Rusty Novotny, MD

Rusty Novotny, MD

Neurosciences Center, Neurology, Epilepsy Program

On staff since July 2009

Children's Title: Director, Epilepsy

Academic Title: Professor, Neurology and Pediatrics

Foundation Title: Alvord, Gerlich and Rhodes Family Endowed Chair in Pediatric Epilepsy

Research Center: Center for Integrative Brain Research

"I was first attracted to neuroscience as an undergraduate and have been fascinated ever since. I love communicating with patients and families to help them understand the complexities and wonders of the brain. I am also amazed by my colleagues both within my program and throughout the hospital. My focus is on identifying new tools that allow us to safely investigate the brain these tools have been essential to our understanding of neurological disorders in children and help us provide better treatments. I am profoundly grateful to be a pediatric specialist at Seattle Children's."

  • Patient Testimonials

  • Awards and Honors

    Award Name Award Description Awarded By Award Date
    SEATTLE TOP DOCTOR - 2022 Seattle Magazine 2022
    Seattle Top Doctor - 2019 Seattle Magazine 2019
    SEATTLE'S TOP DOCTOR - 2018 Seattle Magazine 2018
    SEATTLE'S TOP DOCTOR - 2017 Seattle Magazine 2017
    Fellow American Epilepsy Society Dec. 2016
    SEATTLE MAGAZINE TOP DOCTOR - 2016 Seattle Magazine 2016
    Seattles Top Doctor 2016 Seattle Met Magazine 2016
    SEATTLE MAGAZINE TOP DOCTOR - 2015 Seattle Magazine 2015
    Fellow American Academy of Neurology May 2014
    Seattle Magazine Top Doctor - 2012 Seattle Magazine Top Doctor - 2012 Seattle Magazine 2012
    U.S. News Top Doctor U.S. News and World Report 2012
     Ad-Hoc reviewer NIH Study section - NIDA NIDA Jan 1, 2009
    S. Weir Mitchell Award Award to Best Manuscript from Junior Investigator American Academy of Neurology 1985
  • Publications

