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Frenkel Lab

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Welcome to the Frenkel Lab

While pediatric HIV has been virtually eliminated in the U.S., hundreds of thousands of infants in the developing world acquire the infection each year. Led by Dr. Lisa Frenkel, the HIV Lab is working to bridge this gap through research focusing on:

  • Developing practical, affordable ways to prevent mother-infant HIV transmission
  • Identifying the mechanisms that cause adults to shed HIV in the genital tract, placing babies at risk of infection during birth
  • Understanding viral factors related to HIV transmission
  • Treating drug-resistant HIV in children and adults

Our research lab is also keenly interested in developing low-cost tests that can detect HIV, including drug-resistant strains, in infants, children and adults. For example, we have developed a test for drug-resistant HIV that uses only about $3 of supplies per test, plus technician's time. We are working toward implementations studies that make this test available in some African countries with the hope it will help doctors there provide appropriate treatments and better allocate resources.

Reflecting our projects, we are conducting collaborative studies with colleagues in Kenya, Peru, South Africa, Thailand, the U.S. and Zimbabwe, and in the past worked with researchers in India and Mozambique.

To learn more about the Frenkel Lab’s projects and publications, please visit our University of Washington website.

Investigator Biography

Dr. Lisa Frenkel

Dr. Lisa Frenkel is an internationally recognized expert on HIV and infectious disease. She is co-director of the Center for Global Infectious Disease Research at Seattle Children’s Research Institute; professor of pediatric infectious diseases, laboratory medicine and global health at the University of Washington; and co-director of Seattle Children’s pediatric infectious diseases and virology clinic.

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