Simon P. Horslen, MB ChB

Simon P. Horslen, MB ChB

Gastroenterology, Hepatology, Transplantation, Gastroenterology and Hepatology Research, Intestinal Rehabilitation

On staff since May 2005

Children's Title: Medical Director, Solid Organ Transplantation

Academic Title: Professor

Research Center: Center for Clinical and Translational Research

"With continuous innovations in allocation policy, donor awareness, organ preservation, surgical technique and medical care, we now fully expect all the infants and children that we list for liver transplantation to get to transplant and to recover rapidly from the operation, and to grow up to adulthood and have families of their own. The fact that this does not happen in 100% of patients even though we are getting closer every year drives me onward. The honor of caring for the children who have driven the growth of the medical specialty of liver transplantation, from its infancy to its current sophistication, continues to excite and inspire me."

  • Simon Horslen, MB ChB, is Director of the Hepatobiliary and Intestinal Failure programs and Medical Director for Solid Organ Transplantation at Seattle Childrens Hospital as well as Professor of Pediatrics at the University of Washington School of Medicine. Horslen earned his medical degree from the University of Bristol, England.

    He is a founding fellow of the Royal College of Pediatric and Child Health (UK) and is accredited in general pediatrics and pediatric gastroenterology. His clinical and research interests include metabolic liver disease, acute liver failure, intestinal failure, and liver and intestine transplant. He is past-chairman of the UNOS Pediatric Transplant Committee and of the Pediatric Community of Practice of the American Society of Transplantation. He is current Chair of SPLIT (Studies in Pediatric Liver Transplantation) Council, Council member for the Intestine Transplantation Association (ITA). He is the site Principle Investigator for pediatric multicenter studies in liver transplantation (SPLIT), acute liver failure (PALF). Additionally, he is a co-investigator in a large NIH funded consortium (ChiLDReN) researching many aspects of liver disease in children.

    • Lindsey Puyallup, WA 11.20.12

      Dr. Horslen has been involved with our son's Biliary Atresia since birth. He has always been encouraging to me as his parent, always telling me that my insight to my son has always been constructive, crucial and effectual in his care. This ment so much to me as Caleb's health had been declining to a life threatening state for over a year. What I appritiate about Dr. Horslen the most is that he always encouraged me to study and know my son's conditions, labs, procedures, etc. He was and is always willing to teach me as much as I would like to know. This ability to connect with me as a parent on a heart to heart level, discerning not only my son but myself as well has given me great comfort in times of great emotion. My son recieved his liver transplant at the age of 15 mos. I would and will continue to recomend Dr. Simon Horslen to anyone who is in need of his services.

    • Ross Lincoln, NE 04.21.12

      When I was fourteen, I developed autoimmune hepatitis. My family doctor was unable to successfully diagnose my condition. Eventually I was recommended to see a specialist, who ending up being Dr. Horslen. Within minutes of meeting, Dr. Horslen made the correct diagnosis, which was confirmed by the biopsy. He immediately began treating me. Due to Dr. Horslen's insight, my liver was saved before it was too late. I am now 22, and my autoimmune hepatitis has been in remission for years thanks in part to Dr. Horslen's guidance. Not only did Dr. Horslen make the correct diagnosis, allowing for me to live this past decade relatively healthy, but he did so with great care. He was never forceful, respected my opinions, and was always realistic and honest. I am very grateful to have been under the care of Dr. Horslen. Any family would be lucky to have him treat their child.

    • Paulette Bahamas 03.13.12

      Dr. Horslen took care of my son Freddie Dean. My son is now living a normal life in the Bahamas . Thanks to Dr. Horslen and his caring team. I highly recommend Dr. Horslen to any child suffering from a GI or liver disease.

    • Andy Joint Base Lewis - McChord, WA 12.27.10

      With Dr. Horslen, we feel very trustworthy with him addressing our son's medical issues especially when it involves the bowel and liver. He is one of the best doctors that we feel that can provide the expertise our son needs concerning his medical condition. Andrew

  • Award Name Award Description Awarded By Award Date
    SEATTLE MAGAZINE TOP DOCTOR - 2016 Seattle Magazine 2016
    Seattles Top Doctor 2016 Seattle Met Magazine 2016
    SEATTLE'S TOP DOCTOR - 2015 Seattle Met Magazine 2015
    U.S. News Top Doctor U.S. News and World Report 2012
    Seattle Magazine Top Doctor - 2012 Seattle Magazine Top Doctor - 2012 Seattle Magazine 2012
  • Presentations Title Event Location Date
    Infantile Liver Disease: Diagnosis, Management & Transplantation Unknown Anchorage, Alaska Nov. 17, 2009
    Intestinal failure and transplantation at Seattle Childrens Hospital XIth International Small Bowel Transplant Symposium Bologna, Italy Sept. 9, 2009
  • Grant Title Grantor Amount Award Date
    Childhood Liver Disease Research and Education Network Clinical Center in SeattleRole NIH/NIDDK July 1, 2009
    Pilot study of the safety and immunogenicity of a rotavirus vaccine in infants at risk for intestinal failure Thrasher Research Fund May 14, 2009
    Intestinal failure in children: A contemporary retrospective review by the Pediatric Intestinal Failure Consortium NIH April 1, 2008
    A Multi-Center Group to Study Acute Liver Failure in Children NIH/NIDDK Sept. 15, 2005
    Studies in Pediatric Liver Transplantation NIH May 6, 2005


Board Certification(s)

Pediatric Gastroenterology (Non-ABMS)
General Pediatrics (Non-ABMS)

Medical/Professional School

University of Bristol, Bristol, UK


Pediatrics, Westminster's Children's Hospital, London
Pediatrics, King's College Hospital NHS Trust, London
Pediatrics, Peterborough District Hospital, Cambridgeshire
Leicester Royal Infirmary, Liecester
Pediatrics, Torbay Hospital, Torquay


Pediatrics, Hospital For Sick Children, London
Pediatrics, King's College Hospital NHS Trust, London
Pediatrics, Royal Children's Hospital, Melbourne
Pediatrics, King's College Hospital NHS Trust, London
Sheffield University, Sheffield
Sheffield University, Sheffield
Birmingham Children's Hospital, Birmingham

Clinical Interests

Pediatric Hepatology, liver based metabolic disease, acute liver failure, intestinal failure, liver transplantation, intestine transplantation

Research Focus Area

Translational Research