    Other Publications

    • Grassia F, Poliakov AV, Poliachik SL, Casimo K, Friedman SD, Shurtleff H, Giussani C, Novotny EJ Jr, Ojemann JG, Hauptman JS
      Changes in resting-state connectivity in pediatric temporal lobe epilepsy.
      29932365 Journal of neurosurgery. Pediatrics, 2018 Jun 22 : 1-6
    • Casimo K, Grassia F, Poliachik SL, Novotny E, Poliakov A, Ojemann JG
      Preservation of electrophysiological functional connectivity after partial corpus callosotomy: case report.
      29775133 Journal of neurosurgery. Pediatrics, 2018 May 18 : 1-6
    • Sánchez Fernández I, Gaínza-Lein M, Abend NS, Anderson AE, Arya R, Brenton JN, Carpenter JL, Chapman KE, Clark J, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Helseth AR, Jackson MC, Kapur K, Lai YC, McDonough TL, Mikati MA, Nayak A, Peariso K, Riviello JJ Jr, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright MS, Wilfong A, Williams K, Loddenkemper T, Pediatric Status Epilepticus Research Group (pSERG).
      Factors associated with treatment delays in pediatric refractory convulsive status epilepticus.
      29643084 Neurology, 2018 May 8 : 90(19)e1692-e1701 PMCID:PMC5952974
    • Grinspan ZM, Shellhaas RA, Coryell J, Sullivan JE, Wirrell EC, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Millichap J, Berg AT
      Comparative Effectiveness of Levetiracetam vs Phenobarbital for Infantile Epilepsy.
      29435578 JAMA pediatrics, 2018 Apr 1 : 172(4)352-360 PMCID:PMC5875334
    • Weaver KE, Poliakov A, Novotny EJ, Olson JD, Grabowski TJ, Ojemann JG
      Electrocorticography and the early maturation of high-frequency suppression within the default mode network.
      29192865 Journal of neurosurgery. Pediatrics, 2018 Feb. : 21(2)133-140
    • Wang AC, Ibrahim GM, Poliakov AV, Wang PI, Fallah A, Mathern GW, Buckley RT, Collins K, Weil AG, Shurtleff HA, Warner MH, Perez FA, Shaw DW, Wright JN, Saneto RP, Novotny EJ, Lee A, Browd SR, Ojemann JG
      Corticospinal tract atrophy and motor fMRI predict motor preservation after functional cerebral hemispherectomy.
      29099351 Journal of neurosurgery. Pediatrics, 2018 Jan. : 21(1)81-89
    • Shinnar RC, Shinnar S, Cnaan A, Clark P, Dlugos D, Hirtz DG, Hu F, Liu C, Masur D, Weiss EF, Glauser TA, Childhood Absence Epilepsy Study Group.
      Pretreatment behavior and subsequent medication effects in childhood absence epilepsy.
      28916534 Neurology, 2017 Oct 17 : 89(16)1698-1706 PMCID:PMC5644466
    • Berg AT, Coryell J, Saneto RP, Grinspan ZM, Alexander JJ, Kekis M, Sullivan JE, Wirrell EC, Shellhaas RA, Mytinger JR, Gaillard WD, Kossoff EH, Valencia I, Knupp KG, Wusthoff C, Keator C, Dobyns WB, Ryan N, Loddenkemper T, Chu CJ, Novotny EJ Jr, Koh S
      Early-Life Epilepsies and the Emerging Role of Genetic Testing.
      28759667 JAMA pediatrics, 2017 Sep 1 : 171(9)863-871 PMCID:PMC5710404
    • Novotny EJ Jr
      Early genetic testing for neonatal epilepsy: When, why, and how?
      28733342 Neurology, 2017 Aug 29 : 89(9)880-881
    • Epi4K Consortium., EuroEPINOMICS-RES Consortium., Epilepsy Phenome Genome Project.
      Application of rare variant transmission disequilibrium tests to epileptic encephalopathy trio sequence data.
      28513609 European journal of human genetics : EJHG, 2017 June : 25(7)894-899 PMCID:PMC5520073
    • Epi4K consortium., Epilepsy Phenome/Genome Project.
      Ultra-rare genetic variation in common epilepsies: a case-control sequencing study.
      28102150 The Lancet. Neurology, 2017 Feb. : 16(2)135-143
    • Cnaan A, Shinnar S, Arya R, Adamson PC, Clark PO, Dlugos D, Hirtz DG, Masur D, Glauser TA, Childhood Absence Epilepsy Study Group.
      Second monotherapy in childhood absence epilepsy.
      27986874 Neurology, 2017 Jan 10 : 88(2)182-190 PMCID:PMC5224720
