As one of the nation's top five pediatric research centers, Seattle Children's Research Institute is dedicated to providing hope, care and cures to help every child live the healthiest and most fulfilling life possible.

A History of Groundbreaking Discoveries

Research InstituteOur investigators are involved in hundreds of projects that cover every phase of research, from studying how diseases work to improving investigational therapies. They have pioneered groundbreaking cystic fibrosis treatments and cutting-edge cancer therapies that help a child's immune system defeat cancer, and made other major contributions to pediatric medicine. 

Now, with 607,000 square feet of clinical, laboratory and office space, a workforce of over 1,600 people and over $102 million in total extramural funding for the 2016 fiscal year, we are working toward the next wave of lifesaving discoveries. To accelerate our progress, the research institute is organized into seven centers, each one specializing in areas like cancer immunotherapy, neuroscience and child health and behavior. The centers are supported by the Office of Science-Industry Partnerships and faculty from the Treuman Katz Center for Pediatric Bioethics, the nation's first pediatric bioethics center.

Planning for a Bright Future

We are using the principles of continuous performance improvement (CPI) to reduce the administrative burden of our research teams so they can expedite their work to develop lifesaving cures, accelerate clinical research and address issues affecting the health of children and families around the world. Dr. Jim Hendricks, president of Seattle Children’s Research Institute, discusses this work in a video.

Building Cure imageSeattle Children’s Research Institute is currently working on the development of Building Cure, a 540,000 square foot research building, which will be dedicated to developing therapies for children with diseases such as cancer, type 1 diabetes and sickle cell anemia. Building Cure will include features such as research labs, a Science Discovery Lab for students and the community to learn about science, as well as the “Cure Factory”, a state-of-the-art manufacturing facility that will expand our ability to translates laboratory discoveries into cell therapies for patients using immunotherapy and gene therapy. Learn more about Building Cure and the progress of the expansion.

Collaborating With World-Renowned Partners

Researchers in the centers work in close collaboration with one another, their colleagues at partner institutions including the University of Washington and Fred Hutch and our healthcare providers at Seattle Children's Hospital, one of U.S. News & World Report's top five children's hospitals. This collaboration is one of our key strengths, allowing our faculty to draw on a variety of disciplines and techniques as they pursue solutions to some of medicine's most complex problems.

Turning Discoveries Into Lifesaving Therapies

Research Graph 2017_b We understand that finding a potential cure in a lab isn't enough. We are dedicated to recruiting and retaining talented researchers – and creating the facilities and programs they need to transform important findings into viable, real-world therapies. 

Our key infrastructure includes flow cytometry labs, a 5,000-square-foot pediatric clinical research center and a multimillion-dollar cell processing facility that places us among the few pediatric facilities that meet strict FDA requirements for manufacturing therapies.

Research Centers

Ben Towne Center for Childhood Cancer Research

Director: Michael Jensen, MD

Researchers develop innovative treatments that maximize the well-being of children with cancer and the quality of life for survivors of childhood cancer. Learn more.

Center for Child Health, Behavior and Development

Director: Dimitri A. Christakis, MD, MPH

Researchers work collaboratively to address obesity, adolescent depression, the impact of media and other major issues affecting children. Learn more.

Center for Clinical and Translational Research

Director: Bonnie W. Ramsey, MD

Clinical and translational research takes discoveries made in the laboratory and translates them into therapies that doctors and patients can use in daily life. Learn more.

Center for Developmental Biology and Regenerative Medicine

Director: David Beier, MD, PhD

Researchers work to restore children's health after injury through repair, regeneration or replacement of tissues, cells and organs. Learn more.

Center for Global Infectious Disease Research

Co-Directors: Lisa M. Frenkel, MD, and Timothy M. Rose, PhD

Researchers work to understand, prevent and treat infectious disease affecting people across the globe from neonatal to adult stages of life. Learn more.

Center for Immunity and Immunotherapies

Director: David J. Rawlings, MD

Through scientific discovery and innovation, researchers work to harness the power of the immune system to prevent, treat or cure life-threatening childhood diseases. Learn more.

Center for Integrative Brain Research

Director: Jan (Nino) Ramirez, PhD

Researchers are developing new ways to prevent, treat and potentially cure pediatric neurological disorders. Learn more.

Center for Pediatric Nursing Research 

Director: Debra Ridling, PhD

Designed specifically for nurses, this center advances clinical practice focused research among Seattle Children’s nurses at all career levels. Learn more.