Profile

Douglas S. Hawkins, MD

Douglas S. Hawkins, MD

Hematology-Oncology

On staff since February 1996

Children's Title: Division Chief

Academic Title: Professor of Pediatrics, Hematology/Oncology Division

Research Center: Center for Clinical and Translational Research

"I feel exceptionally fortunate to work with some of the smartest people I know. Each day brings new opportunities to learn from my colleagues, patients and families. By the nature of our work in Hematology/Oncology, we know the importance of what we do every day. I am continually impressed that we have the opportunity to change the lives of children and young adults for the better, both with good clinical care and by leading clinical and translational research efforts. My hope is that the clinical research we do today will lead to more effective treatments with fewer side effects for children and young adults in the future."

  • Douglas S. Hawkins, MD, is the Hematology/Oncology Division Chief, Associate Director of the Center for Clinical and Translational Research at Seattle Childrens Hospital (SCH), clinician at SCH, and Professor of Pediatrics at the University of Washington School of Medicine.

    Dr. Hawkins is a leader in the Children's Oncology Group (COG). He is the Chair of the Soft Tissue Sarcoma Committee, which oversees the conduct of biology studies and clinical trials for rhabdomyosarcoma and other soft tissue sarcomas across North America. He is a member of the COG Bone Tumor Steering Committee. He is also the Chair of the COG Scientific and Discipline Chairs Committee. Dr. Hawkins has focused on clinical research, particularly in the treatment of pediatric sarcomas. He has been the chair of two COG clinical trials, one for Ewing sarcoma and another for rhabdomyosarcoma. He chairs the international EURO EWING Consortium External Advisory Board.

    • Kelly Seattle, WA 07.09.13

      Our sons life was saved by Dr. Hawkins and his incredible team. From the confusion and shock of the initial diagnosis to end of treatment celebration, Dr. Hawkins not only walked by our son's side every step of the way, he personally invested in our entire family. Dr. Hawkins is equal parts honest, courageous, brilliant, and compassionate. Dr. Hawkins and his team are an inspiration, and our family is eternally grateful for all that they do!

    • Rahil Kent, WA 10.19.12

      Dr. Hawkins is a professional, kind and caring doctor with a large expertise in treating childhood cancer. Upon our orientation at Children's, he was the key person that explained the medicines, treatment plan, schedule and expectations. He explained differences in treatment plans in Europe and North America. He presented our scans, biopsy and test results making sure that we understood everything. He has done a good job and our son is now cured of cancer. Thank you Dr. Hawkins and the expert staff at Seattle Children's!

    • Heather Snoqualmie, WA 09.25.12

      Dr. Hawkins and his incredible team saved out daughters life. Dr. Hawkins had the insight to look past the original diagnosis given to our daughter. She was diagnosed with TEC at 15 months with a HCT of 7. This was not life sustaining. He and his team consulted, worked, planned and communitcated with each other and our family to come up with the best course of treatment. I cant thank Dr. Hawkins and Seattle Children's enough. They preform miracles everyday!

    • janice wenatchee, wa. 02.13.12

      Dr. Hawkins works around the clock to give our children the best care. I am happy to say my son is a bone cancer survivor. I appreciated how Dr. Hawkins worked to make sure the side affects from the chemo where addressed as well as its progress. Thank you so much, Janice B.

    • elce kent,washinton 09.28.11

      Dr. Hawkins saved my daughters life,who was diagnosed with stage 4 alveolar rhabdomyosarcoma last year.My daughter is cancer free for almost three months now because of Dr. Hawkins and his team.God bless them.God is Good.

    • Becky seattle ,wa 06.16.11

      I was a distraught parent when my daughter was diagnosed at 15 with Hodgkin's lymphoma. he spent the time to make me feel at ease and encouraged me to participate in her care . i didn't have a clue what i should do . he made me feel comfortable to ask a lot of questions, and he answered with reassurance and calmness . He worked closely with me as a parent as well as his colleagues to give her the best care she could get. he responded as quickly as possible to all of my phone calls. He is a very humble man for all of his qualifications . there are a lot of people who look up to him , if he only knew how many .... many thanks!! we pray for his continued success!!

    • Lynora Ketchikan, Alaska 04.14.11

      Five years ago, my 8 1/2 year old son was diagnosed with Hodgkin's Lymphoma. I remember Dr Hawkins looking me right in the eye and saying, "This cancer is very, very, VERY curable." I clung to his words, and today we are celebrating my son's 14th birthday. Thank you Dr. Hawkins, and Children's, for assisting God in our son's healing!

    • Kathleen Seattle, WA 03.30.11

      If you are seeing Dr. Hawkins, you've likely heard the worst thing you will ever hear: your child has cancer. If that's the case, thank God you're seeing Dr. Hawkins! My son nearly died before he was diagnosed in 1997 at age 2 with Burkitt's Lymphoma. We were so grateful to have Dr. Hawkins on his team. He's honest, clear, compassionate and simply the most knowledgeable physician treating kids today. My son is 16 now, rowing crew and making the honor roll!

    • camille seattle washington 02.17.11

      Dr. Hawkins is my personal Hero! I was two weeks short of dying when he took over. I had stage 4 hodgkins lymphoma I was 15 yrs old. I am now 20 and I have a beautiful son and have been in remisson for 5 yrs now. Thank you Dr. Hawkins!

    • Lynora Ketchikan, Alaska 04.14.11

      Five years ago, my 8 1/2 year old son was diagnosed with Hodgkin's Lymphoma. I remember Dr Hawkins looking me right in the eye and saying, "This cancer is very, very, VERY curable." I clung to his words, and today we are celebrating my son's 14th birthday. Thank you Dr. Hawkins, and Children's, for assisting God in our son's healing!

    • Tammy Maple Valley, WA 12.10.10

      Dr. Doug Hawkins and Dr. Lawrence Cooper diagnosed our son Eric as a Lg Cell Lymphoma patient in early 1997 when he was 10. Eric recently had his 24th Birthday, THANKS TO THEIR KNOWLEDGE AND CARE. He is a SURVIVOR!! Thank you to them and all the wonderful nurses that made that hard time bearable. Sincerely, Eric's Mom & Dad