    • EuroEPINOMICS-RES Consortium. Electronic address: euroepinomics-RES@ua.ac.be., Epilepsy Phenome/Genome Project., Epi4K Consortium., EuroEPINOMICS-RES Consortium.
      De Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies.
      28061363 American journal of human genetics, 2017 Jan 5 : 100(1)179 PMCID:PMC5802994
    • Knupp KG, Leister E, Coryell J, Nickels KC, Ryan N, Juarez-Colunga E, Gaillard WD, Mytinger JR, Berg AT, Millichap J, Nordli DR Jr, Joshi S, Shellhaas RA, Loddenkemper T, Dlugos D, Wirrell E, Sullivan J, Hartman AL, Kossoff EH, Grinspan ZM, Hamikawa L, Pediatric Epilepsy Research Consortium.
      Response to second treatment after initial failed treatment in a multicenter prospective infantile spasms cohort.
      27615012 Epilepsia, 2016 Nov. : 57(11)1834-1842 PMCID:PMC5863234
    • Buckley RT, Wang AC, Miller JW, Novotny EJ, Ojemann JG
      Stereotactic laser ablation for hypothalamic and deep intraventricular lesions.
      27690656 Neurosurgical focus, 2016 Oct. : 41(4)E10
    • Casimo K, Darvas F, Wander J, Ko A, Grabowski TJ, Novotny E, Poliakov A, Ojemann JG, Weaver KE
      Regional Patterns of Cortical Phase Synchrony in the Resting State.
      27019319 Brain connectivity, 2016 July : 6(6)470-81 PMCID:PMC4976227
    • Mirzaa GM, Campbell CD, Solovieff N, Goold C, Jansen LA, Menon S, Timms AE, Conti V, Biag JD, Adams C, Boyle EA, Collins S, Ishak G, Poliachik S, Girisha KM, Yeung KS, Chung BHY, Rahikkala E, Gunter SA, McDaniel SS, Macmurdo CF, Bernstein JA, Martin B, Leary R, Mahan S, Liu S, Weaver M, Doerschner M, Jhangiani S, Muzny DM, Boerwinkle E, Gibbs RA, Lupski JR, Shendure J, Saneto RP, Novotny EJ, Wilson CJ, Sellers WR, Morrissey M, Hevner RF, Ojemann JG, Guerrini R, Murphy LO, Winckler W, Dobyns WB
      Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism.
      27159400 JAMA neurology, 2016 Jul 1 : 73(7)836-845 PMCID:PMC4979321
    • Mirzaa GM, Campbell CD, Solovieff N, Goold CP, Jansen LA, Menon S, Timms AE, Conti V, Biag JD, Olds C, Boyle EA, Collins S, Ishak G, Poliachik SL, Girisha KM, Yeung KS, Chung BH, Rahikkala E, Gunter SA, McDaniel SS, Macmurdo CF, Bernstein JA, Martin B, Leary RJ, Mahan S, Liu S, Weaver M, Dorschner MO, Jhangiani S, Muzny DM, Boerwinkle E, Gibbs RA, Lupski JR, Shendure J, Saneto RP, Novotny EJ, Wilson CJ, Sellers WR, Morrissey MP, Hevner RF, Ojemann JG, Guerrini R, Murphy LO, Winckler W, Dobyns WB
      Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism.
      27159400 JAMA neurology, 2016 May 9
    • Arya R, Gillespie CW, Cnaan A, Devarajan M, Clark P, Shinnar S, Vinks AA, Mizuno K, Glauser TA, Childhood Absence Epilepsy Study Group.
      Obesity and overweight as CAE comorbidities and differential drug response modifiers.
      27029636 Neurology, 2016 Apr 26 : 86(17)1613-21 PMCID:PMC4844235
    • Olson JD, Wander JD, Johnson L, Sarma D, Weaver K, Novotny EJ, Ojemann JG, Darvas F
      Comparison of subdural and subgaleal recordings of cortical high-gamma activity in humans.
      25907415 Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2016 Jan. : 127(1)277-284 PMCID:PMC4600028
    • Shurtleff HA, Barry D, Firman T, Warner MH, Aguilar-Estrada RL, Saneto RP, Kuratani JD, Ellenbogen RG, Novotny EJ, Ojemann JG
      Impact of epilepsy surgery on development of preschool children: identification of a cohort likely to benefit from early intervention.
      26140458 Journal of neurosurgery. Pediatrics, 2015 Oct. : 16(4)383-92
    • Shurtleff HA, Barry D, Firman T, Warner MH, Aguilar-Estrada RL, Saneto RP, Kuratani JD, Ellenbogen RG, Novotny EJ, Ojemann JG
      Impact of epilepsy surgery on development of preschool children: identification of a cohort likely to benefit from early intervention.
      26140458 Journal of neurosurgery. Pediatrics, 2015 Oct. : 16(4)383-92
