Mandatory Use of Click IRB

The IRB and Click Development Team are pleased to announce that all barriers to the universal use of the Click IRB system have been removed or mitigated. As of March 1, all work – new applications, modifications, renewals, etc. – will need to be submitted to the IRB via Click. Read more

Visit the Click IRB Resources page for the latest information about training, instructions on how to access Click IRB, and resources to assist you as you begin using the system, including printable Quick Guides and walkthrough videos. If you have questions or concerns, please email the IRB.

What is the Institutional Review Board?

The Institutional Review Board (IRB) is a committee established to protect the rights and welfare of the children and families who participate in research activities conducted under the auspices of Seattle Children's and affiliated research organizations. The IRB reports to the president of Seattle Children's Research Institute. The IRB is responsible for ensuring that basic ethical principles as well as federal regulations, state law and institutional policy governing the protection of research participants are applied to research activities.


IRB members are appointed by the president of the research institute. A broad representation of pediatric specialties is found among the scientific members. In addition to the scientific members, the IRB includes non-scientists and unaffiliated members as required by federal regulation.

Additional Information

  • Seattle Children's holds a Federalwide Assurance: FWA# 00002443.
  • Seattle Children's has two IRB registration numbers: IRB00000277 and IRB00009311.
  • View our institutional authority page (PDF).


Submit all study materials to the IRB via Click IRB.

Questions? Email the IRB staff or call 206-987-7804.