Klane K. White, MD, MSc

Klane K. White, MD, MSc

Orthopedics, Skeletal Health Program, Spine Program, Fracture Program, Cerebral Palsy Program

On staff since August 2006

Children's Title: Director, Skeletal Health Dysplasia; Medical Director, Orthopaedic Research

Academic Title: Professor of Orthopaedic Surgery

Research Center: Center for Clinical and Translational Research

  • Klane K. White, MD, MSc is a pediatric orthopaedic surgeon and Director of the Skeletal Health and Dysplasia Program at Seattle Children’s Hospital. He is a Professor of Orthopaedic Surgery at the University of Washington and a diplomate of the American Board of Orthopaedic Surgery.

    A graduate of the University of Southern California, Dr. White earned his bachelor and master’s degrees in Biology and Biological Oceanography, respectively.  He received his Doctor of Medicine from the George Washington University in Washington, DC. Dr. White completed his surgical internship and orthopaedic surgery residency at the University of California San Diego, as well as a two-year NIH sponsored fellowship in orthopaedic research. He received advanced fellowship training in pediatric orthopaedics and scoliosis at Texas Scottish Rite Hospital for Children in Dallas, Texas.

    Dr. White is an internationally recognized expert and advocate in the care of mucopolysaccharidosis and skeletal dysplasia. He serves on the Medical Advisory Board of Little People of America and is an executive founding member and current president of the Skeletal Dysplasia Management Consortium. Following three terms on the National MPS Society board of directors, he continues to chair the technical grant review committee, and serves on the Scientific Advisory Board. His professional affiliations include membership in the Pediatric Orthopaedic Society of North America, Scoliosis Research Society, American Academy of Orthopedic Surgeons, American Academy of Pediatrics, American Orthopedic Association and Pediatric Spine Study Group. Distinctions include the combined Pediatric Orthopaedic Society of North America/ European Pediatric Orthopaedic Society Traveling Fellowship, the Scoliosis Research Society Edgar Dawson Traveling Fellowship, and the Pediatric Orthopaedic Society of North America Angela S.M. Kuo Memorial Young Investigator Award.

    In addition to skeletal dysplasia and the mucopolysaccharidoses, Dr. White’s clinical and research interests also include the diagnosis and management of early onset scoliosis (including VEPTR and magnetic growing rods), metabolic bone disease, and complex spine deformity. As a key opinion leader in these fields, he trains residents, fellows, visiting scholars, and is a frequent invited lecturer at national and international conferences, courses, symposia, and patient advocacy meetings. His research is routinely presented at national and international scientific and specialty society congresses, and he is principal investigator in several multicenter research studies for rare disease. Dr. White has authored more than 90 peer-reviewed publications, review articles and book chapters. He is a standing reviewer for the Journal of Pediatric Orthopedics and the Journal of the American Academy of Orthopaedic Surgery. He serves as Associate Editor for Frontiers in Pediatrics – Orthopaedics section, an ad hoc reviewer for multiple other medical journals, including Orphanet Journal of Rare Disease and The Journal of Inherited Metabolic Disease, and as guest editor for Journal of Pediatric Orthopaedics.

    Married to his college sweetheart and the proud father of two daughters, in his spare time Dr. White enjoys playing guitar, gardening, running, and is a die-hard USC Trojan football fan.

    • Shannon Des Moines, WA 07.15.21

      Dr. White is truly an incredible provider that is thoughtful in his approaches. He gives honest feedback in laypeople terms with risks and benefits for what needs to be done. His bedside manner is beyond what any other provider has given in our 19 year journey. I routinely send other families from all over the world to him as he has benefited our daughter greatly. Having been her provider for over 8 years now I trust his professional opinion on what next steps should be on her very complex case. Truly one of the best in the business that knows how to compassionately take care of families not just the patient.

    • Jared Marysville, WA 06.21.16

      Dr. White has been my son's doctor for the past several years and he has provided an excellent level of care. My son had a magnetic growth rod installed in October of 2014 to correct severe scoliosis of the spine. The care before, during, and after the procedure was excellent. Dr. White and his staff were very compassionate and informative throughout the process.

    • Jeff kirkland Wa 04.24.16

      Dr. White saw my son Jeffery after a trampoline accident that broke Jeffery's humorus bone just above the elbow ( level 3 break). Dr. white and his team operated on my son and did an amazing job fixing my sons arm.. thank you to dr. white and children's hospital for great care to our son Jeffery.

    • Tatiana Tacoma, WA 09.09.15

      Dr. White is amazing doctor. He fixed my son foot (tendon surgery)- it was almost crooked and my son had issue in the hip area because of that. Dr. White is great doctor and I would recommend him.