    • Shinnar S, Cnaan A, Hu F, Clark P, Dlugos D, Hirtz DG, Masur D, Mizrahi EM, Moshé SL, Glauser TA, Childhood Absence Epilepsy Study Group.
      Long-term outcomes of generalized tonic-clonic seizures in a childhood absence epilepsy trial.
      26311751 Neurology, 2015 Sep 29 : 85(13)1108-14 PMCID:PMC4603882
    • Epilepsy Phenome/Genome Project Epi4K Consortium.
      Copy number variant analysis from exome data in 349 patients with epileptic encephalopathy.
      26068938 Annals of neurology, 2015 Aug. : 78(2)323-8 PMCID:PMC4646089
    • Lerche H, Novotny EJ Jr
      Microscopic brain structure revisited in genetic epilepsy.
      25740868 Neurology, 2015 Mar 31 : 84(13)1290-1
    • EuroEPINOMICS-RES Consortium., Epilepsy Phenome/Genome Project., Epi4K Consortium.
      De novo mutations in synaptic transmission genes including DNM1 cause epileptic encephalopathies.
      25262651 American journal of human genetics, 2014 Oct 2 : 95(4)360-70 PMCID:PMC4185114
    • Friedman D, Fahlstrom R, EPGP Investigators
      Racial and ethnic differences in epilepsy classification among probands in the Epilepsy Phenome/Genome Project (EPGP).
      24139856 Epilepsy research, 2013 Dec. : 107(3)306-10
    • Addis L, Chiang T, Clarke T, Hardison H, Kugler S, Mandelbaum DE, Novotny E, Wolf S, Strug LJ, Pal DK
      Evidence for linkage of migraine in Rolandic epilepsy to known 1q23 FHM2 and novel 17q22 genetic loci.
      24286483 Genes, brain, and behavior, 2013 Nov 28
    • Widdess-Walsh P, Dlugos D, Fahlstrom R, Joshi S, Shellhaas R, Boro A, Sullivan J, Geller E, EPGP Investigators.
      Lennox-Gastaut syndrome of unknown cause: phenotypic characteristics of patients in the Epilepsy Phenome/Genome Project.
      24116958 Epilepsia, 2013 Nov. : 54(11)1898-904
    • Widdess-Walsh P, Dlugos D, Fahlstrom R, Joshi S, Shellhaas R, Boro A, Sullivan J, Geller E, EPGP Investigators
      Lennox-Gastaut syndrome of unknown cause: phenotypic characteristics of patients in the Epilepsy Phenome/Genome Project.
      24116958 Epilepsia, 2013 Nov. : 54(11)1898-904
    • Epi4K Consortium., Epilepsy Phenome/Genome Project., Allen AS, Berkovic SF, Cossette P, Delanty N, Dlugos D, Eichler EE, Epstein MP, Glauser T, Goldstein DB, Han Y, Heinzen EL, Hitomi Y, Howell KB, Johnson MR, Kuzniecky R, Lowenstein DH, Lu YF, Madou MR, Marson AG, Mefford HC, Esmaeeli Nieh S, O'Brien TJ, Ottman R, Petrovski S, Poduri A, Ruzzo EK, Scheffer IE, Sherr EH, Yuskaitis CJ, Abou-Khalil B, Alldredge BK, Bautista JF, Berkovic SF, Boro A, Cascino GD, Consalvo D, Crumrine P, Devinsky O, Dlugos D, Epstein MP, Fiol M, Fountain NB, French J, Friedman D, Geller EB, Glauser T, Glynn S, Haut SR, Hayward J, Helmers SL, Joshi S, Kanner A, Kirsch HE, Knowlton RC, Kossoff EH, Kuperman R, Kuzniecky R, Lowenstein DH, McGuire SM, Motika PV, Novotny EJ, Ottman R, Paolicchi JM, Parent JM, Park K, Poduri A, Scheffer IE, Shellhaas RA, Sherr EH, Shih JJ, Singh R, Sirven J, Smith MC, Sullivan J, Lin Thio L, Venkat A, Vining EP, Von Allmen GK, Weisenberg JL, Widdess-Walsh P, Winawer MR
      De novo mutations in epileptic encephalopathies.
      23934111 Nature, 2013 Sep 12 : 501(7466)217-21 PMCID:PMC3773011
    • Epi4K Consortium, Epilepsy Phenome/Genome Project, Allen AS, Berkovic SF, Cossette P, Delanty N, Dlugos D, Eichler EE, Epstein MP, Glauser T, Goldstein DB, Han Y, Heinzen EL, Hitomi Y, Howell KB, Johnson MR, Kuzniecky R, Lowenstein DH, Lu YF, Madou MR, Marson AG, Mefford HC, Esmaeeli Nieh S, O'Brien TJ, Ottman R, Petrovski S, Poduri A, Ruzzo EK, Scheffer IE, Sherr EH, Yuskaitis CJ, Abou-Khalil B, Alldredge BK, Bautista JF, Berkovic SF, Boro A, Cascino GD, Consalvo D, Crumrine P, Devinsky O, Dlugos D, Epstein MP, Fiol M, Fountain NB, French J, Friedman D, Geller EB, Glauser T, Glynn S, Haut SR, Hayward J, Helmers SL, Joshi S, Kanner A, Kirsch HE, Knowlton RC, Kossoff EH, Kuperman R, Kuzniecky R, Lowenstein DH, McGuire SM, Motika PV, Novotny EJ, Ottman R, Paolicchi JM, Parent JM, Park K, Poduri A, Scheffer IE, Shellhaas RA, Sherr EH, Shih JJ, Singh R, Sirven J, Smith MC, Sullivan J, Lin Thio L, Venkat A, Vining EP, Von Allmen GK, Weisenberg JL, Widdess-Walsh P, Winawer MR