  • Award Name Award Description Awarded By Award Date
    SEATTLE'S TOP DOCTOR - 2018 Seattle Magazine 2018
    SEATTLE'S TOP DOCTOR - 2017 Seattle Magazine 2017
    SEATTLE MAGAZINE TOP DOCTOR - 2016 Seattle Magazine 2016
    Seattles Top Doctor 2016 Seattle Met Magazine 2016
    SEATTLE MAGAZINE TOP DOCTOR - 2015 Seattle Magazine 2015
    Newsweek Health: Top Cancer Doctors 2015 Newsweek 2015
    SEATTLE MAGAZINE TOP DOCTOR - 2014 Seattle Magazine 2014
    Seattle's Top Doc Seattle Met Magazine 2013
    Seattle Magazine Top Doctor - 2013 Seattle Magazine 2013
    U.S. News Top Doctor U.S. News and World Report 2012
    Seattle Magazine Top Doctor - 2012 Seattle Magazine Top Doctor - 2012 Seattle Magazine 2012
    • Teot LA, Schneider M, Thorner AR, Tian J, Chi YY, Ducar M, Lin L, Wlodarski M, Grier HE, Fletcher CDM, van Hummelen P, Skapek SX, Hawkins DS, Wagers AJ, Rodriguez-Galindo C, Hettmer S
      Clinical and mutational spectrum of highly differentiated, paired box 3:forkhead box protein o1 fusion-negative rhabdomyosarcoma: A report from the Children's Oncology Group.
      29461635 Cancer , 2018 May 1 : 124(9)1973-1981 PMCID: PMC5910184
    • Laetsch TW, Roy A, Xu L, Black JO, Coffin CM, Chi YY, Tian J, Spunt SL, Hawkins DS, Bridge JA, Parsons DW, Skapek SX
      Undifferentiated sarcomas in children harbor clinically-relevant oncogenic fusions and gene copy-number alterations: A report from the Children's Oncology Group.
      29691299 Clinical cancer research : an official journal of the American Association for Cancer Research , 2018 Apr, 24
    • Ronsley R, Rassekh SR, Shen Y, Lee AF, Jantzen C, Halparin J, Albert C, Hawkins DS, Amed S, Rothstein R, Mungall AJ, Dix D, Blair G, Nadel H, Jones SJM, Laskin J, Marra MA, J Deyell R
      Application of genomics to identify therapeutic targets in recurrent pediatric papillary thyroid carcinoma.
      29610391 Cold Spring Harbor molecular case studies , 2018 Apr, : 4(2) PMCID: PMC5880264
    • Laetsch TW, DuBois SG, Mascarenhas L, Turpin B, Federman N, Albert CM, Nagasubramanian R, Davis JL, Rudzinski E, Feraco AM, Tuch BB, Ebata KT, Reynolds M, Smith S, Cruickshank S, Cox MC, Pappo AS, Hawkins DS
      Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study.
      29606586 The Lancet. Oncology , 2018 Mar. 29
    • Drilon A, Laetsch TW, Kummar S, DuBois SG, Lassen UN, Demetri GD, Nathenson M, Doebele RC, Farago AF, Pappo AS, Turpin B, Dowlati A, Brose MS, Mascarenhas L, Federman N, Berlin J, El-Deiry WS, Baik C, Deeken J, Boni V, Nagasubramanian R, Taylor M, Rudzinski ER, Meric-Bernstam F, Sohal DPS, Ma PC, Raez LE, Hechtman JF, Benayed R, Ladanyi M, Tuch BB, Ebata K, Cruickshank S, Ku NC, Cox MC, Hawkins DS, Hong DS, Hyman DM
      Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.
      29466156 The New England journal of medicine , 2018 Feb. 22 : 378(8)731-739 PMCID: PMC5857389
    • Davis JL, Lockwood CM, Albert CM, Tsuchiya K, Hawkins DS, Rudzinski ER
      Infantile NTRK-associated Mesenchymal Tumors.
      28683589 Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2018 Jan. : 21(1)68-78
    • Rudzinski ER, Anderson JR, Chi YY, Gastier-Foster JM, Astbury C, Barr FG, Skapek SX, Hawkins DS, Weigel BJ, Pappo A, Meyer WH, Arnold MA, Teot LA, Parham DM
      Histology, fusion status, and outcome in metastatic rhabdomyosarcoma: A report from the Children's Oncology Group.
      28521080 Pediatric blood and cancer , 2017 Dec. : 64(12) PMCID: PMC5647228
    • Wang X, Sun CL, Hageman L, Smith K, Singh P, Desai S, Hawkins DS, Hudson MM, Mascarenhas L, Neglia JP, Oeffinger KC, Ritchey AK, Robison LL, Villaluna D, Landier W, Bhatia S
      Clinical and Genetic Risk Prediction of Subsequent CNS Tumors in Survivors of Childhood Cancer: A Report From the COG ALTE03N1 Study.
      28976792 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2017 Nov. 10 : 35(32)3688-3696 PMCID: PMC5678343
    • Pinto N, Park JR, Murphy E, Yearley J, McClanahan T, Annamalai L, Hawkins DS, Rudzinski ER
      Patterns of PD-1, PD-L1, and PD-L2 expression in pediatric solid tumors.
      28488345 Pediatric blood and cancer , 2017 Nov. : 64(11)
    • Ren T, Piperdi S, Koirala P, Park A, Zhang W, Ivenitsky D, Zhang Y, Villanueva-Siles E, Hawkins DS, Roth M, Gorlick R
      CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression.
      29152125 Oncotarget , 2017 Oct. 20 : 8(50)87848-87859 PMCID: PMC5675677
    • Davis LE, Janeway KA, Weiss AR, Chen YE, Scharschmidt TJ, Krailo M, Glade Bender JL, Kopp LM, Patel SR, Schwartz GK, Horvath LE, Hawkins DS, Chuk MK, Reinke DK, Gorlick RG, Randall RL
      Clinical trial enrollment of adolescents and young adults with sarcoma.
      28493547 Cancer , 2017 Sept. 15 : 123(18)3434-3440 PMCID: PMC5650232
    • Ermoian RP, Breneman J, Walterhouse DO, Chi YY, Meza J, Anderson J, Hawkins DS, Hayes-Jordan AA, Parham DM, Yock TI, Donaldson SS, Wolden SL
      45 Gy is not sufficient radiotherapy dose for Group III orbital embryonal rhabdomyosarcoma after less than complete response to 12 weeks of ARST0331 chemotherapy: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
      28548706 Pediatric blood and cancer , 2017 Sept. : 64(9) PMCID: PMC5568701
    • Gupta AA, Chi YY, Anderson JR, Lyden E, Weigel B, Arndt C, Meyer WH, Rosenberg A, Hawkins DS
      Patterns of chemotherapy-induced toxicities and outcome in children and adolescents with metastatic rhabdomyosarcoma: A report from the Children's Oncology Group.
      28333415 Pediatric blood and cancer , 2017 Sept. : 64(9) PMCID: PMC5567865
    • Walterhouse DO, Pappo AS, Meza JL, Breneman JC, Hayes-Jordan A, Parham DM, Cripe TP, Anderson JR, Meyer WH, Hawkins DS
      Reduction of cyclophosphamide dose for patients with subset 2 low-risk rhabdomyosarcoma is associated with an increased risk of recurrence: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
      28211936 Cancer , 2017 June 15 : 123(12)2368-2375 PMCID: PMC5662934
    • Ferrari A, Chi YY, De Salvo GL, Orbach D, Brennan B, Randall RL, McCarville MB, Black JO, Alaggio R, Hawkins DS, Bisogno G, Spunt SL
      Surgery alone is sufficient therapy for children and adolescents with low-risk synovial sarcoma: A joint analysis from the European paediatric soft tissue sarcoma Study Group and the Children's Oncology Group.
      28391003 European journal of cancer (Oxford, England : 1990) , 2017 June : 781-6 PMCID: PMC5567853
    • Cross NM, Stanescu AL, Rudzinski ER, Hawkins DS, Parisi MT
      Vaginal Ewing Sarcoma: An Uncommon Clinical Entity in Pediatric Patients.
      28589056 Journal of clinical imaging science , 2017 : 717 PMCID: PMC5433652
    • Marina NM, Smeland S, Bielack SS, Bernstein M, Jovic G, Krailo MD, Hook JM, Arndt C, van den Berg H, Brennan B, Brichard B, Brown KLB, Butterfass-Bahloul T, Calaminus G, Daldrup-Link HE, Eriksson M, Gebhardt MC, Gelderblom H, Gerss J, Goldsby R, Goorin A, Gorlick R, Grier HE, Hale JP, Hall KS, Hardes J, Hawkins DS, Helmke K, Hogendoorn PCW, Isakoff MS, Janeway KA, Jürgens H, Kager L, Kühne T, Lau CC, Leavey PJ, Lessnick SL, Mascarenhas L, Meyers PA, Mottl H, Nathrath M, Papai Z, Randall RL, Reichardt P, Renard M, Safwat AA, Schwartz CL, Stevens MCG, Strauss SJ, Teot L, Werner M, Sydes MR, Whelan JS
      Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial.
      27569442 The Lancet. Oncology , 2016 Oct. : 17(10)1396-1408 PMCID: PMC5052459
    • Xu L, Wilson RA, Laetsch TW, Oliver D, Spunt SL, Hawkins DS, Skapek SX
      Potential pitfalls of mass spectrometry to uncover mutations in childhood soft tissue sarcoma: A report from the Children's Oncology Group.
      27642091 Scientific reports , 2016 Sept. 19 : 633429 PMCID: PMC5027578
    • Black JO, Coffin CM, Parham DM, Hawkins DS, Speights RA, Spunt SL
      Opportunities for Improvement in Pathology Reporting of Childhood Nonrhabdomyosarcoma Soft Tissue Sarcomas:  A Report From Children's Oncology Group (COG) Study ARST0332.
      27510717 American journal of clinical pathology , 2016 Sept. : 146(3)328-38
    • Lagmay JP, Krailo MD, Dang H, Kim A, Hawkins DS, Beaty O 3rd, Widemann BC, Zwerdling T, Bomgaars L, Langevin AM, Grier HE, Weigel B, Blaney SM, Gorlick R, Janeway KA
      Outcome of Patients With Recurrent Osteosarcoma Enrolled in Seven Phase II Trials Through Children's Cancer Group, Pediatric Oncology Group, and Children's Oncology Group: Learning From the Past to Move Forward.
      27400942 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2016 Sept. 1 : 34(25)3031-8 PMCID: PMC5012712
    • Sankaran H, Danysh HE, Scheurer ME, Okcu MF, Skapek SX, Hawkins DS, Spector LG, Erhardt EB, Grufferman S, Lupo PJ
      The Role of Childhood Infections and Immunizations on Childhood Rhabdomyosarcoma: A Report From the Children's Oncology Group.
      27198935 Pediatric blood and cancer , 2016 Sept. : 63(9)1557-62 PMCID: PMC4955701
    • Serrero G, Hawkins DM, Bejarano PA, Ioffe O, Tkaczuk KR, Elliott RE, Head JF, Phillips J, Godwin AK, Weaver J, Hicks D, Yue B
      Determination of GP88 (progranulin) expression in breast tumor biopsies improves the risk predictive value of the Nottingham Prognostic Index.
      27501955 Diagnostic pathology , 2016 Aug. 8 : 11(1)71 PMCID: PMC4977669
    • Vo KT, Edwards JV, Epling CL, Sinclair E, Hawkins DS, Grier HE, Janeway KA, Barnette P, McIlvaine E, Krailo MD, Barkauskas DA, Matthay KK, Womer RB, Gorlick RG, Lessnick SL, Mackall CL, DuBois SG
      Impact of Two Measures of Micrometastatic Disease on Clinical Outcomes in Patients with Newly Diagnosed Ewing Sarcoma: A Report from the Children's Oncology Group.
      26861456 Clinical cancer research : an official journal of the American Association for Cancer Research , 2016 July 15 : 22(14)3643-50 PMCID: PMC4947459
    • Hingorani P, Janeway K, Crompton BD, Kadoch C, Mackall CL, Khan J, Shern JF, Schiffman J, Mirabello L, Savage SA, Ladanyi M, Meltzer P, Bult CJ, Adamson PC, Lupo PJ, Mody R, DuBois SG, Parsons DW, Khanna C, Lau C, Hawkins DS, Randall RL, Smith M, Sorensen PH, Plon SE, Skapek SX, Lessnick S, Gorlick R, Reed DR
      Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop.
      27132463 Cancer genetics , 2016 May : 209(5)182-94 PMCID: PMC5497490
    • Arnold MA, Anderson JR, Gastier-Foster JM, Barr FG, Skapek SX, Hawkins DS, Raney RB Jr, Parham DM, Teot LA, Rudzinski ER, Walterhouse DO
      Histology, Fusion Status, and Outcome in Alveolar Rhabdomyosarcoma With Low-Risk Clinical Features: A Report From the Children's Oncology Group.
      26756883 Pediatric blood and cancer , 2016 Apr, : 63(4)634-9 PMCID: PMC4755849
    • Richards MK, Dahl JP, Gow K, Goldin AB, Doski J, Goldfarb M, Nuchtern J, Langer M, Beierle EA, Vasudevan S, Hawkins DS, Parikh SR
      Factors Associated With Mortality in Pediatric vs Adult Nasopharyngeal Carcinoma.
      26769566 JAMA otolaryngology-- head and neck surgery , 2016 Mar. : 142(3)217-22
    • Vo KT, Edwards JV, Epling CL, Sinclair E, Hawkins DS, Grier HE, Janeway KA, Barnette P, McIlvaine E, Krailo M, Barkauskas DA, Matthay KK, Womer RB, Gorlick R, Lessnick SL, Mackall CL, Dubois SG
      Impact of Two Measures of Micrometastatic Disease on Clinical Outcomes in Patients with Newly Diagnosed Ewing Sarcoma: A Report from the Children's Oncology Group.
      26861456 Clinical cancer research : an official journal of the American Association for Cancer Research , 2016 Feb. 9
    • Pinto N, Hawkins DS
      Second Malignant Neoplasms in Rhabdomyosarcoma: Victims of Our Own Success or an Underlying Genetic Predisposition Syndrome?
      26505490 Pediatric blood and cancer , 2016 Feb. : 63(2)189-90
    • Weigel BJ, Lyden E, Anderson JR, Meyer WH, Parham DM, Rodeberg DA, Michalski JM, Hawkins DS, Arndt CA
      Intensive Multiagent Therapy, Including Dose-Compressed Cycles of Ifosfamide/Etoposide and Vincristine/Doxorubicin/Cyclophosphamide, Irinotecan, and Radiation, in Patients With High-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group.
      26503200 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2016 Jan. 10 : 34(2)117-22 PMCID: PMC5070550
    • Wolden SL, Lyden ER, Arndt CA, Hawkins DS, Anderson JR, Rodeberg DA, Morris CD, Donaldson SS
      Local Control for Intermediate-Risk Rhabdomyosarcoma: Results From D9803 According to Histology, Group, Site, and Size: A Report From the Children's Oncology Group.
      26581144 International journal of radiation oncology, biology, physics , 2015 Dec. 1 : 93(5)1071-6 PMCID: PMC5147527
    • Oberlin O, Rey A, Brown KL, Bisogno G, Koscielniak E, Stevens MC, Hawkins DS, Meyer WH, La TH, Carli M, Anderson JR
      Prognostic Factors for Outcome in Localized Extremity Rhabdomyosarcoma. Pooled Analysis from Four International Cooperative Groups.
      26257045 Pediatric blood and cancer , 2015 Dec. : 62(12)2125-31 PMCID: PMC5002346
    • Hingorani P, Missiaglia E, Shipley J, Anderson JR, Triche TJ, Delorenzi M, Gastier-Foster J, Wing M, Hawkins DS, Skapek SX
      Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group.
      26473193 Clinical cancer research : an official journal of the American Association for Cancer Research , 2015 Oct. 15 : 21(20)4733-9 PMCID: PMC4610152
    • Rudzinski ER, Anderson JR, Hawkins DS, Skapek SX, Parham DM, Teot LA
      The World Health Organization Classification of Skeletal Muscle Tumors in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group.
      25989287 Archives of pathology and laboratory medicine , 2015 Oct. : 139(10)1281-7 PMCID: PMC4651658
    • Gaspar N, Hawkins DS, Dirksen U, Lewis IJ, Ferrari S, Le Deley MC, Kovar H, Grimer R, Whelan J, Claude L, Delattre O, Paulussen M, Picci P, Sundby Hall K, van den Berg H, Ladenstein R, Michon J, Hjorth L, Judson I, Luksch R, Bernstein ML, Marec-Bérard P, Brennan B, Craft AW, Womer RB, Juergens H, Oberlin O
      Ewing Sarcoma: Current Management and Future Approaches Through Collaboration.
      26304893 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2015 Sept. 20 : 33(27)3036-46
    • Sargar K, Kao SC, Spunt SL, Hawkins DS, Parham DM, Coffin C, McCarville MB
      MRI and CT of Low-Grade Fibromyxoid Sarcoma in Children: A Report From Children's Oncology Group Study ARST0332.
      26204295 AJR. American journal of roentgenology , 2015 Aug. : 205(2)414-20 PMCID: PMC4570741