    • Rebecca Snohomish Washington 07.09.12

      i could not ask for more than a wounderful doctor like dr.white. he has been awesome to me and he is the one i turn too with my hip. i had hip dysplasia and had surgery on it a lot. he has been there thick and thin with me and he has helped me with my infection and making sur i am ok and well qnd also comfertable. so thank you dr. white you ARE THE BEST. love rebecca smith

    • Chloe Olympia, WA 10.23.11

      Dr. White is an amazing doctor! He's been my surgeon since 2007 and has helped me with my hip dysplasia. I really couldn't ask for a better doctor! He has a wonderful personality and he puts up with A LOT! Thanks Dr. White!!

  • Award Name Award Description Awarded By Award Date
    Family Choice Award On behalf of the Family Advisory Council and the family who nominated you, thank you for your commitment to family-centered care. You make a difference for patients and their families. Seattle Children's Hospital 2020
    AAOS Achievement Award American Academy of Orthopedic Surgery 2018
    SEATTLE MAGAZINE TOP DOCTOR - 2014 Seattle Magazine 2014
    2012 POSNA Travelling Fellowship Award Pediatric Orthopaedic Society of North America April 2012
    Angela S.M. Kuo Memorial Young Investigator Award Pediatric Orthopaedic Society of North America May 2011
    The Edgar Dawson Travelling Fellowship Scoliosis Research Society Jan. 2009
    Boone Pickens Annual Fellows Award for Excellence in Orthopaedic Research “Ultrasonographic predictors of Pavlik harness failure in Ortolani positive hips” May 2006
  • Presentations Title Event Location Date
    Should we screen all babies with achondroplasia for foramen magnum stenosis with an MRI? No not all babies need a screening MRI International Conference on Children’s Bone Health Salzburg, Austria June 2019
    Perthes Disease 7th POSNA-ASEAN Malaysia Course Penang, Malaysia Jan. 2019
    Transitional Ankle Fractures: How do I decide when to operate POSNA-ASEAN Malaysia Course Penang, Malaysia Jan. 2019
    Proximal Femoral Osteotomy 7th POSNA-ASEAN Malaysia Course Penang, Malaysia Jan. 2019
    Fractures Around the Knee: what is dangerous and why? 7th POSNA-ASEAN Malaysia Course Penang, Malaysia Jan. 2019
    Acute Osteomyelitis and Septic Arthritis 7th POSNA-ASEAN Penang, Malaysia Jan. 2019
    Bone and Joint Disease in MPS 2nd Asia-Pacific Bone Disorders Symposium Melbourne, Australia Nov. 2018
    Case Series: Opportunities to Reduce Diagnostic Delay for Patients with MPS IVA and VI”, Satellite symposium International Symposium on MPS San Diego, CA Aug. 2018
    Spinal Disease in MPS International Symposium on MPS San Diego, CA Aug. 2018
    Overview of Musculoskeletal Disease in MPS and ML International Symposium on MPS San Diego, CA Aug. 2018
    Early Diagnosis in the Mucopolysaccharidoses (MPS) Asia Pacific MPS Masterclass Taipei, Taiwan May 2018
    Bone Disease in MPS 14th International Symposium of the Portuguese Society for Metabolic Disorders, Porto, Portugal, March 2019 International Event
    Looking Beyond the X-Ray for Skeletal Dysplasia National Event: Pediatric Orthopedic Society of North America, November 2020
  • Grant Title Grantor Amount Award Date
    ACHieve: A multi-center, longitudinal, observational study of children with achondroplasia Ascendis, Inc. $153,900 Sept. 2019 - Sept. 2020
    An International, Prospective Registry Investigating the Natural History of Children with Achondroplasia Therachon, Inc $334,292 Sept. 2019 - Sept. 2020
    A Phase 3, Open-Label Long-Term Extension Study to Evaluate the Safety and Efficacy of BMN 111 in Children with Achondroplasia BioMarin Pharmaceutical Inc. $326,309 July 2019 - July 2024
    Are the ropivacaine plasma levels in children with lumbar plexus infusions below levels associated with toxicity? A preliminary study of steady state ropivacaine pharmacokinetics [PK] with a bolus dose and infusion Seattle Children’s Hospital, Academic Enrichment Fund $36,400 Sept. 2018
    X-linked Hypophosphatemia Disease Monitoring Program Ultragenyx $616,713 Sept. 2018 - May 2028
    A Multicenter, Multinational Clinical Assessment Study for Pediatric Patients with Achondroplasia BioMarin Pharmaceutical Inc. $310,586 Jan. 2017 - Jan. 2022
    Morquio A Registry Study (MARS) BioMarin Pharmaceutical Inc. $639,877 Sept. 2014 - Sept. 2024

Overview

Board Certification(s)

Orthopedic Surgery

Medical/Professional School

George Washington University School of Medicine and Health Sciences, Washington
University of Southern California, Los Angeles

Residency

Orthopedic Surgery, University of California San Diego, San Diego

Fellowship

Pediatric Orthopedics/Scoliosis, Texas Scottish Rite Hospital for Children, Dallas

Clinical Interests

Skeletal Dysplasia and Metabolic Bone Disease, Scoliosis and Spinal Deformity, Early Onset Scoliosis

Research Focus Area

Translational Research