      De novo mutations in epileptic encephalopathies.
      23934111 Nature, 2013 Sep 12 : 501(7466)217-21 PMCID:PMC3773011
    • Shain C, Ramgopal S, Fallil Z, Parulkar I, Alongi R, Knowlton R, Poduri A, EPGP Investigators
      Polymicrogyria-associated epilepsy: a multicenter phenotypic study from the Epilepsy Phenome/Genome Project.
      23750890 Epilepsia, 2013 Aug. : 54(8)1368-75 PMCID:PMC3851304
    • Shain C, Ramgopal S, Fallil Z, Parulkar I, Alongi R, Knowlton R, Poduri A, EPGP Investigators.
      Polymicrogyria-associated epilepsy: a multicenter phenotypic study from the Epilepsy Phenome/Genome Project.
      23750890 Epilepsia, 2013 Aug. : 54(8)1368-75 PMCID:PMC3851304
    • EPGP Collaborative., Abou-Khalil B, Alldredge B, Bautista J, Berkovic S, Bluvstein J, Boro A, Cascino G, Consalvo D, Cristofaro S, Crumrine P, Devinsky O, Dlugos D, Epstein M, Fahlstrom R, Fiol M, Fountain N, Fox K, French J, Freyer Karn C, Friedman D, Geller E, Glauser T, Glynn S, Haas K, Haut S, Hayward J, Helmers S, Joshi S, Kanner A, Kirsch H, Knowlton R, Kossoff E, Kuperman R, Kuzniecky R, Lowenstein D, McGuire S, Motika P, Nesbitt G, Novotny E, Ottman R, Paolicchi J, Parent J, Park K, Poduri A, Risch N, Sadleir L, Scheffer I, Shellhaas R, Sherr E, Shih JJ, Shinnar S, Singh R, Sirven J, Smith M, Sullivan J, Thio LL, Venkat A, Vining E, von Allmen G, Weisenberg J, Widdess-Walsh P, Winawer M
      The epilepsy phenome/genome project.
      23818435 Clinical trials (London, England), 2013 Aug. : 10(4)568-86 PMCID:PMC5951634
    • EPGP Collaborative, Abou-Khalil B, Alldredge B, Bautista J, Berkovic S, Bluvstein J, Boro A, Cascino G, Consalvo D, Cristofaro S, Crumrine P, Devinsky O, Dlugos D, Epstein M, Fahlstrom R, Fiol M, Fountain N, Fox K, French J, Freyer Karn C, Friedman D, Geller E, Glauser T, Glynn S, Haut S, Hayward J, Helmers S, Joshi S, Kanner A, Kirsch H, Knowlton R, Kossoff E, Kuperman R, Kuzniecky R, Lowenstein D, McGuire S, Motika P, Nesbitt G, Novotny E, Paolicchi J, Parent J, Park K, Poduri A, Risch N, Sadleir L, Scheffer I, Shellhaas R, Sherr E, Shih JJ, Shinnar S, Singh R, Sirven J, Smith M, Sullivan J, Thio LL, Venkat A, Vining E, von Allmen G, Weisenberg J, Widdess-Walsh P, Winawer M
      The epilepsy phenome/genome project.
      23818435 Clinical trials (London, England), 2013 Aug. : 10(4)568-86
    • EPGP Collaborative, Abou-Khalil B, Alldredge B, Bautista J, Berkovic S, Bluvstein J, Boro A, Cascino G, Consalvo D, Cristofaro S, Crumrine P, Devinsky O, Dlugos D, Epstein M, Fahlstrom R, Fiol M, Fountain N, Fox K, French J, Freyer Karn C, Friedman D, Geller E, Glauser T, Glynn S, Haas K, Haut S, Hayward J, Helmers S, Joshi S, Kanner A, Kirsch H, Knowlton R, Kossoff E, Kuperman R, Kuzniecky R, Lowenstein D, McGuire S, Motika P, Nesbitt G, Novotny E, Ottman R, Paolicchi J, Parent J, Park K, Poduri A, Risch N, Sadleir L, Scheffer I, Shellhaas R, Sherr E, Shih JJ, Shinnar S, Singh R, Sirven J, Smith M, Sullivan J, Thio LL, Venkat A, Vining E, von Allmen G, Weisenberg J, Widdess-Walsh P, Winawer M
      The epilepsy phenome/genome project.
      23818435 Clinical trials (London, England), 2013 Aug. : 10(4)568-86
    • Friedman SD, Baker LD, Borson S, Jensen JE, Barsness SM, Craft S, Merriam GR, Otto RK, Novotny EJ, Vitiello MV
      Growth hormone-releasing hormone effects on brain -aminobutyric acid levels in mild cognitive impairment and healthy aging.
