MicroCT imaging of vasculature in adult mouse heart

MicroCT imaging of vasculature in adult mouse heart

SANTA offers tomographic capabilities (in vivo and ex vivo microCT and optical projection tomography [OPT]) to members of Seattle Children's and the University of Washington, as well as external researchers, on an affordable, fee-for-service basis.

State-of-the-Art Imaging

MicroCT imaging of a craniofacial abnormality in a mouse

MicroCT imaging of a craniofacial abnormality in a mouse

Tomographic imaging offers qualitative and quantitative analysis of biological and non-biological samples in two, three and four dimensions. Tomographic imaging provides resolutions much greater than magnetic resonance imaging (MRI) and on much larger samples than used in confocal microscopy. Importantly, tomographic imaging is non-destructive, leaving all samples intact so they can be used in other lab procedures such as histology or confocal analyses.

OPT imaging of vasculature in mouse embryo

OPT imaging of vasculature in mouse embryo

SANTA was created to meet a growing need for a precise assessment of phenotypes in small animals used to better understand the basis of human craniofacial malformations. The high resolution of these imaging modalities can be exploited to investigate the impact of individual genes or environmental factors and can be utilized in many other biomedical and clinical research fields - including dentistry, bioengineering and trauma medicine - that use small-animal research to better understand disease and tissue repair.

The facility's scanners can also be used for imaging of non-biological hard materials such as electrical components, as well as geological and paleontological specimens.

History

OPT imaging of internal anatomy of chick embryo

OPT imaging of internal anatomy of chick embryo

SANTA was established in 2008 with the generous support of the Murdock Charitable Trust and Seattle Children's through an award to Drs. Timothy Cox, Michael Cunningham and Richard Hopper of Children's Craniofacial Center.

Location and Fees

SANTA is located in the Center for Developmental Biology and Regenerative Medicine at Seattle Children's Research Institute ( Jack R. MacDonald Building, corner of Ninth Avenue and Stewart Street).

See the facility's current rates (PDF), also available on the forms page.

Contact

Please direct inquiries to SANTA staff via email. We will follow up by phone or email as soon as possible, usually within 24 hours.