Sarah Elisabeth Sherr Leary, MD


On staff since August 2009

Academic Title: Associate Professor

Research Center: Center for Clinical and Translational Research

"It is a privilege to work with children as part of a multidisciplinary team of clinicians and researchers who are so dedicated to providing the best care for our patients today while at the same time working to find a cure for every child in the future. My favorite days are those when I receive notes and pictures from my former patients who now are living long, healthy lives free of cancer."

  • Sarah Leary, MD, is an attending physician in the Cancer and Blood Disorders Center at Seattle Childrens Hospital and Associate Professor of Pediatrics at the University of Washington School of Medicine. Her clinical and research focus is in the area of pediatric brain tumors.

    Locally, she serves on the Tumor Tissue Subcommittee and the Research Review Committee; Nationally, she is leading several clinical trials to study new medications for children with brain tumors at Seattle Children's Hospital, through the Children's Oncology Group, the Pacific Pediatric Neuro-Oncology Consortium (PNOC)and the Pediatric Brain Tumor Consortium (PBTC). Dr. Leary works with laboratory investigators at the Fred Hutchinson Cancer Research Center and the Seattle Children's Research Institute as well as the Pathology Department at Seattle Children's Hospital to identify novel therapeutic targets and tests. The goal of her clinical and translational research is to improve outcomes for brain tumor patients by developing biologically targeted therapeutics.

    • Amy Selah, WA 09.25.11

      We've been working with Dr. Leary for almost a year. I applaud anyone who is brave enough to go into this career, but particularly Dr. Leary and her unfaultering optimism. From the first moment we met I felt peace that she could and would provide the best medical care for my son. I know that her actions are always performed with the interest of her patients at the forefront. We feel very grateful to have such talent available at our nearest children's hospital.

    • Leisha Petaluma, CA 12.30.10

      Dr. Leary is one of the most compassionate physicians I have ever had the priviledge to know. The entire time my six year old was being treated in Seattle Dr. Leary provided consistent care and support above and beyond what is required.

  • Award Name Award Description Awarded By Award Date
    Alpha Omega Alpha University of Tennessee College of Medicine 2001
    Outstanding Student in Neurology University of Tennessee College of Medicine 2001
    Family Choice Award Nomination 2011 and 2013 The Family Advisory Council invites patients and families to nominate a staff member who demonstrates the qualities of Family Centered Care
  • Other Publications

    • Koschmann C, Bloom K, Upadhyaya S, Geyer JR, Leary SE
      Survival After Relapse of Medulloblastoma.
      26907655 Journal of pediatric hematology/oncology, 2016 Feb. 22
    • Voss SD, Glade-Bender J, Spunt SL, DuBois SG, Widemann BC, Park JR, Leary SE, Nelson MD, Adamson PC, Blaney SM, Weigel B
      Growth plate abnormalities in pediatric cancer patients undergoing phase 1 anti-angiogenic therapy: a report from the Children's Oncology Group Phase I Consortium.
      25257751 Pediatric blood and cancer, 2015 Jan. : 62(1)45-51 PMCID:PMC4237627
    • Leary PJ, Harris Nolley SJ, Ralph DD, Leary SE
      Elevated pulmonary pressure in survivors of pediatric cancer: a physiologic finding, not a specific disease.
      23816966 Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013 Aug. 1 : 31(22)2833-4
    • Leary SE, Wozniak AW, Billups CA, Wu J, McPherson V, Neel MD, Rao BN, Daw NC
      Survival of pediatric patients after relapsed osteosarcoma: the St. Jude Children's Research Hospital experience.
      23625626 Cancer, 2013 July 15 : 119(14)2645-53
    • Yang T, Temkin N, Barber J, Geyer JR, Leary S, Browd S, Ojemann JG, Ellenbogen RG
      Gross total resection correlates with long-term survival in pediatric patients with glioblastoma.
      23017588 World neurosurgery, 2013 March : 79(3-4)537-44
    • Ojemann JG, Hersonskey TY, Abeshaus S, Geyer JR, Saneto RP, Novotny EJ, Kollros P, Leary S, Holmes MD
      Epilepsy surgery after treatment of pediatric malignant brain tumors.
      22835666 Seizure : the journal of the British Epilepsy Association, 2012 Oct. : 21(8)624-30
    • Kelly JP, Leary S, Khanna P, Weiss AH
      Longitudinal measures of visual function, tumor volume, and prediction of visual outcomes after treatment of optic pathway gliomas.
      22364864 Ophthalmology, 2012 June : 119(6)1231-7
    • Leary SE, Olson JM
      The molecular classification of medulloblastoma: driving the next generation clinical trials.
      22189395 Current opinion in pediatrics, 2012 Feb. : 24(1)33-9 PMCID:PMC3348176
    • Pounds S, Gao CL, Johnson RA, Wright KD, Poppleton H, Finkelstein D, Leary SE, Gilbertson RJ
      A procedure to statistically evaluate agreement of differential expression for cross-species genomics.
      21697127 Bioinformatics (Oxford, England), 2011 Aug. 1 : 27(15)2098-103 PMCID:PMC3137228
    • Leary SE, Zhou T, Holmes E, Geyer JR, Miller DC
      Histology predicts a favorable outcome in young children with desmoplastic medulloblastoma: a report from the children's oncology group.
      21246528 Cancer, 2011 July 15 : 117(14)3262-7 PMCID:PMC3119763
    • Johnson RA, Wright KD, Poppleton H, Mohankumar KM, Finkelstein D, Pounds SB, Rand V, Leary SE, White E, Eden C, Hogg T, Northcott P, Mack S, Neale G, Wang YD, Coyle B, Atkinson J, DeWire M, Kranenburg TA, Gillespie Y, Allen JC, Merchant T, Boop FA, Sanford RA, Gajjar A, Ellison DW, Taylor MD, Grundy RG, Gilbertson RJ
      Cross-species genomics matches driver mutations and cell compartments to model ependymoma.
      20639864 Nature, 2010 July 29 : 466(7306)632-6 PMCID:PMC2912966
    • Leary SE, Harrod VL, de Alarcon PA, Reiss UM
      Low-dose systemic thrombolytic therapy for deep vein thrombosis in pediatric patients.
      20118811 Journal of pediatric hematology/oncology, 2010 March : 32(2)97-102 PMCID:PMC3482506


Board Certification(s)

Pediatric Hematology-Oncology

Medical/Professional School

University of Tennessee Health Science Center, Memphis


Pediatrics, Johns Hopkins Hospital, Baltimore


Pediatric Hematology Oncology, St. Jude Children's Research Hospital, Memphis

Clinical Interests

Pediatric brain tumors, novel therapeutics

Research Focus Area

Translational Research, Cancer biology