The Ben Towne Center's labs are at the forefront of developing therapies that use the immune system to destroy cancer, without the devastating side effects of chemotherapy or radiation.
The Crane Lab unravels exactly how cancer cells disarm immune cells, with the goal of finding ways to reprogram those immune cells so they can elude cancer's defenses and destroy brain tumors, neuroblastoma and other cancers.
The Jensen Lab investigates ways to reprogram immune cells by inserting new genetic instructions that tell them to find cancer cells and destroy them. The lab carries its innovations into clinical trials, and uses the information learned there to make immunotherapies safer and more powerful.
The Kalia Lab is enabling progress toward immunotherapies that can be applied to any type of cancer.
The Orentas Lab investigates how the immune system and CAR T-cell immunotherapies can be leveraged to fight childhood childhood cancers like rhabdomyosarcoma, osteosarcoma, Ewing’s sarcoma and neuroblastoma.
The Sarkar Lab is finding ways to help the immune system remember cancer and attack it if it relapses – whether that’s months or decades after a child goes into remission.