Immunology Diagnostic Laboratory: A Jeffrey Modell Foundation Diagnostic Center

List of Flow Cytometry and Functional Tests Offered

Note: The following tests are offered as research use only.

Protein Expression

BTK
CD40
CD40 ligand (includes functional analysis of CD40 biding to CD40)
DOCK8
FOXP3(includes analysis of CD25 expression)
WASP

Functional Analysis

CD40 binding to CD40 ligand (done routinely with CD40L protein expression)
HIES Screen (includes analysis of STAT3 phosphorylation in response to cytokines and Th17 cell percentage)
IL-10 Receptor (analysis of STAT3 phosphorylation in response to IL-10)
STAT1-GOF Screen (analysis of STAT1 phosphorylation/hyper-phosphorylation in response to cytokine stimulation)
X-SCID Screen (analysis of STAT5B phosphorylation in response to IL-2 and IL-7 screening test for common gamma chain, JAK3 and IL-7 receptor deficiency)

Immunophenotyping

Regulatory T-cell immunophenotyping (evaluation of FOXP3+ regulatory T cells)

Bacteriophage Immunization

For information or to arrange bacteriophage immunization to evaluate immune responses, call 206-987-7435.

Seattle Children’s complies with applicable federal and other civil rights laws and does not discriminate, exclude people or treat them differently based on race, color, religion (creed), sex, gender identity or expression, sexual orientation, national origin (ancestry), age, disability, or any other status protected by applicable federal, state or local law. Financial assistance for medically necessary services is based on family income and hospital resources and is provided to children under age 21 whose primary residence is in Washington, Alaska, Montana or Idaho.