      23689947 JAMA neurology, 2013 July : 70(7)883-90 PMCID:PMC3764915
    • Friedman SD, Baker LD, Borson S, Jensen JE, Barsness SM, Craft S, Merriam GR, Otto RK, Novotny EJ, Vitiello MV
      Growth hormone-releasing hormone effects on brain γ-aminobutyric acid levels in mild cognitive impairment and healthy aging.
      23689947 JAMA neurology, 2013 July : 70(7)883-90 PMCID:PMC3764915
    • Poliachik SL, Poliakov AV, Jansen LA, McDaniel SS, Wray CD, Kuratani J, Saneto RP, Ojemann JG, Novotny EJ Jr
      Tissue localization during resective epilepsy surgery.
      23724842 Neurosurgical focus, 2013 June : 34(6)E8
    • Poliachik SL, Poliakov AV, Jansen LA, McDaniel SS, Wray CD, Kuratani J, Saneto RP, Ojemann JG, Novotny EJ Jr
      Tissue localization during resective epilepsy surgery.
      23724842 Neurosurgical focus, 2013 June : 34(6)E8
    • Nesbitt G, McKenna K, Mays V, Carpenter A, Miller K, Williams M, EPGP Investigators
      The Epilepsy Phenome/Genome Project (EPGP) informatics platform.
      22579394 International journal of medical informatics, 2013 April : 82(4)248-59 PMCID:PMC3655424
    • Winawer MR, Connors R, EPGP Investigators
      Evidence for a shared genetic susceptibility to migraine and epilepsy.
      23294289 Epilepsia, 2013 Feb. : 54(2)288-95 PMCID:PMC3566298
    • Winawer MR, Connors R, EPGP Investigators.
      Evidence for a shared genetic susceptibility to migraine and epilepsy.
      23294289 Epilepsia, 2013 Feb. : 54(2)288-95 PMCID:PMC3566298
    • Weaver KE, Chaovalitwongse WA, Novotny EJ, Poliakov A, Grabowski TG, Ojemann JG
      Local functional connectivity as a pre-surgical tool for seizure focus identification in non-lesion, focal epilepsy.
      23641233 Frontiers in neurology, 2013 : 443 PMCID:PMC3640210
    • Ishak GE, Poliakov AV, Poliachik SL, Saneto RP, Novotny EJ Jr, McDaniel S, Ojemann JG, Shaw DW, Friedman SD
      Tract-based spatial statistical analysis of diffusion tensor imaging in pediatric patients with mitochondrial disease: widespread reduction in fractional anisotropy of white matter tracts.
      22499843 AJNR. American journal of neuroradiology, 2012 Oct. : 33(9)1726-30
    • Ojemann JG, Hersonskey TY, Abeshaus S, Geyer JR, Saneto RP, Novotny EJ, Kollros P, Leary S, Holmes MD
      Epilepsy surgery after treatment of pediatric malignant brain tumors.
      22835666 Seizure : the journal of the British Epilepsy Association, 2012 Oct. : 21(8)624-30
    • Ojemann JG, Hersonskey TY, Abeshaus S, Geyer JR, Saneto RP, Novotny EJ, Kollros P, Leary S, Holmes MD
      Epilepsy surgery after treatment of pediatric malignant brain tumors.
      22835666 Seizure, 2012 Oct. : 21(8)624-30
    • Wray CD, Blakely TM, Poliachik SL, Poliakov A, McDaniel SS, Novotny EJ, Miller KJ, Ojemann JG
      Multimodality localization of the sensorimotor cortex in pediatric patients undergoing epilepsy surgery.
      22681317 Journal of neurosurgery. Pediatrics, 2012 July : 10(1)1-6 PMCID:PMC3576481
    • Wray CD, McDaniel SS, Saneto RP, Novotny EJ Jr, Ojemann JG
      Is postresective intraoperative electrocorticography predictive of seizure outcomes in children?
      22546034 Journal of neurosurgery. Pediatrics, 2012 May : 9(5)546-51
    • Khanna PC, Poliakov AV, Ishak GE, Poliachik SL, Friedman SD, Saneto RP, Novotny EJ Jr, Ojemann JG, Shaw DW
      Preserved interhemispheric functional connectivity in a case of corpus callosum agenesis.
      21553342 Neuroradiology, 2012 Feb. : 54(2)177-9
    • Strug LJ, Addis L, Chiang T, Baskurt Z, Li W, Clarke T, Hardison H, Kugler SL, Mandelbaum DE, Novotny EJ, Wolf SM, Pal DK
      The genetics of reading disability in an often excluded sample: novel loci suggested for reading disability in Rolandic epilepsy.
