Ikuyo Yamaguchi, MD, PhD

Ikuyo Yamaguchi, MD, PhD


On staff since September 2006

Academic Title: Assistant Professor, Pediatrics

Research Center: Center for Developmental Biology and Regenerative Medicine

Language (Other than English): Japanese

  • Ikuyo Yamaguchi, MD, PhD, is an attending physician at Seattle Children’s and an Assistant Professor of Pediatrics at the University of Washington School of Medicine. She earned her MD from Kumamoto University and her PhD from Kurume University in Japan.

    Dr. Yamaguchi completed her pediatric training at Georgetown University Medical Center in Washington, D.C. and her pediatric nephrology fellowship at Seattle Children’s. As a clinician-scientist working in basic science research she is focusing on angiogenic factors such as placental growth factor and vascular endothelial cadherin (the major adhesion molecule at the adherens junctions between endothelial cells), investigating how these factors affect the progression of chronic kidney disease. Her clinical interests include hypertension and chronic kidney disease in children and she works in the hypertension clinic with Dr. Joseph Flynn and regional clinics in Everett, WA.

    • Janet Bremerton, WA 07.16.12

      Dr Yamaguchi has been a wonderful addition to our family. Her care and compassion toward our daughter is wonderful. She is gentle and encouraging as we seek the best way to bring our daughter through a journey of prime health and recovery from end stage renal failure.

    • Yamaguchi I, Lopez-Guisa JM, Cai X, Collins SJ, Okamura DM, Eddy AA
      Endogenous urokinase lacks antifibrotic activity during progressive renal injury.
      17356128 American journal of physiology. Renal physiology , 2007 July : F12-9
    • Felder RA, Sanada H, Xu J, Yu PY, Wang Z, Watanabe H, Asico LD, Wang W, Zheng S, Yamaguchi I, Williams SM, Gainer J, Brown NJ, Hazen-Martin D, Wong LJ, Robillard JE, Carey RM, Eisner GM, Jose PA
      G protein-coupled receptor kinase 4 gene variants in human essential hypertension.
      11904438 Proceedings of the National Academy of Sciences of the United States of America , 2002 Mar. 19 : 3872-7


Medical/Professional School

Kumamoto University School of Medicine, Kumamoto
Kurume University, Kurume


Pediatrics, Kurume University, Kurume
Pediatrics, Georgetown University Hospital, Washington


Pediatric Nephrology, Children's Hospital and Regional Medical Center, Seattle

Clinical Interests

glomerulo nephritis, hypertension renal fibrosis, renal microcirculation

Research Focus Area

Translational Research