    • Bielack SS, Smeland S, Whelan JS, Marina N, Jovic G, Hook JM, Krailo MD, Gebhardt M, Pápai Z, Meyer J, Nadel H, Randall RL, Deffenbaugh C, Nagarajan R, Brennan B, Letson GD, Teot LA, Goorin A, Baumhoer D, Kager L, Werner M, Lau CC, Sundby Hall K, Gelderblom H, Meyers P, Gorlick R, Windhager R, Helmke K, Eriksson M, Hoogerbrugge PM, Schomberg P, Tunn PU, Kühne T, Jürgens H, van den Berg H, Böhling T, Picton S, Renard M, Reichardt P, Gerss J, Butterfass-Bahloul T, Morris C, Hogendoorn PC, Seddon B, Calaminus G, Michelagnoli M, Dhooge C, Sydes MR, Bernstein M, EURAMOS-1 investigators.
      Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial.
      26033801 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2015 July 10 : 33(20)2279-87 PMCID: PMC4486345
    • Rodeberg DA, Wharam MD, Lyden ER, Stoner JA, Brown K, Wolden SL, Paidas CN, Donaldson SS, Hawkins DS, Spunt SL, Arndt CA
      Delayed primary excision with subsequent modification of radiotherapy dose for intermediate-risk rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
      25418440 International journal of cancer , 2015 July 1 : 137(1)204-11 PMCID: PMC4474372
    • Lupo PJ, Danysh HE, Plon SE, Curtin K, Malkin D, Hettmer S, Hawkins DS, Skapek SX, Spector LG, Papworth K, Melin B, Erhardt EB, Grufferman S, Schiffman JD
      Family history of cancer and childhood rhabdomyosarcoma: a report from the Children's Oncology Group and the Utah Population Database.
      25809884 Cancer medicine , 2015 May : 4(5)781-90 PMCID: PMC4430270
    • Chen L, Shern JF, Wei JS, Yohe ME, Song YK, Hurd L, Liao H, Catchpoole D, Skapek SX, Barr FG, Hawkins DS, Khan J
      Clonality and evolutionary history of rhabdomyosarcoma.
      25768946 PLoS genetics , 2015 Mar. : 11(3)e1005075 PMCID: PMC4358975
    • Gensheimer MF, Hawkins DS, Ermoian RP, Trister AD
      Assessing the scale of tumor heterogeneity by complete hierarchical segmentation of MRI.
      25575341 Physics in medicine and biology , 2015 Feb. 7 : 60(3)977-93
    • Poon VI, Roth M, Piperdi S, Geller D, Gill J, Rudzinski ER, Hawkins DS, Gorlick R
      Ganglioside GD2 expression is maintained upon recurrence in patients with osteosarcoma.
      25642322 Clinical sarcoma research , 2015 : 5(1)4 PMCID: PMC4311500
    • Walterhouse DO, Pappo AS, Meza JL, Breneman JC, Hayes-Jordan AA, Parham DM, Cripe TP, Anderson JR, Meyer WH, Hawkins DS
      Shorter-duration therapy using vincristine, dactinomycin, and lower-dose cyclophosphamide with or without radiotherapy for patients with newly diagnosed low-risk rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
      25267746 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2014 Nov. 1 : 32(31)3547-52 PMCID: PMC4209105
    • Lupo PJ, Danysh HE, Skapek SX, Hawkins DS, Spector LG, Zhou R, Okcu MF, Papworth K, Erhardt EB, Grufferman S
      Maternal and birth characteristics and childhood rhabdomyosarcoma: a report from the Children's Oncology Group.
      24831857 Cancer causes and control : CCC , 2014 July : 25(7)905-13 PMCID: PMC4091713
    • Rudzinski ER, Anderson JR, Lyden ER, Bridge JA, Barr FG, Gastier-Foster JM, Bachmeyer K, Skapek SX, Hawkins DS, Teot LA, Parham DM
      Myogenin, AP2, NOS-1, and HMGA2 Are Surrogate Markers of Fusion Status in Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
      24618610 The American journal of surgical pathology , 2014 Mar. 10
    • Rosenberg AR, Anderson JR, Lyden E, Rodeberg DA, Wolden SL, Kao SC, Parham DM, Arndt C, Hawkins DS
      Early response as assessed by anatomic imaging does not predict failure-free survival among patients with Group III rhabdomyosarcoma: a report from the Children's Oncology Group.
      24361229 European journal of cancer (Oxford, England : 1990) , 2014 Mar. : 50(4)816-23 PMCID: PMC3944684
    • Shern JF, Chen L, Chmielecki J, Wei JS, Patidar R, Rosenberg M, Ambrogio L, Auclair D, Wang J, Song YK, Tolman C, Hurd L, Liao H, Zhang S, Bogen D, Brohl AS, Sindiri S, Catchpoole D, Badgett T, Getz G, Mora J, Anderson JR, Skapek SX, Barr FG, Meyerson M, Hawkins DS, Khan J
      Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors.
      24436047 Cancer discovery , 2014 Feb. : 4(2)216-31
    • Hawkins DS, Gupta AA, Rudzinski ER
      What is new in the biology and treatment of pediatric rhabdomyosarcoma?
      24326270 Current opinion in pediatrics , 2014 Feb. : 26(1)50-6 PMCID: PMC4096484
    • Russell H, Swint JM, Lal L, Meza J, Walterhouse D, Hawkins DS, Okcu MF
      Cost minimization analysis of two treatment regimens for low-risk rhabdomyosarcoma in children: A report from the Children's Oncology Group.
      24453105 Pediatric blood & cancer , 2014 Jan. 22
    • Eary JF, Conrad EU, O'Sullivan J, Hawkins DS, Schuetze SM, O'Sullivan F
      Sarcoma mid-therapy [F-18]fluorodeoxyglucose positron emission tomography (FDG PET) and patient outcome.
      24430415 The Journal of bone and joint surgery. American volume , 2014 Jan. 15 : 96(2)152-8 PMCID: PMC3903137
    • Lupo PJ, Zhou R, Skapek SX, Hawkins DS, Spector LG, Scheurer ME, Fatih Okcu M, Melin B, Papworth K, Erhardt EB, Grufferman S
      Allergies, atopy, immune-related factors and childhood rhabdomyosarcoma: a report from the Children's Oncology Group.
      23824786 International journal of cancer. Journal international du cancer , 2014 Jan. 15 : 134(2)431-6 PMCID: PMC3869863
    • Chen X, Stewart E, Shelat AA, Qu C, Bahrami A, Hatley M, Wu G, Bradley C, McEvoy J, Pappo A, Spunt S, Valentine MB, Valentine V, Krafcik F, Lang WH, Wierdl M, Tsurkan L, Tolleman V, Federico SM, Morton C, Lu C, Ding L, Easton J, Rusch M, Nagahawatte P, Wang J, Parker M, Wei L, Hedlund E, Finkelstein D, Edmonson M, Shurtleff S, Boggs K, Mulder H, Yergeau D, Skapek S, Hawkins DS, Ramirez N, Potter PM, Sandoval JA, Davidoff AM, Mardis ER, Wilson RK, Zhang J, Downing JR, Dyer MA, St. Jude Childrens Research HospitalWashington University Pediatric Cancer Genome Project
      Targeting oxidative stress in embryonal rhabdomyosarcoma.
      24332040 Cancer cell , 2013 Dec. 9 : 24(6)710-24 PMCID: PMC3904731
    • Spalding AC, Hawkins DS, Donaldson SS, Anderson JR, Lyden E, Laurie F, Wolden SL, Arndt CA, Michalski JM
      The effect of radiation timing on patients with high-risk features of parameningeal rhabdomyosarcoma: an analysis of IRS-IV and D9803.
      24074925 International journal of radiation oncology, biology, physics , 2013 Nov. 1 : 87(3)512-6
    • Wilson RA, Teng L, Bachmeyer KM, Bissonnette ML, Husain AN, Parham DM, Triche TJ, Wing MR, Gastier-Foster JM, Barr FG, Hawkins DS, Anderson JR, Skapek SX, Volchenboum SL
      A novel algorithm for simplification of complex gene classifiers in cancer.
      23913937 Cancer research , 2013 Sept. 15 : 73(18)5625-32
    • Weiss AR, Lyden ER, Anderson JR, Hawkins DS, Spunt SL, Walterhouse DO, Wolden SL, Parham DM, Rodeberg DA, Kao SC, Womer RB
      Histologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
      23940218 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2013 Sept. 10 : 31(26)3226-32 PMCID: PMC3757291
    • Skapek SX, Anderson J, Barr FG, Bridge JA, Gastier-Foster JM, Parham DM, Rudzinski ER, Triche T, Hawkins DS
      PAX-FOXO1 fusion status drives unfavorable outcome for children with rhabdomyosarcoma: a children's oncology group report.
