Heart and Blood Conditions
Langerhans Cell Histiocytosis Treatment
- For appointments, call 206-987-2106.
- How to schedule.
- Need a second opinion? Call 206-987-2106.
If this is a medical emergency, call 911.
- Urgent consultations (providers only): call 206-987-7777 or toll free 877-985-4637.
- If you are a provider, fax a New Appointment Request Form (PDF) (DOC) to 206-985-3121 or 866-985-3121 (toll-free).
- No pre-referral workup is required for most conditions. If you have already done a work-up, please fax this information as well as relevant clinic notes and the NARF to 206-985-3121 or 866-985-3121 (toll-free).
- View our complete Cancer and Blood Disorders Center Referral Information (PDF).
Treatment for Langerhans cell histiocytosis depends on how many parts of the body are affected and which parts. Here are the main treatments that doctors use. All of these are offered through Seattle Children’s.
Treatment Options for Langerhans Cell Histiocytosis
Doctors may operate to remove the excess Langerhans cells (used mostly for bones).
Steroid medicine may be injected into the places with excess Langerhans cells.
Chemotherapy medicines used to kill cancer cells may also help control Langerhans cells. Doctors give some types of these medicines through an intravenous (IV) line. For skin problems, they may apply medicines right on the skin. The doses are lower than those used for cancer.
Our patients with this disease receive chemotherapy at our main campus in Seattle — most often in a clinic (as outpatients), but sometimes during a stay in the hospital (as inpatients).
This treatment can help control cells that are damaging bone and making it weak. The doses are lower than those used for cancer. Our patients receive radiation therapy through our partner, UW Medicine.
Learn more about Seattle Children’s Radiation Therapy Service.
New Treatments for Langerhans Cell Histiocytosis
Seattle Children’s is working with the Histiocyte Society to develop better treatments for Langerhans. Your child’s doctor will talk with you in detail about any new treatment that might be a match for your child. Then you can decide whether you want to try that option.
Read more about research and clinical trials at Seattle Children’s.