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Center for Global Infectious Disease Research

The Center for Global Infectious Disease Research translates basic biology into new ways to diagnose, treat and prevent infectious diseases that impact children and adults worldwide. Learn more about the CGIDR.

Meet Us

Rose and Frenkel center leadership

Our Vision

We will use scientific discovery to understand, treat, prevent and cure infectious disease, developing solutions that help children grow into healthy adults.

Key Partnerships

Collaborations and partnerships are integral to the CGIDR’s approach. Our investigators work closely with colleagues at the University of Washington, Fred Hutchinson Cancer Research Center and other institutions.

Careers

Developing groundbreaking treatments takes more than just the right ideas. It also takes the right people – and the CGIDR is recruiting new members.

 

For information about potential opportunities, email us.

Latest News

  • New Study Helps Scientists Better Understand Why HIV Causes Lifelong Infection
    07.15.14 – Press Release
    HIV, the virus that causes AIDS, has the ability to integrate into the human genome, making it extremely difficult to cure the infection. A new study by scientists at Seattle Children’s Research Institute, the University of Washington and Fred Hutchinson Cancer Research Center found that when HIV integrates into genes involved with cancer, these cells tend to reproduce to a greater extent than other HIV-infected cells. According to study co-lead Dr. Thor Wagner, “This research brings us closer to understanding why HIV is such a long-lasting infection and may lead us to new avenues to cure HIV.”
  • HPV Research Could Decrease Cancer Risk for Millions
    06.25.14 – Seattle Children's On the Pulse
    The National Cancer Institute has awarded Seattle Children’s Research Institute adolescent medicine expert Dr. Rachel Katzenellenbogen more than $2 million to study what happens in the body between the time of human papillomavirus (HPV) infection and cancer development in search of opportunities to intervene and prevent malignant disease.
  • NIAID Awards $5.3 Million to Seattle Children’s Research Institute and Micronics Inc.
    04.15.14 – Press Release
    Tim Rose, PhD, co-director of the Center for Global Infectious Disease Research, in partnership with Micronics, Inc., has been awarded $5.3 million from the National Institute of Allergy and Infectious Diseases to develop a diagnostic tool and surveillance system that will identify and track influenza viruses.

Publications

Lack of resistance to integrase inhibitors among antiretroviral-naive subjects with primary HIV-1 infection, 2007-2013. Stekler JD, McKernan J, Milne R, Tapia KA, Mykhalchenko K, Holte S, Maenza J, Stevens CE, Buskin SE, Mullins JI, Frenkel LM, Collier AC. Antivir Ther. 2014 May 15. doi: 10.3851/IMP2780

 

Pediatric Infection and Intestinal Carriage due to Extended Spectrum Cephalosporin-Resistant Enterobacteriaceae. Zerr DM, Qin X, Oron AP, Adler AL, Wolter DJ, Berry JE, Hoffman L, Weissman SJ. Antimicrob Agents Chemother. 2014 May 5.

 

KSHV cell attachment sites revealed by ultra sensitive tyramide signal amplification (TSA) localize to membrane microdomains that are up-regulated on mitotic cells. Garrigues HJ, Rubinchikova YE, Rose TM. Virology. 2014 Mar;452-453:75-85. doi: 10.1016/j.virol.2014.01.006.

 

Group B streptococcal infection of the choriodecidua induces dysfunction of the cytokeratin network in amniotic epithelium: a pathway to membrane weakening. Vanderhoeven JP, Bierle CJ, Kapur RP, McAdams RM, Beyer RP, Bammler TK, Farin FM, Bansal A, Spencer M, Deng M, Gravett MG, Rubens CE, Rajagopal L, Adams Waldorf KM. PLoS Pathog. 2014 Mar 6;10(3):e1003920.

 

NFX1-123 and human papillomavirus 16E6 increase Notch expression in keratinocytes. Vliet-Gregg PA, Hamilton JR, Katzenellenbogen RA. J Virol. 2013 Dec;87(24):13741-50. doi: 10.1128/JVI.02582-13.

 

Ets-1 is required for the activation of VEGFR3 during latent Kaposi's sarcoma-associated herpesvirus infection of endothelial cells. Gutierrez KD, Morris VA, Wu D, Barcy S, Lagunoff M. J Virol. 2013 Jun;87(12):6758-68. doi: 10.1128/JVI.03241-12.

Contact Us

 

Email the CGIDR

206-884-3573

 

Address:

1900 Ninth Avenue

Seattle, WA 98101

 

Mailing Address:

1900 Ninth Avenue

M/S JMB-8

PO Box 5371

Seattle, WA 98145-5005

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