Anne M. Lynn, MD


On staff since October 1981

Research Center: Center for Clinical and Translational Research

"Anesthesia administration can seem fairly anonymous, but helping a family and child through the procedures of anesthesia and surgery with the least amount of distress is very satisfying. There aren’t many specialties that tolerate singing as part of the job, either! I’ve spent part of my time studying safe perioperative pain relief with morphine or ketorolac, especially in infants. More recently, I’ve begun using acupuncture, which has the advantage of avoiding drug interactions. It’s very rewarding when infants or children respond to these treatments. I’ve also reached an age where I find personal satisfaction in teaching future anesthesiologists the clinical pearls of pediatric anesthesia."

  • Award Name Award Description Awarded By Award Date
    Myron Yaster Lifetime Achievement Award Society for Pediatric Anesthesia 2017
    Seattles Best Doctors Seattle Magazine 2015
    SEATTLE MAGAZINE TOP DOCTOR - 2014 Seattle Magazine 2014
    University of Washington Medicine Award for Excellence in Mentoring Women and Minorities University of Washington 2011
    The Best Doctors in America Listed in The Best Doctors in America 2008 - 2014
  • Manuscripts in Refereed Journals

    • McCann ME, Withington DE, Arnup SJ et al.
      Differences in Blood Pressure in Infants after General Anesthesia compared to awake Regional Anesthesia (GAS study – a prospective, randomized trial)
      Anesthesia & Analgesia, 2017 : 125837-845
    • Ralston-Wilson J, Artola, E, Lynn AM, Doorenbos AZ
      Feasibility of Developing an Inpatient Acupuncture Program at a Tertiary Care Pediatric Hospital
      J Altern Complement Med, 2016 : 22458-464
    • Davidson AJ, Disma N, de Graff JC et al. Lynn AM co-author
      Neurodevelopmental outcome at 2 years of age after general awake-regional anesthesia in infancy (GAS): an international, multicentre randomized controlled trial.
      Lancet, 2016 : 387239-250
    • Davidson AJ, Morton NS, Arnup SJ, et al. Lynn AM, GAS consortium participant
      Apnea after awake regional and general anesthesia in infants:The General Anesthesia compared to spinal anesthesia study – comparing apnea and neurodevelopmental outcomes, a randomized controlled trial
      Anesthesiology, 2015 : 12338-54
    • Frawley G, Bell G, Disma N, et al. Lynn AM GAS consortium participant
      Predictors of failure of awake regional anesthesia for neonatal hernia repair: Data from the general anesthesia compared to spinal anesthesia study – comparing apnea and neurodevelopmental outcomes
      Anesthesiology, 2015 : 12355-65
    • Gentry, K. R., McGinn, K., Kundu, A., Lynn, A
      Acupuncture therapy for infants: a preliminary report on reasons for consultation, feasibility and tolerability
      Ped Anesthesia, 2012 : 22690-695
    • Gentry K, Lynn AM, etc
      Enrollment Challenges in Multicenter International Studies: the example of the GAS Trial
      Pediatric Anesthesia, 2951-58
    • McCann ME, deGraff JC, Dorris L et al
      Neurodevelopmental Outcome at 5 years of age after general anesthesia or awake regional anesthesia in infancy (GAS): an international, multicenter, randomized controlled equivalence trial
    • Disma N, Wittington D, McCann ME, Hunt R, Arnup S, Izzo F, Morton N, Frawley G, Davidson A, Lynn A, Smzuk P, Thomas J, Ragg P, Pini Prato A
      Surgical Practice and Outcome in 711 neonates and infants undergoing hernia repair in a large multicenter RCT: secondary results from the GAS Study
      J Ped Surg , 531643-1650
    • Walco GA, Kopecky EA, Weisman SJ, Stinson J, Stevens B, Desjardins P, Berde CB, Krane EJ, Anand, KJS,Yaster M, Dampier CD, Gilron I, Lynn A, Maxwell L, McDermott M, Raja S, Schachtel B, Dworkin R, Turk D
      Clinical Study Designs and Models for Analgesic Medications for Acute Pain in Neonates, Infants, Toddlers, Children, and Adolescents: PedsACTTION Recommendations
      Pain , 159193-205

    Manuscripts Submitted

    • Jimenez, N., Anderson, G. D., Shen, D. D., Searles Nielsen, S., Farin, F. M., Lynn, A.
      Is ethnicity associated with opioids side effects in children? A study on morphine pharmacokinetics and clinical response among surgical patients
      Pediatric Anesthesia

