Listed below is a selection of recent publications from the Myler Lab. See a list of Dr. Myler’s publications on PubMed.

Structural insight into how bacteria prevent interference between multiple divergent type IV secretion systemsGillespie JJ, Phan IQ, Scheib H, Subramanian S, Edwards TE, Lehman SS, Piitulainen H, Rahman MS, Rennoll-Bankert KE, Staker BL, Taira S, Stacy R, Myler PJ, Azad AF, Pulliainen AT. MBio.2015 Dec 8;6(6):e01867-15

High-resolution crystal structure of dimeric VP40 from Sudan ebolavirusClifton MC, Bruhn JF, Atkins K … Myler PJ, Saphire EO. J Infect Dis. 2015 Oct 1;212 Suppl 2:S167-71. 

Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world Leishmania providing evidence for conserved exosomal RNA packagingLambertz U, Oviedo Ovando ME, Vasconcelos EJ, Unrau PJ, Myler PJ, Reiner NE. BMC Genomics. 2015 Mar 5;16:151

Increasing the structural coverage of tuberculosis drug targets. Baugh L, Phan I, Begley DW … Stacy R, Stewart LJ, Edwards TE, Van Voorhis WC, Myler PJ. Tuberculosis (Edinb). 2015 Mar;95(2):142-8.  

Defining the sequence requirements for the positioning of base J in DNA using SMRT sequencing. Genest PA, Baugh L, Taipale A … Myler PJ, Borst P.  Nucleic Acids Res. 2015 Feb 27;43(4):2102-15  

Extensive stage-regulation of translation revealed by ribosome profiling of Trypanosoma bruceiJensen BC, Ramasamy G, Vasconcelos EJ, Ingolia NT, Myler PJ, Parsons M. BMC Genomics. 2014 Oct 20;15:911.

Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1Moen SO, Abendroth J, Fairman JW, … Phan I, Staker BL, Stacy R, Myler PJ, Lorimer D, Edwards TE. Sci Rep. 2014 Aug 4;4:5944. 

Genetic analysis of Leishmania donovani tropism using a naturally attenuated cutaneous strainZhang WW, Ramasamy G, McCall LI, … Myler P, Matlashewski G. PLoS Pathog. 2014 Jul 3;10(7):e1004244.

Regulation dynamics of Leishmania differentiation: deconvoluting signals and identifying phosphorylation trendsTsigankov P, Gherardini PF, Helmer-Citterich M, Späth GF, Myler PJ, Zilberstein D. Mol Cell Proteomics. 2014 Jul;13(7):1787-99. 

A structural biology approach enables the development of antimicrobials targeting bacterial immunophilinsBegley DW, Fox D 3rd, Jenner D, … Stacy R, Myler PJ, Staker BL, et al.  Antimicrob Agents Chemother. 2014;58(3):1458-67.