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Core Services

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Seattle Children’s Research Institute houses a number of core laboratories and services. These cores provide our scientists access to state-of-the-art instrumentation and technical services.

Cores are administered through a centralized department responsible for ensuring that services are affordable, convenient and efficient.

  • Acti-Core
    Provides support services for the use of actigraphy. Currently supports actigraphy needs in the Center for Child Health, Behavior and Development and the Center for Clinical and Translational Research.
  • Biostatistics, Epidemiology, Econometrics and Programming (BEEP) Core
    Serves the Center for Child Health, Behavior and Development's technical needs in a cost-effective manner, especially in the areas of statistical analysis, data management, surveys, web development and graphic design.
  • Children's Core for Biomedical Statistics
    Serves as the primary statistical design and data analysis core for Seattle Children’s Research Institute research activities. Formerly the Office of Biostatistical Services.
  • Clinical Research Staff Support Core
    Assists with the organization, implementation and completion of clinical research studies.
  • Cystic Fibrosis Isolate Core
    Provides CF bacterial isolates to researchers at the University of Washington and other academic institutions.
  • Flow Cytometry Core
    Provides diverse flow-cytometric applications for characterization and purification of cells from mixed-cell suspensions, as well as consulting services.
  • High-Throughput Data Analysis Core
    Provides state-of-the-art, specialized analyses for high-throughput data sets (including data generated by proteomic, genomic, microarray/transcriptomic and metabolomics studies) and consultation on experimental design.
  • Immunology Diagnostic Laboratory: A Jeffrey Modell Diagnostic Center
    Performs genetic testing, flow cytometry and cellular immunology studies to diagnose and monitor immunologic disorders.
  • Investigational Drug Service
    Dispenses medications used in Seattle Children’s inpatient and ambulatory clinical trials.
  • Luminex Core
    Provides access to a Luminex 200 instrument and expertise in bioassays development and analysis.
  • Next Generation Sequencing Core
    Provides access to next-generation sequencing technology based in the laboratory of Sihoun Hahn, MD, PhD.
  • NGEC Cell and Virus Core Facility
    Centralizes the specialized knowledge and equipment required for cell separation and analysis and NIL vector production activities.
  • Pathology Integrative Resource Core (PIRC)
    The Pathology Integrative Resource Core (PIRC) provides an array of pathology-related services to support basic, clinical and translational research at Seattle Children’s. Core personnel provide a broad range of expertise in histology, tissue microarrays, photography support, DNA and RNA isolation, electron microscopy, specimen banking and other comparative pathology services.
  • Pediatric Clinical Research Center
    This multidisciplinary facility provides an environment for the conduct of clinical research encompassing a broad spectrum of human pathophysiology and disease.
  • Radiology Clinical Research Imaging Core (RCRIC)
    Provides assistance to investigators and research staff to facilitate the selection, set-up, implementation and conduct of research studies involving Seattle Children’s radiology imaging across its multiple modalities.
  • Small Animal Tomographic Analysis Facility (SANTA)
    Offers tomographic capabilities (in vivo and ex vivo microCT and optical projection tomography [OPT]) to members of Seattle Children’s and the University of Washington, as well as external researchers, on an affordable, fee-for-service basis.
  • Therapeutic Cell Production Core
    Helps researchers navigate the process of adapting research laboratory methods to a manufacturing environment, including required release testing, final product characterization and regulatory support.
  • Viral Core
    Supports the construction and production of lentiviral vectors, including non-integrating lentiviral vectors.

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