      23526739 Pediatric blood & cancer , 2013 Sept. : 60(9)1411-7
    • Lupo PJ, Zhou R, Skapek SX, Hawkins DS, Spector LG, Scheurer ME, Fatih Okcu M, Melin B, Papworth K, Erhardt EB, Grufferman S
      Allergies, atopy, immune-related factors and childhood rhabdomyosarcoma: A report from the children's oncology group.
      23824786 International journal of cancer. Journal international du cancer , 2013 July 3
    • Skapek SX, Anderson JR, Hill DA, Henry D, Spunt SL, Meyer W, Kao S, Hoffer FA, Grier HE, Hawkins DS, Raney RB
      Safety and efficacy of high-dose tamoxifen and sulindac for desmoid tumor in children: results of a Children's Oncology Group (COG) phase II study.
      23281268 Pediatric blood & cancer , 2013 July : 60(7)1108-12
    • Rudzinski ER, Teot LA, Anderson JR, Moore J, Bridge JA, Barr FG, Gastier-Foster JM, Skapek SX, Hawkins DS, Parham DM
      Dense pattern of embryonal rhabdomyosarcoma, a lesion easily confused with alveolar rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.
      23765537 American journal of clinical pathology , 2013 July : 140(1)82-90
    • Newman EN, Jones RL, Hawkins DS
      An evaluation of [F-18]-fluorodeoxy-D-glucose positron emission tomography, bone scan, and bone marrow aspiration/biopsy as staging investigations in Ewing sarcoma.
      23192939 Pediatric blood & cancer , 2013 July : 60(7)1113-7
    • Skapek SX, Anderson JR, Hill DA, Henry D, Spunt SL, Meyer W, Kao S, Hoffer FA, Grier HE, Hawkins DS, Raney RB
      Safety and efficacy of high-dose tamoxifen and sulindac for desmoid tumor in children: results of a Children's Oncology Group (COG) phase II study.
      23281268 Pediatric blood & cancer , 2013 July : 60(7)1108-12
    • Hawkins DS, Spunt SL, Skapek SX, COG Soft Tissue Sarcoma Committee
      Children's Oncology Group's 2013 blueprint for research: Soft tissue sarcomas.
      23255356 Pediatric blood & cancer , 2013 June : 60(6)1001-8 PMCID: PMC3777409
    • Raney B, Huh W, Hawkins D, Hayes-Jordan A, Million L, Rodeberg D, Teot L, Anderson J, Soft Tissue Sarcoma Committee of the Children's Oncology Group, Arcadia, CA
      Outcome of patients with localized orbital sarcoma who relapsed following treatment on Intergroup Rhabdomyosarcoma Study Group (IRSG) Protocols-III and -IV, 1984-1997: a report from the Children's Oncology Group.
      22961750 Pediatric blood & cancer , 2013 Mar. : 60(3)371-6
    • Gardner RA, Thomson B, Hawkins DS
      Substitution with doxorubicin for daunorubicin during induction for high risk pediatric acute lymphoblastic leukemia results in increased toxicity.
      23015453 Pediatric blood & cancer , 2013 Feb. : 60(2)338-9
    • MacQuarrie KL, Yao Z, Fong AP, Diede SJ, Rudzinski ER, Hawkins DS, Tapscott SJ
      Comparison of genome-wide binding of MyoD in normal human myogenic cells and rhabdomyosarcomas identifies regional and local suppression of promyogenic transcription factors.
      23230269 Molecular and cellular biology , 2013 Feb. : 33(4)773-84 PMCID: PMC3571334
    • Soundararajan A, Abraham J, Nelon LD, Prajapati SI, Zarzabal LA, Michalek JE, McHardy SF, Hawkins DS, Malempati S, Keller C
      18F-FDG microPET imaging detects early transient response to an IGF1R inhibitor in genetically engineered rhabdomyosarcoma models.
      22238194 Pediatric blood & cancer , 2012 Sept. : 59(3)485-92
    • Malempati S, Hawkins DS
      Rhabdomyosarcoma: review of the Children's Oncology Group (COG) Soft-Tissue Sarcoma Committee experience and rationale for current COG studies.
      22378628 Pediatric blood & cancer , 2012 July 15 : 59(1)5-10
    • Rosenberg AR, Skapek SX, Hawkins DS
      The inconvenience of convenience cohorts: rhabdomyosarcoma and the PAX-FOXO1 biomarker.
      22564868 Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology , 2012 July : 21(7)1012-8 PMCID: PMC3392538
    • Spunt SL, Vargas SO, Coffin CM, Skapek SX, Parham DM, Darling J, Hawkins DS, Keller C
      The clinical, research, and social value of autopsy after any cancer death: a perspective from the Children's Oncology Group Soft Tissue Sarcoma Committee.
      22006470 Cancer , 2012 June 15 : 118(12)3002-9 PMCID: PMC3274663
    • Breneman J, Meza J, Donaldson SS, Raney RB, Wolden S, Michalski J, Laurie F, Rodeberg DA, Meyer W, Walterhouse D, Hawkins DS
      Local control with reduced-dose radiotherapy for low-risk rhabdomyosarcoma: a report from the Children's Oncology Group D9602 study.
      22104356 International journal of radiation oncology, biology, physics , 2012 June 1 : 83(2)720-6 PMCID: PMC3305826
    • Gupta AA, Anderson JR, Pappo AS, Spunt SL, Dasgupta R, Indelicato DJ, Hawkins DS
      Patterns of chemotherapy-induced toxicities in younger children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee.
      21761400 Cancer , 2012 Feb. 15 : 118(4)1130-7
    • Raccor BS, Claessens AJ, Dinh JC, Park JR, Hawkins DS, Thomas SS, Makar KW, McCune JS, Totah RA
      Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo.
      21976622 Drug metabolism and disposition: the biological fate of chemicals , 2012 Jan. : 40(1)54-63 PMCID: PMC3250049
    • Hingorani P, Seidel K, Krailo M, Mascarenhas L, Meyers P, Marina N, Conrad EU, Hawkins DS
      Body mass index (BMI) at diagnosis is associated with surgical wound complications in patients with localized osteosarcoma: a report from the Children's Oncology Group.
      21480474 Pediatric blood & cancer , 2011 Dec. 1 : 57(6)939-42 PMCID: PMC3135763
    • Stephenson J, Gow KW, Meehan J, Hawkins DS, Avansino J
      Ewing sarcoma/primitive neuroectodermal tumor arising from the adrenal gland in an adolescent.
      21681923 Pediatric blood & cancer , 2011 Oct. : 57(4)691-2
    • Hawkins DS
      Sarcomas gone bad: what to do about recurrent Ewing sarcoma.
      21681926 Pediatric blood & cancer , 2011 Oct. : 57(4)535-6
    • Malempati S, Rodeberg DA, Donaldson SS, Lyden ER, Anderson JR, Hawkins DS, Arndt CA
      Rhabdomyosarcoma in infants younger than 1 year: a report from the Children's Oncology Group.
      21264837 Cancer , 2011 Aug. 1 : 117(15)3493-501 PMCID: PMC3140625
    • Walterhouse DO, Meza JL, Breneman JC, Donaldson SS, Hayes-Jordan A, Pappo AS, Arndt C, Raney RB, Meyer WH, Hawkins DS
      Local control and outcome in children with localized vaginal rhabdomyosarcoma: a report from the Soft Tissue Sarcoma committee of the Children's Oncology Group.
      21298768 Pediatric blood & cancer , 2011 July 15 : 57(1)76-83 PMCID: PMC3459820
    • Foster JH, Hawkins DS, Loken MR, Wells DA, Thomson B
      Minimal residual disease detected prior to hematopoietic cell transplantation.
      21370437 Pediatric blood & cancer , 2011 July 15 : 57(1)163-5
    • La TH, Wolden SL, Rodeberg DA, Hawkins DS, Brown KL, Anderson JR, Donaldson SS
      Regional nodal involvement and patterns of spread along in-transit pathways in children with rhabdomyosarcoma of the extremity: a report from the Children's Oncology Group.
      20542386 International journal of radiation oncology, biology, physics , 2011 July 15 : 80(4)1151-7 PMCID: PMC3116031
    • Million L, Anderson J, Breneman J, Hawkins DS, Laurie F, Michalski J, Rodeberg D, Wharam M, Wolden S, Donaldson SS, Soft Tissue Sarcoma Committee of the Children's Oncology Group
