Center for Immunity and Immunotherapies faculty and staff are solving some of the immune system's most complex problems.
The Center for Immunity and Immunotherapies (CIIT) at Seattle Children's Research Institute brings together a dynamic group of
across multiple disciplines to solve some of the immune system's most complex problems. Many of our researchers treat patients in the
other clinics at Seattle Children's Hospital. Our ultimate goal is to apply what we learn to advance the care of our patients.
Our research extends full-circle, rapidly evolving from clinical questions to laboratory-based investigation and back to patients in the form of
improved diagnostic tools
for primary immune deficiency and autoimmune diseases,
advanced therapies for genetic disorders
, innovative vaccine strategies and enhanced
Harnessing the Immune System's Healing Potential
We begin with the premise that a child's immune system has vast healing potential. We focus on harnessing that potential by manipulating the immune system to treat pediatric diseases, including immune deficiency, autoimmunity, allergies, organ transplant rejection, infections and cancer. As part of this work, we are improving the
molecular definition and diagnosis of immunological disorders
, developing disease-specific
cell therapies and stem cell transplantation
approaches, modulating immune function through small-molecule therapeutics and working to cure immune deficiencies through cutting-edge
gene therapy and gene repair
Working Collaboratively to Achieve Improved Health and Better Outcomes
David J. Rawlings, MD
Dr. David Rawlings
, director of the Center for Immunity and Immunotherapies, leads a distinguished group of experts who are searching for improved diagnostic tools for immune diseases and developing advanced therapies for genetic disorders. Our faculty also works closely with the members of the
University of Washington Department of Immunology
Because the challenges are exceedingly complex, we search broadly for answers. For example, we leverage the strengths of our investigators and the broad expertise of our collaborators within the
Northwest Genome Engineering Consortium (NGEC)
in Seattle, along with other prominent academic and biotech research groups here and around the world. We are
researchers who are leaders in the field - as well as graduate students, postdoctoral researchers and technicians with outstanding scientific talent - to join our thriving research community and complement our existing expertise by bringing new approaches, innovations and capabilities.
Above all, we are motivated by our patients' courage and are committed to helping them achieve improved health and better outcomes.
Read more about the center's