Kenneth A Schenkman, MD, PhD

Kenneth A Schenkman, MD, PhD

Critical Care, Pediatric Intensive Care Unit (PICU)

On staff since November 1998

Academic Title: Associate Professor

Research Center: Center for Clinical and Translational Research

  • Biography

    Kenneth A. Schenkman, MD, PhD, is an attending physician in the Pediatric Intensive Care Units at Seattle Childrens Hospital and Harborview Medical Center. He is an Associate Professor of Pediatrics and Anesthesiology and Adjunct Associate Professor of Bioengineering at the University of Washington School of Medicine. Dr. Schenkman received his MD from Indiana University and completed a pediatrics residency at the Childrens Hospital of Pittsburgh, where he also served as Chief Resident.

    Dr. Schenkman trained in pediatric critical care at Seattle Childrens and received a PhD in Bioengineering from the University of Washington. He has an active research program developing optical spectroscopic technologies for clinical assessment of intracellular oxygenation and mitochondrial function. Dr. Schenkman has several U.S. patents for his pioneering work on developing an intracellular oxygen monitor. Schenkman has published dozens of manuscripts and abstracts in the field of optical spectroscopy for physiologic and clinical applications, and has published several book chapters on pediatric critical care topics. He also has been an active reviewer for journals in the fields of medicine, physiology and biomedical optics.

  • Patient Testimonials

    Be the first to recommend Kenneth A Schenkman, MD, PhD

  • Publications

    Manuscripts in Refereed Journals

    • Kenneth A. Schenkman, MD, PhD
      Photon Path Depth in Tissue Phantoms: A Comparison of Visible and Near-Infrared Wavelengths
      Proceedings of the SPIE Symposium on Biomedical Optics, 2014 : 8945
    • Kenneth A. Schenkman, MD, PhD
      Muscle oxygenation measurement in humans by noninvasive optical spectroscopy and locally weight regression
      Analytica Chimica Acta, 2013 : 78527-33 PMCID:490057
    • Cohen GA, Permut LC, Arakaki LS, Ciesielski WA, McMullan DM, Parrish AR, Schenkman KA
      Direct optical measurement of intraoperative myocardial oxygenation during congenital heart surgery.
      21508828 ASAIO journal (American Society for Artificial Internal Organs : 1992), 2011 July : 57(4)314-7

