Condition or Therapy: Chronic nonbacterial osteomyelitis (CNO), chronic recurrent multifocal osteomyelitis (CRMO), juvenile idiopathic arthritis (JIA)
Category: Rheumatology

What is the goal of this study?

We want to see if thermal imaging, as well as ultrasound and MRI, can identify active arthritis and chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO) in patients.

Who can join the study?

This might be a good fit if your child: 

  • Is between 2 and 18 years old
  • Is getting an MRI for suspected CNO/CRMO; or
  • Has a flaring ankle or knee joint in clinic

What happens in the study?

If you choose to take part in this study, we would: 

  • Collect medical information from your child’s medical record.
  • Take images of you/your child’s extremities using a thermal imaging camera.
  • If you have CNO/CRMO, we would link the study visit to an existing MRI appointment.
  • If you have JIA, we would also conduct ultrasounds of your knees, ankles, elbows, and wrists.

Who can I contact for information or to enroll?

Email the research coordinator.


Study Location(s): Seattle Children's Hospital main campus
Principal Investigator: Dr. Yongdong (Dan) Zhao