      Influence of noncompliance with radiation therapy protocol guidelines and operative bed recurrences for children with rhabdomyosarcoma and microscopic residual disease: a report from the Children's Oncology Group.
      20646841 International journal of radiation oncology, biology, physics , 2011 June 1 : 80(2)333-8
    • Rodeberg DA, Stoner JA, Garcia-Henriquez N, Randall RL, Spunt SL, Arndt CA, Kao S, Paidas CN, Million L, Hawkins DS
      Tumor volume and patient weight as predictors of outcome in children with intermediate risk rhabdomyosarcoma: a report from the Children's Oncology Group.
      24048802 Cancer , 2011 June 1 : 117(11)2541-50 PMCID: PMC3117103
    • La TH, Wolden SL, Su Z, Linardic C, Randall RL, Hawkins DS, Donaldson SS
      Local therapy for rhabdomyosarcoma of the hands and feet: is amputation necessary? A report from the Children's Oncology Group.
      20646853 International journal of radiation oncology, biology, physics , 2011 May 1 : 80(1)206-12 PMCID: PMC3075377
    • Rodeberg DA, Garcia-Henriquez N, Lyden ER, Davicioni E, Parham DM, Skapek SX, Hayes-Jordan AA, Donaldson SS, Brown KL, Triche TJ, Meyer WH, Hawkins DS
      Prognostic significance and tumor biology of regional lymph node disease in patients with rhabdomyosarcoma: a report from the Children's Oncology Group.
      21357792 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2011 Apr, 1 : 29(10)1304-11 PMCID: PMC3083998
    • Eary JF, Hawkins DS, Rodler ET, Conrad EU 3rd
      (18)F-FDG PET in sarcoma treatment response imaging.
      23133794 American journal of nuclear medicine and molecular imaging , 2011 : 1(1)47-53 PMCID: PMC3477719
    • Rodeberg DA, Stoner JA, Garcia-Henriquez N, Randall RL, Spunt SL, Arndt CA, Kao S, Paidas CN, Million L, Hawkins DS
      Tumor volume and patient weight as predictors of outcome in children with intermediate risk rhabdomyosarcoma: a report from the children's oncology group.
      21157950 Cancer , 2010 Dec. 14
    • Mascarenhas L, Lyden ER, Breitfeld PP, Walterhouse DO, Donaldson SS, Paidas CN, Parham DM, Anderson JR, Meyer WH, Hawkins DS
      Randomized phase II window trial of two schedules of irinotecan with vincristine in patients with first relapse or progression of rhabdomyosarcoma: a report from the Children's Oncology Group.
      20837952 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2010 Oct. 20 : 28(30)4658-63 PMCID: PMC2974343
    • Anderson JR, Barr FG, Hawkins DS, Parham DM, Skapek SX, Triche TJ
      Fusion-negative alveolar rhabdomyosarcoma: modification of risk stratification is premature.
      20697086 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2010 Oct. 10 : 28(29)e587-8; author reply e589-90
    • Minn AY, Lyden ER, Anderson JR, Million L, Arndt CA, Brown K, Hawkins DS, Donaldson SS
      Early treatment failure in intermediate-risk rhabdomyosarcoma: results from IRS-IV and D9803--a report from the Children's Oncology Group.
      20713850 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2010 Sept. 20 : 28(27)4228-32 PMCID: PMC2953975
    • Arndt CA, Koshkina NV, Inwards CY, Hawkins DS, Krailo MD, Villaluna D, Anderson PM, Goorin AM, Blakely ML, Bernstein M, Bell SA, Ray K, Grendahl DC, Marina N, Kleinerman ES
      Inhaled granulocyte-macrophage colony stimulating factor for first pulmonary recurrence of osteosarcoma: effects on disease-free survival and immunomodulation. a report from the Children's Oncology Group.
      20576718 Clinical cancer research : an official journal of the American Association for Cancer Research , 2010 Aug. 1 : 16(15)4024-30 PMCID: PMC2989183
    • Koschmann C, Thomson B, Hawkins DS
      No evidence of a trial effect in newly diagnosed pediatric acute lymphoblastic leukemia.
      20194252 Archives of pediatrics & adolescent medicine , 2010 Mar. : 214-7
    • Schmale GA, Hawkins DS, Rutledge J, Conrad EU
      Malignant progression in two children with multiple osteochondromas.
      20467466 Sarcoma , 2010 : 2010417105 PMCID: PMC2866243
    • Fox E, Widemann BC, Hawkins DS, Jayaprakash N, Dagher R, Aikin AA, Bernstein D, Long L, Mackall C, Helman L, Steinberg SM, Balis FM
      Randomized trial and pharmacokinetic study of pegfilgrastim versus filgrastim after dose-intensive chemotherapy in young adults and children with sarcomas.
      19920107 Clinical cancer research : an official journal of the American Association for Cancer Research , 2009 Dec. 1 : 15(23)7361-7 PMCID: PMC2787766
    • Arndt CA, Stoner JA, Hawkins DS, Rodeberg DA, Hayes-Jordan AA, Paidas CN, Parham DM, Teot LA, Wharam MD, Breneman JC, Donaldson SS, Anderson JR, Meyer WH
      Vincristine, actinomycin, and cyclophosphamide compared with vincristine, actinomycin, and cyclophosphamide alternating with vincristine, topotecan, and cyclophosphamide for intermediate-risk rhabdomyosarcoma: children's oncology group study D9803.
      19770373 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2009 Nov. 1 : 27(31)5182-8 PMCID: PMC2773476
    • Borinstein SC, Pollard J, Winter L, Hawkins DS
      Pegfilgrastim for prevention of chemotherapy-associated neutropenia in pediatric patients with solid tumors.
      19484756 Pediatric blood & cancer , 2009 Sept. : 53(3)375-8
    • Rodeberg DA, Stoner JA, Hayes-Jordan A, Kao SC, Wolden SL, Qualman SJ, Meyer WH, Hawkins DS
      Prognostic significance of tumor response at the end of therapy in group III rhabdomyosarcoma: a report from the children's oncology group.
      19470937 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2009 Aug. 1 : 27(22)3705-11 PMCID: PMC3020959
    • Hawkins DS, Conrad EU 3rd, Butrynski JE, Schuetze SM, Eary JF
      [F-18]-fluorodeoxy-D-glucose-positron emission tomography response is associated with outcome for extremity osteosarcoma in children and young adults.
      19517457 Cancer , 2009 Aug. 1 : 115(15)3519-25 PMCID: PMC2716419
    • Rodeberg DA, Stoner JA, Hayes-Jordan A, Kao SC, Wolden SL, Qualman SJ, Meyer WH, Hawkins DS
      Prognostic significance of tumor response at the end of therapy in group III rhabdomyosarcoma: a report from the children's oncology group.
      19470937 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2009 Aug. 1 : 3705-11
    • Imran H, Enders F, Krailo M, Sim F, Okuno S, Hawkins D, Neglia J, Randall RL, Womer R, Mascarenhas L, Arndt CA
      Effect of time to resumption of chemotherapy after definitive surgery on prognosis for non-metastatic osteosarcoma.
      19255220 The Journal of bone and joint surgery. American volume , 2009 Mar. 1 : 91(3)604-12 PMCID: PMC2701597
    • Cengiz P, Zemlan F, Ellenbogen R, Hawkins D, Zimmerman JJ
      Cerebrospinal fluid cleaved-tau protein and 9-hydroxyoctadecadienoic acid concentrations in pediatric patients with hydrocephalus.
      18679140 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2008 Sept. : 9(5)524-9
    • Rodriguez NI, Hoots WK, Koshkina NV, Morales-Arias JA, Arndt CA, Inwards CY, Hawkins DS, Munsell MF, Kleinerman ES
      COX-2 expression correlates with survival in patients with osteosarcoma lung metastases.
      18797196 Journal of pediatric hematology/oncology , 2008 July : 30(7)507-12 PMCID: PMC2771732