    Other Publications

    • Martin LD, Jimenez, Lynn AM
      A Review of Perioperative Anesthesia and Analgesa for Infants: Updates and Trends to Watch
      F1000 Res review, 2017 Feb. 8 : 6120
    • Martin L, Jimenez N, Lynn AM
      Developmental Pharmacokinetics and Pharmacodynamics of Parenteral Opioid and NSAIDS in Neonates and Infants
      Colombiana de Anesthesiologica, 2017
    • Gentry K, Lynn A
      Congenital Anomalies and Syndromes Presenting in the Neonate
      Chapter in Neonatal Anesthesia, Cambridge University Press, 2017 : in press
    • Jimenez N, Lynn A
      Davis PJ (Ed.). Decision Support in Medicine, Anesthesiology, 2nd Ed., 2016
    • Walker K
      Jeune Syndrome
      Essence of Anesthesia Practice, 4th Ed. Elsevier, 2015
    • Lynn, A
      Commentary on Khalil study "Effect of IV ibuprofen in febrile pediatric patients"
      Anesthesiology News, 2014
    • Rowell J, Lynn AM, Filardi TZ, Celix J, Ojemann JG
      Acute unilateral enlargement of the parotid gland immediately post craniotomy in a pediatric patient: a case report.
      20512498 Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2010 Sept. : 1239-42
    • Jimenez N, Seidel K, Martin LD, Rivara FP, Lynn AM
      Perioperative analgesic treatment in Latino and non-Latino pediatric patients.
      20173265 Journal of health care for the poor and underserved, 2010 Feb. : 229-36
    • Anderson GD, Lynn AM
      Optimizing pediatric dosing: a developmental pharmacologic approach.
      19476420 Pharmacotherapy, 2009 June : 680-90
    • Lynn AM, Bradford H, Kantor ED, Seng KY, Salinger DH, Chen J, Ellenbogen RG, Vicini P, Anderson GD
      Postoperative ketorolac tromethamine use in infants aged 6-18 months: the effect on morphine usage, safety assessment, and stereo-specific pharmacokinetics.
      17456651 Anesthesia and analgesia, 2007 May : 1040-51, tables of contents
    • Piper NA, Flack SH, Loeser JD, Lynn AM
      Epidural analgesia in a patient with an intrathecal catheter and subcutaneous pump to deliver baclofen.
      16918665 Paediatric anaesthesia, 2006 Sept. : 989-92
    • Anand KJ, Aranda JV, Berde CB, Buckman S, Capparelli EV, Carlo W, Hummel P, Johnston CC, Lantos J, Tutag-Lehr V, Lynn AM, Maxwell LG, Oberlander TF, Raju TN, Soriano SG, Taddio A, Walco GA
      Summary proceedings from the neonatal pain-control group.
      16777824 Pediatrics, 2006 March : S9-S22
    • Jimenez N, Bradford H, Seidel KD, Sousa M, Lynn AM
      A comparison of a needle-free injection system for local anesthesia versus EMLA for intravenous catheter insertion in the pediatric patient.
      16428534 Anesthesia and analgesia, 2006 Feb. : 411-4
    • Berde CB, Jaksic T, Lynn AM, Maxwell LG, Soriano SG, Tibboel D
      Anesthesia and analgesia during and after surgery in neonates.
      16117991 Clinical therapeutics, 2005 June : 900-21
    • Anand KJ, Aranda JV, Berde CB, Buckman S, Capparelli EV, Carlo WA, Hummel P, Lantos J, Johnston CC, Lehr VT, Lynn AM, Maxwell LG, Oberlander TF, Raju TN, Soriano SG, Taddio A, Walco GA
      Analgesia and anesthesia for neonates: study design and ethical issues.
      16117988 Clinical therapeutics, 2005 June : 814-43
    • Lynn AM, Nespeca MK, Bratton SL, Shen DD
      Ventilatory effects of morphine infusions in cyanotic versus acyanotic infants after thoracotomy.
      12535033 Paediatric anaesthesia, 2003 Jan. : 12-7
    • Anne M. Lynn, MD, Flack, S., Piper, N. A
      Author's reply
      Pediatric Anesth, 7707
    • Martin L, Jimenez N, Lynn AM
      A Review of Perioperative Anesthesia and Analgesia for Infants: Updates and Trends to watch
      F1000Res, 6120

  • Presentations Title Event Location Date
    Panel member, Integrative Health Interventions – Acupuncture Seattle Children’s Hospital APP Retreat Seattle, WA May 11, 2018
    Acupuncture – How did I get here from there? Dept. Anesthesiology and Pain Medicine Grand Rounds, University of Washington Seattle, WA July 12, 2017
    Developmental Kinetics/dynamics of parenteral opioids and NSAIDS in neonates and infants Colombian Society of Anesthesiologists Annual Meeting June 2015
    Preparing for the Last 10 Years of Practice SPA Spring Meeting March 2015
    Clinical Competence Committees University of Washington, University of Washington Program Director Development series Seattle, WA Sept. 12, 2014
    Developmental Pharmacokinetics/Pharmacodynamics of Parenteral Opiates and NSAIDS in Infants:what are the Problems? Society for Pediatric Pain Management, SPPM First Annual Meeting Fort Lauderdale March 2014
    Evidence-based Management of Acute Intraoperative Emergencies in Children SPA Las Vegas, NV March 16, 2013
    Intensive Review of Pediatric Anesthesia Society for Pediatric Anesthesia Chicago, Il
  • Grant Title Grantor Amount Award Date
    ongoing funding to complete GAS study (general anesthesia versus spinal anesthesia in infants undergoing herniorraphy) Thrasher Foundation July 1, 2015 - June 30, 2018


Board Certification(s)

Pediatric Anesthesiology

Medical/Professional School

Stanford University School of Medicine, Stanford


Pediatrics, University of Washington, Seattle
Anesthesiology, University of Washington, Seattle


Pediatric Critical Care Medicine, Hospital for Sick Children, Toronto

Research Description

Morphine handling and its respiratory effects in infants were initial studies looking at patients having cardiac surgery and then infants having other major surgeries.

More recently, I've studied ketorolac a non-steriodal anti-inflammatory agent, in infants following major surgery. Now I'm beginning to study the use of acupuncture both for pain relief and more broadly its use for wellness following surgery or significant illness. Identifying which patients are most able to benefit from the use of acupuncture would be very useful since acupuncture treatments are quite labor intensive.

Research Focus Area