The Center for Developmental Biology and Regenerative Medicine (CDBRM) studies the body's response to injury at multiple levels, including molecular, cellular, tissue and whole-organ. CDBRM uses the Beier lab's research to develop therapeutic interventions that will ultimately help the body repair itself.
The Beier lab studies organ development and repair using genetic and genomic analysis of model systems and human birth defect syndromes.
investigates the genetic contributions - including their interplay with nutritional and teratogenic environmental factors - to the presentation of cleft lip and palate, midface hypoplasia and other common craniofacial disorders.
studies the fundamental mechanisms behind craniosynostosis and other malformations to improve care for patients with craniofacial conditions.
investigates the genetic causes of craniofacial disorders to improve the diagnosis and management of infants, children and adolescents with craniofacial and genetic conditions.
studies the genetics and epidemiology of craniofacial malformations to identify their causes and develop research methods that can be used to study a wide variety of birth defects.
investigates the contributions of genetic and environmental factors responsible for human malformations, specifically craniofacial disorders and normal phenotypic variation. The lab is currently unraveling the epigenetic changes - alternations in the genome due to environmental factors as opposed to mutations - that contribute to fetal alcohol spectrum disorders.
uses molecular, biological and developmental genetic approaches to address fundamental questions in the development and differentiation of blood vessels. The goal is to understand the molecular mechanisms involved in the embryonic development of the heart and vascular system to discover and develop applications for stem and progenitor cell-based therapies.
investigates how heart and muscle cells develop in the hope of uncovering new treatments for muscular dystrophy and heart disorders.