    • Wirojanan J, Kraff J, Hawkins DS, Laird C, Gane LW, Angkustsiri K, Tassone F, Hagerman RJ
      Two boys with fragile x syndrome and hepatic tumors.
      18376289 Journal of pediatric hematology/oncology , 2008 Mar. : 30(3)239-41
    • Arndt CA, Hawkins DS, Meyer WH, Sencer SF, Neglia JP, Anderson JR
      Comparison of results of a pilot study of alternating vincristine/doxorubicin/cyclophosphamide and etoposide/ifosfamide with IRS-IV in intermediate risk rhabdomyosarcoma: a report from the Children's Oncology Group.
      17091486 Pediatric blood & cancer , 2008 Jan. : 50(1)33-6
    • Borinstein SC, Xu M, Hawkins DS
      Methemoglobinemia and hemolytic anemia caused by rasburicase administration in a newly diagnosed child with Burkitt lymphoma/leukemia.
      17387701 Pediatric blood & cancer , 2008 Jan. : 50(1)189
    • Douglas JG, Arndt CA, Hawkins DS
      Delayed radiotherapy following dose intensive chemotherapy for parameningeal rhabdomyosarcoma (PM-RMS) of childhood.
      17368885 European journal of cancer (Oxford, England : 1990) , 2007 Apr, : 43(6)1045-50
    • Greene S, Hawkins DS, Rutledge JC, Tsuchiya KD, Douglas J, Ellenbogen RG, Avellino AM
      Pediatric intradural extramedullary synovial sarcoma: case report.
      17277671 Neurosurgery , 2006 Dec. : E1339; discussion E1339
    • Hawkins DS, Bradfield S, Whitlock JA, Krailo M, Franklin J, Blaney SM, Adamson PC, Reaman G
      Topotecan by 21-day continuous infusion in children with relapsed or refractory solid tumors: a Children's Oncology Group study.
      16435380 Pediatric blood & cancer , 2006 Nov. : 47(6)790-4
    • Taylor JA, Winter L, Geyer LJ, Hawkins DS
      Oral outpatient chemotherapy medication errors in children with acute lymphoblastic leukemia.
      16909415 Cancer , 2006 Sept. 15 : 107(6)1400-6
    • Morgan HD, Cizik AM, Leopold SS, Hawkins DS, Conrad EU 3rd
      Survival of tumor megaprostheses replacements about the knee.
      16906094 Clinical orthopaedics and related research , 2006 Sept. : 45039-45
    • Hawkins DS, Schuetze SM, Butrynski JE, Rajendran JG, Vernon CB, Conrad EU 3rd, Eary JF
      [18F]Fluorodeoxyglucose positron emission tomography predicts outcome for Ewing sarcoma family of tumors.
      16314643 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2005 Dec. 1 : 23(34)8828-34
    • Cole PD, Drachtman RA, Smith AK, Cate S, Larson RA, Hawkins DS, Holcenberg J, Kelly K, Kamen BA
      Phase II trial of oral aminopterin for adults and children with refractory acute leukemia.
      16299240 Clinical cancer research : an official journal of the American Association for Cancer Research , 2005 Nov. 15 : 11(22)8089-96 PMCID: PMC2906753
    • Gordon N, Arndt CA, Hawkins DS, Doherty DK, Inwards CY, Munsell MF, Stewart J, Koshkina NV, Kleinerman ES
      Fas expression in lung metastasis from osteosarcoma patients.
      16282894 Journal of pediatric hematology/oncology , 2005 Nov. : 27(11)611-5
    • Spiller SE, Hawkins DS, Finn LS, Sze RW, Sybert V
      Metastatic malignant melanoma presenting as pancytopenia in a three-year-old boy.
      15800910 Pediatric blood & cancer , 2005 July : 45(1)60-3
    • Barker LM, Pendergrass TW, Sanders JE, Hawkins DS
      Survival after recurrence of Ewing's sarcoma family of tumors.
      15781881 Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2005 July 1 : 23(19)4354-62
    • Schuetze SM, Rubin BP, Vernon C, Hawkins DS, Bruckner JD, Conrad EU 3rd, Eary JF
      Use of positron emission tomography in localized extremity soft tissue sarcoma treated with neoadjuvant chemotherapy.
      15578712 Cancer , 2005 Jan. 15 : 103(2)339-48
    • Hawkins DS
      Transatlantic collaboration in pediatric oncology: now is the time.
      15591895 Journal of pediatric hematology/oncology , 2004 Dec. : 26(12)783-4
    • Thomson B, Park JR, Felgenhauer J, Meshinchi S, Holcenberg J, Geyer JR, Avramis V, Douglas JG, Loken MR, Hawkins DS
      Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse.
      15382275 Pediatric blood & cancer , 2004 Oct. : 571-9
    • Hawkins DS, Park JR, Thomson BG, Felgenhauer JL, Holcenberg JS, Panosyan EH, Avramis VI
      Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia.
      15328169 Clinical cancer research : an official journal of the American Association for Cancer Research , 2004 Aug. 15 : 5335-41
    • McCune JS, Friedman DL, Schuetze S, Blough D, Magbulos M, Hawkins DS
      Influence of age upon Ifosfamide-induced nephrotoxicity.
      15049014 Pediatric blood & cancer , 2004 May : 42(5)427-32
    • Bradfield SM, Douglas JG, Hawkins DS, Sanders JE, Park JR
      Fractionated low-dose radiotherapy after myeloablative stem cell transplantation for local control in patients with high-risk neuroblastoma.
      15022296 Cancer , 2004 Mar. 15 : 100(6)1268-75
    • Finn LS, Hawkins DS, Rutledge JC, Patterson K
      Evaluation of early marrow response in childhood aneuploid acute lymphoblastic leukemia: flow cytometric DNA analysis versus standard morphology.
      15255034 Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2004 Jan. : 7(1)39-47
    • Hawkins DS, Arndt CA
      Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy.
      14635080 Cancer , 2003 Dec. 1 : 98(11)2447-56
    • Smith SC, Lindsley SK, Felgenhauer J, Hawkins DS, Douglas JG
      Intensive induction chemotherapy and delayed irradiation in the management of parameningeal rhabdomyosarcoma.
      14528099 Journal of pediatric hematology/oncology , 2003 Oct. : 25(10)774-9
    • Wright JA, Bradfield SM, Park JR, Hawkins DS
      Prolonged survival after invasive aspergillosis: a single-institution review of 11 cases.
      12679641 Journal of pediatric hematology/oncology , 2003 Apr, : 25(4)286-91
    • Wright JA, Bradfield SM, Park JR, Hawkins DS
      Prolonged survival after invasive aspergillosis: a single-institution review of 11 cases.
      12679641 Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology , 2003 Apr, : 286-91
    • Park JR, Coughlin J, Hawkins D, Friedman DL, Burns JL, Pendergrass T
      Ciprofloxacin and amoxicillin as continuation treatment of febrile neutropenia in pediatric cancer patients.
      12461792 Medical and pediatric oncology , 2003 Feb. : 40(2)93-8
    • Hawkins DS, Felgenhauer J, Park J, Kreissman S, Thomson B, Douglas J, Rowley SD, Gooley T, Sanders JE, Pendergrass TW
      Peripheral blood stem cell support reduces the toxicity of intensive chemotherapy for children and adolescents with metastatic sarcomas.
      12216105 Cancer , 2002 Sept. 15 : 1354-65
    • Mansky PJ, Liewehr DJ, Steinberg SM, Chrousos GP, Avila NA, Long L, Bernstein D, Mackall CL, Hawkins DS, Helman LJ
      Treatment of metastatic osteosarcoma with the somatostatin analog OncoLar: significant reduction of insulin-like growth factor-1 serum levels.
      12218590 Journal of pediatric hematology/oncology , 2002 Aug. : 24(6)440-6
    • Hawkins DS, Rajendran JG, Conrad EU 3rd, Bruckner JD, Eary JF
      Evaluation of chemotherapy response in pediatric bone sarcomas by [F-18]-fluorodeoxy-D-glucose positron emission tomography.
      12115361 Cancer , 2002 June 15 : 94(12)3277-84

