Seattle Children’s Research Institute houses a number of core laboratories and services. These cores provide our scientists access to state-of-the-art instrumentation and technical services.
Cores are administered through a centralized department responsible for ensuring that services are affordable, convenient and efficient.
- Children's Core for Biomedical Statistics
Serves as the primary statistical design and data analysis core for Seattle Children’s Research Institute research activities. Formerly the Office of Biostatistical Services.
- Clinical Research Staff Support Core
Assists with the organization, implementation and completion of clinical research studies.
- Cystic Fibrosis Isolate Core
Provides CF bacterial isolates to researchers at the University of Washington and other academic institutions.
- Flow Cytometry Core
Provides diverse flow-cytometric applications for characterization and purification of cells from mixed-cell suspensions, as well as consulting services.
- High-Throughput Data Analysis Core
Provides state-of-the-art, specialized analyses for high-throughput data sets (including data generated by proteomic, genomic, microarray/transcriptomic and metabolomics studies) and consultation on experimental design.
- Immunology Diagnostic Laboratory: A Jeffrey Modell Diagnostic Center
Performs genetic testing, flow cytometry and cellular immunology studies to diagnose and monitor immunologic disorders.
- Investigational Drug Service
Dispenses medications used in Seattle Children’s inpatient and ambulatory clinical trials.
- Luminex Core
Provides access to a Luminex 200 instrument and expertise in bioassays development and analysis.
- Next Generation Sequencing Core
Provides access to next generation sequencing technology based in the laboratory of Sihoun Hahn, MD, PhD.
- NGEC Cell and Virus Core Facility
Centralizes the specialized knowledge and equipment required for cell separation and analysis and NIL vector production activities.
- Pathology Integrative Resource Core (PIRC)
The Pathology Integrative Resource Core (PIRC) provides an array of pathology-related services to support basic, clinical and translational research at Seattle Children’s. Core personnel provide a broad range of expertise in histology, tissue microarrays, photography support, DNA and RNA isolation, electron microscopy, specimen banking and other comparative pathology services.
- Pediatric Clinical Research Center
This multidisciplinary facility provides an environment for the conduct of clinical research encompassing a broad spectrum of human pathophysiology and disease.
- Radiology Clinical Research Imaging Core (RCRIC)
Provides assistance to investigators and research staff to facilitate the selection, set-up, implementation and conduct of research studies involving Seattle Children’s radiology imaging across its multiple modalities.
- Small Animal Tomographic Analysis Facility (SANTA)
Offers tomographic capabilities (in vivo and ex vivo microCT and optical projection tomography [OPT]) to members of Seattle Children’s and the University of Washington, as well as external researchers, on an affordable, fee-for-service basis.
- Viral Core
Supports the construction and production of lentiviral vectors, including non-integrating lentiviral vectors.