    Other Publications

    • Arakaki LS, Schenkman KA, Ciesielski WA, Shaver JM
      Muscle oxygenation measurement in humans by noninvasive optical spectroscopy and Locally Weighted Regression.
      23764440 Analytica chimica acta, 2013 Jun 27 : 78527-33 PMCID:PMC3772676
    • Arakaki LS, Schenkman KA, Ciesielski WA, Shaver JM
      Muscle oxygenation measurement in humans by noninvasive optical spectroscopy and Locally Weighted Regression.
      23764440 Analytica chimica acta, 2013 Jun 27 : 78527-33 PMCID:PMC3772676
    • Cohen GA, Permut LC, Arakaki LS, Ciesielski WA, McMullan DM, Parrish AR, Schenkman KA
      Direct optical measurement of intraoperative myocardial oxygenation during congenital heart surgery.
      21508828 ASAIO journal (American Society for Artificial Internal Organs : 1992), 2011 July : 314-7
    • Arakaki LS, Ciesielski WA, Thackray BD, Feigl EO, Schenkman KA
      Simultaneous optical spectroscopic measurement of hemoglobin and myoglobin saturations and cytochrome aa3 oxidation in vivo.
      20828433 Applied spectroscopy, 2010 Sept. : 973-9
    • Amara CE, Marcinek DJ, Shankland EG, Schenkman KA, Arakaki LS, Conley KE
      Mitochondrial function in vivo: spectroscopy provides window on cellular energetics.
      18930151 Methods (San Diego, Calif.), 2008 Dec. : 312-8
    • Amara CE, Marcinek DJ, Shankland EG, Schenkman KA, Arakaki LS, Conley KE
      Mitochondrial function in vivo: spectroscopy provides window on cellular energetics.
      18930151 Methods (San Diego, Calif.), 2008 Dec. : 312-8
    • Kruse SE, Watt WC, Marcinek DJ, Kapur RP, Schenkman KA, Palmiter RD
      Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy.
      18396137 Cell metabolism, 2008 April : 312-20
    • Schenkman KA
      Clinical data collection in the information era.
      17989567 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2007 Nov. : 588-9
    • Schenkman KA
      Clinical data collection in the information era.
      17989567 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2007 Nov. : 588-9
    • Marcinek DJ, Amara CE, Matz K, Conley KE, Schenkman KA
      Wavelength shift analysis: a simple method to determine the contribution of hemoglobin and myoglobin to in vivo optical spectra.
      17650380 Applied spectroscopy, 2007 June : 665-9
    • Schenkman KA, Arakaki LS, Ciesielski WA, Beard DA
      Optical spectroscopy demonstrates elevated intracellular oxygenation in an endotoxic model of sepsis in the perfused heart.
      17505311 Shock (Augusta, Ga.), 2007 June : 695-700
    • Roberts JS, Vavilala MS, Schenkman KA, Shaw D, Martin LD, Lam AM
      Cerebral hyperemia and impaired cerebral autoregulation associated with diabetic ketoacidosis in critically ill children.
      16763506 Critical care medicine, 2006 Aug. : 2217-23
    • Ejike JC, Schenkman KA, Seidel K, Ramamoorthy C, Roberts JS
      Cerebral oxygenation in neonatal and pediatric patients during veno-arterial extracorporeal life support.
      16446597 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2006 March : 154-8
    • Marcinek DJ, Schenkman KA, Ciesielski WA, Lee D, Conley KE
      Reduced mitochondrial coupling in vivo alters cellular energetics in aged mouse skeletal muscle.
      16254011 The Journal of physiology, 2005 Dec 1 : 467-73
    • Ejike JC, Arakaki LS, Beard DA, Ciesielski WA, Feigl EO, Schenkman KA
      Myocardial oxygenation and adenosine release in isolated guinea pig hearts during changes in contractility.
      15591100 American journal of physiology. Heart and circulatory physiology, 2005 May : H2062-7
    • Ejike JC, Arakaki LS, Beard DA, Ciesielski WA, Feigl EO, Schenkman KA
      Myocardial oxygenation and adenosine release in isolated guinea pig hearts during changes in contractility.
      15591100 American journal of physiology. Heart and circulatory physiology, 2005 May : H2062-7
    • Marcinek DJ, Schenkman KA, Ciesielski WA, Conley KE
      Mitochondrial coupling in vivo in mouse skeletal muscle.
      14522819 American journal of physiology. Cell physiology, 2004 Feb. : C457-63
    • Schenkman KA, Beard DA, Ciesielski WA, Feigl EO
      Comparison of buffer and red blood cell perfusion of guinea pig heart oxygenation.
      12869374 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1819-25
    • Beard DA, Schenkman KA, Feigl EO
      Myocardial oxygenation in isolated hearts predicted by an anatomically realistic microvascular transport model.
      12869375 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1826-36
    • Schenkman KA, Beard DA, Ciesielski WA, Feigl EO
      Comparison of buffer and red blood cell perfusion of guinea pig heart oxygenation.
      12869374 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1819-25
    • Beard DA, Schenkman KA, Feigl EO
      Myocardial oxygenation in isolated hearts predicted by an anatomically realistic microvascular transport model.
      12869375 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1826-36
    • Marcinek DJ, Ciesielski WA, Conley KE, Schenkman KA
      Oxygen regulation and limitation to cellular respiration in mouse skeletal muscle in vivo.
      12775561 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1900-8
    • Marcinek DJ, Ciesielski WA, Conley KE, Schenkman KA
      Oxygen regulation and limitation to cellular respiration in mouse skeletal muscle in vivo.
      12775561 American journal of physiology. Heart and circulatory physiology, 2003 Nov. : H1900-8
    • Okpechi JC, Schenkman KA
      Bronchoesophageal fistula after gastrostomy tube removal by the "cut and push" method.
      12838242 Gastrointestinal endoscopy, 2003 July : 134-7
    • Okpechi JC, Schenkman KA
      Bronchoesophageal fistula after gastrostomy tube removal by the "cut and push" method.
      12838242 Gastrointestinal endoscopy, 2003 July : 134-7
    • Maier SK, Westenbroek RE, Schenkman KA, Feigl EO, Scheuer T, Catterall WA
      An unexpected role for brain-type sodium channels in coupling of cell surface depolarization to contraction in the heart.
      11891345 Proceedings of the National Academy of Sciences of the United States of America, 2002 Mar 19 : 4073-8
    • Sweet IR, Khalil G, Wallen AR, Steedman M, Schenkman KA, Reems JA, Kahn SE, Callis JB
      Continuous measurement of oxygen consumption by pancreatic islets.
      12450449 Diabetes technology & therapeutics, 2002 : 661-72

  • Research Funding

    Grant Title Grantor Amount Award Date
    Assessment of muscle oxygen consumption in children with congenital heart disease UW Royalty Research Fund $39,736 2015 - 2016
    Muscle oxygenation as an indicator for red blood cell transfusion need CCTR TRIPP $50,000 2013 - 2014
    Muscle oxygenation for assessment of tissue perfusion during extracorporeal life support American Heart Association $140,000 2013 - 2014
    Development of an instrument to track oxygen from blood to mitochondria in vivo NIH $563,025 2013 - 2016
    Optical measurement of cellular oxygenation in shock and resuscitation NIH $429,000 2010 - 2012
    Noninvasive cellular oxygen monitor for shock Coulter Foundation $55,127.00 2009 - 2010
    Translational center for in vivo mitochondrial medicine NIH $1,798,509.00 2009 - 2011
    Noninvasive Clinical Monitor for Early Detection of Shock WA Life Sciences Discovery Fund $150,000.00 2009 - 2010
    Cellular oxygenation in traumatic shock Seattle Medic One Foundation, $106,291.00 2009 - 2010
    Noninvasive shock monitor for trauma and critically ill patients UW Technology Gap Innovation Fund $50,000.00 2008 - 2009
    MR and optical diagnosis of muscle metabolism and function NIH $1,678,900.00 2007 - 2012

Overview

Board Certification(s)

Pediatric Critical Care Medicine

Medical/Professional School

Indiana Univ/Purdue University-Indianapolis, Indianapolis, IN
University of Washington, Seattle, WA

Residency

Children's Hospital of Pittsburgh, Pittsburgh, PA

Fellowship

Seattle Children's Hospital, Seattle, WA

Research Focus Area

Therapeutic Trials, Translational research, observational studies, investigator-initiated interventional studies