      22815793 PloS one, 2012 : 7(7)e40696 PMCID:PMC3399896
    • Strug LJ, Addis L, Chiang T, Baskurt Z, Li W, Clarke T, Hardison H, Kugler SL, Mandelbaum DE, Novotny EJ, Wolf SM, Pal DK
      The genetics of reading disability in an often excluded sample: novel loci suggested for reading disability in Rolandic epilepsy.
      22815793 PloS one, 2012 : 7(7)e40696 PMCID:PMC3399896
    • Wray CD, Kraemer DL, Yang T, Poliachik SL, Ko AL, Poliakov A, Hebb AO, Novotny EJ, Ojemann JG
      Freehand placement of depth electrodes using electromagnetic frameless stereotactic guidance.
      22044370 Journal of neurosurgery. Pediatrics, 2011 Nov. : 8(5)464-7
    • Negishi M, Martuzzi R, Novotny EJ, Spencer DD, Constable RT
      Functional MRI connectivity as a predictor of the surgical outcome of epilepsy.
      21801165 Epilepsia, 2011 Sept. : 52(9)1733-40 PMCID:PMC3169719
    • Killory BD, Bai X, Negishi M, Vega C, Spann MN, Vestal M, Guo J, Berman R, Danielson N, Trejo G, Shisler D, Novotny EJ Jr, Constable RT, Blumenfeld H
      Impaired attention and network connectivity in childhood absence epilepsy.
      21421063 NeuroImage, 2011 March
    • Berman R, Negishi M, Vestal M, Spann M, Chung MH, Bai X, Purcaro M, Motelow JE, Danielson N, Dix-Cooper L, Enev M, Novotny EJ, Constable RT, Blumenfeld H
      Simultaneous EEG, fMRI, and behavior in typical childhood absence seizures.
      20608963 Epilepsia, 2010 Oct. : 2011-22
    • Bai X, Vestal M, Berman R, Negishi M, Spann M, Vega C, Desalvo M, Novotny EJ, Constable RT, Blumenfeld H
      Dynamic time course of typical childhood absence seizures: EEG, behavior, and functional magnetic resonance imaging.
      20427649 The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010 Apr 28 : 5884-93
    • Zaveri HP, Pincus SM, Goncharova II, Novotny EJ, Duckrow RB, Spencer DD, Blumenfeld H, Spencer SS
      Background intracranial EEG spectral changes with anti-epileptic drug taper.
      20075002 Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2010 March : 121(3)311-7
    • Zaveri HP, Pincus SM, Goncharova II, Novotny EJ, Duckrow RB, Spencer DD, Blumenfeld H, Spencer SS
      Background intracranial EEG spectral changes with anti-epileptic drug taper.
      20075002 Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2010 March : 311-7
    • Goncharova II, Zaveri HP, Duckrow RB, Novotny EJ, Spencer SS
      Spatial distribution of intracranially recorded spikes in medial and lateral temporal epilepsies.
      19674048 Epilepsia, 2009 Dec. : 2575-85
    • Zaveri HP, Pincus SM, Goncharova II, Novotny EJ, Duckrow RB, Spencer DD, Spencer SS
      A decrease in EEG energy accompanies anti-epileptic drug taper during intracranial monitoring.
      19632096 Epilepsy research, 2009 Oct. : 153-62
    • Strug LJ, Clarke T, Chiang T, Chien M, Baskurt Z, Li W, Dorfman R, Bali B, Wirrell E, Kugler SL, Mandelbaum DE, Wolf SM, McGoldrick P, Hardison H, Novotny EJ, Ju J, Greenberg DA, Russo JJ, Pal DK
      Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4).
      19172991 European journal of human genetics : EJHG, 2009 Sept. : 1171-81
    • Spencer SS, Goncharova II, Duckrow RB, Novotny EJ, Zaveri HP
      Interictal spikes on intracranial recording: behavior, physiology, and implications.
      18479398 Epilepsia, 2008 Nov. : 1881-92
    • Dion MH, Novotny EJ Jr, Carmant L, Cossette P, Nguyen DK
      Lamotrigine therapy of epilepsy with Angelman's syndrome.
      17326790 Epilepsia, 2007 March : 593-6
    • Shetty-Alva N, Novotny EJ, Shetty T, Kuo PH
      Positron emission tomography in Rasmussen's encephalitis.
      17275663 Pediatric neurology, 2007 Feb. : 112-4
    • Pearl PL, Capp PK, Novotny EJ, Gibson KM
      Inherited disorders of neurotransmitters in children and adults.
