein production by ribosome profilingParsons M, Myler PJ. Trends Parasitol. 2016 Jun;32(6):446-457.

Vesicles bearing Toxoplasma apicoplast membrane proteins persist following loss of the relict plastid or Golgi body disruptionBouchut A, Geiger JA, DeRocher AE, Parsons M. PloS One. 2014; 9(11):e112096.

Extensive stage-regulation of translation revealed by ribosome profiling of Trypanosoma bruceiJensen BC, Ramasamy G, Vasconcelos EJ, Ingolia NT, Myler PJ, Parsons M. BMC Genomics. 2014 Oct 20;15:911