You may conduct research at Seattle Children’s that is reviewed by an external IRB. Seattle Children’s IRB has established processes in place with Western IRB (WIRB) and the NCI Pediatric Central IRB (PedCIRB), but you may designate any external IRB as the IRB of record for your study. For more information about submitting a study using an external IRB, refer to the Quick Guide – Submitting External IRB Studies (PDF).
Seattle Children's Research Institute has an agreement in place to allow for review by Western IRB (WIRB) of projects at a cost to study teams and/or sponsors. Below is the process needed for such review. Please contact the IRB office if you have questions about the forms or process.
NEW: The WIRB coversheet and consent form template have been updated. The consent form now integrates HIPAA language, so a separate HIPAA form is not required. Submissions to WIRB prior to July 17, 2017 will use the current forms. All submissions to WIRB on or after July 17, 2017 must use the updated forms.
- Use Click IRB to submit your Cover Sheet (DOC) with additional attachments, if applicable. Our office will review the request in Click and approve if Seattle Children’s agrees to rely upon WIRB for review. See the Quick Guide on the Click IRB Resources page entitled Submitting External IRB Studies (PDF) for more information.
- Upon approval to use WIRB, make your submission to WIRB using their application forms. Below, you will find a consent template that WIRB has approved for Seattle Children’s use.
Use these forms before July 17, 2017
Use these forms on or after July 17, 2017
WIRB charges review fees to sponsors and/or research teams. If the sponsor/site is participating in the Single Review Solution program, then the SRS pricing applies.
In accordance with the Seattle Children’s OHRP-approved FWA and the Authorization Agreement/Division of Responsibilities between the NCI Central IRB (CIRB) and Seattle Children’s, SCRI will rely on the CIRB Board for human subjects protections requirements for Seattle Children’s clinical trials that are opened via the CIRB independent model.
Other External IRBs
Please request a consultation for using external IRBs other than WIRB or NCI PedCIRB.