      16298354 Clinical biochemistry, 2005 Dec. : 1051-8
    • McNally KA, Paige AL, Varghese G, Zhang H, Novotny EJ Jr, Spencer SS, Zubal IG, Blumenfeld H
      Localizing value of ictal-interictal SPECT analyzed by SPM (ISAS).
      16146441 Epilepsia, 2005 Sept. : 1450-64
    • Safriel Y, Pol-Rodriguez M, Novotny EJ, Rothman DL, Fulbright RK
      Reference values for long echo time MR spectroscopy in healthy adults.
      15956513 AJNR. American journal of neuroradiology, 2005 June : 1439-45
    • Trübel H, Herman P, Kampmann C, Huth R, Maciejewski PK, Novotny E, Hyder F
      A novel approach for selective brain cooling: implications for hypercapnia and seizure activity.
      15185071 Intensive care medicine, 2004 Sept. : 1829-33
    • Blumenfeld H, McNally KA, Vanderhill SD, Paige AL, Chung R, Davis K, Norden AD, Stokking R, Studholme C, Novotny EJ Jr, Zubal IG, Spencer SS
      Positive and negative network correlations in temporal lobe epilepsy.
      15084494 Cerebral cortex (New York, N.Y. : 1991), 2004 Aug. : 892-902
    • Lai JC, White BK, Buerstatte CR, Haddad GG, Novotny EJ Jr, Behar KL
      Chronic hypoxia in development selectively alters the activities of key enzymes of glucose oxidative metabolism in brain regions.
      12718448 Neurochemical research, 2003 June : 933-40
    • Trübel HK, Novotny E, Lister G
      Outcome of coma in children.
      12806258 Current opinion in pediatrics, 2003 June : 283-7
    • Nguyen D, Singh S, Zaatreh M, Novotny E, Levy S, Testa F, Spencer SS
      Hypothalamic hamartomas: seven cases and review of the literature.
      12791326 Epilepsy & behavior : E&B, 2003 June : 246-58
    • Motamedi M, Nguyen DK, Zaatreh M, Singh SP, Westerveld M, Thompson JL, Mattson R, Blumenfeld H, Novotny E, Spencer SS
      Levetiracetam efficacy in refractory partial-onset seizures, especially after failed epilepsy surgery.
      12558576 Epilepsia, 2003 Feb. : 211-4
    • Pearl PL, Novotny EJ, Acosta MT, Jakobs C, Gibson KM
      Succinic semialdehyde dehydrogenase deficiency in children and adults.
      12891657 Annals of neurology, 2003 : S73-80
    • Novotny EJ Jr, Fulbright RK, Pearl PL, Gibson KM, Rothman DL
      Magnetic resonance spectroscopy of neurotransmitters in human brain.
      12891651 Annals of neurology, 2003 : S25-31
    • Zaatreh MM, Spencer DD, Thompson JL, Blumenfeld H, Novotny EJ, Mattson RH, Spencer SS
      Frontal lobe tumoral epilepsy: clinical, neurophysiologic features and predictors of surgical outcome.
      12102675 Epilepsia, 2002 July : 727-33
    • Butchko HH, Stargel WW, Comer CP, Mayhew DA, Benninger C, Blackburn GL, de Sonneville LM, Geha RS, Hertelendy Z, Koestner A, Leon AS, Liepa GU, McMartin KE, Mendenhall CL, Munro IC, Novotny EJ, Renwick AG, Schiffman SS, Schomer DL, Shaywitz BA, Spiers PA, Tephly TR, Thomas JA, Trefz FK
      Aspartame: review of safety.
      12180494 Regulatory toxicology and pharmacology : RTP, 2002 April : S1-93
    • Spencer SS, Katz A, Ebersole J, Novotny E, Mattson R
      Ictal EEG changes with corpus callosum section.
      8504788 Epilepsia, 1993 May : 34(3)568-73

Overview

Board Certification(s)

Epilepsy
Pediatrics
Neurology with Special Qualification in Child Neurology

Medical/Professional School

St. Louis University School of Medicine, Saint Louis, MO

Residency

Stanford University School of Medicine, Stanford, CA
Uc Davis School Of Medicine, Sacramento, CA

Fellowship

Stanford University School of Medicine, Stanford, CA
Yale University School of Medicine GME, New Haven, CT

Clinical Interests

clinical neurophysiology and epilepsy surgery in children; neuro-metabolic disorders, developmental neuroimaging; and multimodal neuroimaging in pediatric epilepsy

Research Focus Area

Neuroscience / Neurodevelopment