  • Presentations Title Event Location Date
    Progress in the treatment of rhabdomyosarcoma: results of the North American strategy European Cancer Congress Amsterdam, Netherlands Sept. 29, 2013
    Childrens Oncology Group update on soft tissue sarcoma clinical trials European Paediatric Soft Tissue Sarcoma Meeting Paris, France March 22, 2013
    COG approach to identification and introduction of new/targeted therapies in RMS/STS European Paediatric Soft Tissue Sarcoma Meeting Paris, France, March 22, 2013
    Rhabdomyosarcoma: How many and how to treat Texas Childrens Cancer Center Houston, TX Feb. 14, 2013
    What children have taught me about rhabdomyosarcoma Pediatric Grand Rounds, Childrens Hospital at Montefiore Bronx, NY Jan. 30, 2013
    From Seattle to Sydney: lessons from selected pediatric sarcoma cases Pediatric Oncology Conference Sydney, Australia Oct. 8, 2012
    Childrens Oncology Group update on soft tissue sarcoma clinical trials International Symposium on the Biology and Treatment of the Pediatric Soft Tissue Sarcomas Padova, Italy Dec. 6, 2011
    Risk stratification and treatment approaches in rhabdomyosarcoma: a comparison of Europe and North America Pediatric Oncology Group of Ontario Nov. 19, 2010
  • Grant Title Grantor Amount Award Date
    Children’s Oncology Group trial AEWS0531 NIH $11,956.00 March 1, 2009
    Children’s Oncology Group trial AEWS0331 NIH $11,956.00 March 1, 2009
    Children’s Oncology Group Soft Tissue Sarcoma Committee Chair NIH $23.913.00 March 1, 2009
    Children’s Oncology Group- cooperative group trial, Institutional Principal NIH $57,390.00 March 1, 2009

Overview

Board Certification(s)

Pediatric Hematology-Oncology

Medical/Professional School

Harvard Medical School, Boston

Residency

Pediatrics, University of Washington, Seattle

Clinical Interests

Sarcomas, New therapy

Research Description

My clinical research is particularly focused in the treatment of pediatric sarcomas. I am the Children's Oncology Group (COG) chair of the Soft Tissue Sarcoma Committee, which designs and conducts all national studies in pediatric soft tissue sarcomas, including rhabdomyosarcoma. I have been the COG chair of two clinical trials, one for Ewing sarcoma and another for rhabdomyosarcoma, and the vice chair of three other COG clinical trials. I have worked collaboratively on host and tumor genomic factors that predict toxicity and outcome in pediatric sarcomas.

Research Focus Area

Cancer