Seattle Children's Research Institute houses a number of core laboratories and services. These cores provide our scientists access to state-of-the-art instrumentation and technical services.
Cores are administered through a centralized department responsible for ensuring that services are affordable, convenient and efficient.
Provides support services for the use of actigraphy. Currently supports actigraphy needs in the Center for Child Health, Behavior and Development and the Center for Clinical and Translational Research.
- Biostatistics, Epidemiology, Econometrics and Programming (BEEP) Core
Serves the Center for Child Health, Behavior and Development's technical needs in a cost-effective manner, especially in the areas of statistical analysis, data management, surveys, web development and graphic design.
- Children's Core for Biomedical Statistics
Serves as the primary statistical design and data analysis core for Seattle Children's Research Institute research activities. Formerly the Office of Biostatistical Services.
- Clinical Research Staff Support Core
Assists with the organization, implementation and completion of clinical research studies.
- Cystic Fibrosis Isolate Core
Provides CF bacterial isolates to researchers at the University of Washington and other academic institutions.
- Flow Cytometry Core
Provides diverse flow-cytometric applications for characterization and purification of cells from mixed-cell suspensions, as well as consulting services.
- High-Throughput Data Analysis Core
Provides state-of-the-art, specialized analyses for high-throughput data sets (including data generated by proteomic, genomic, microarray/transcriptomic and metabolomics studies) and consultation on experimental design.
- Immunology Diagnostic Laboratory: A Jeffrey Modell Diagnostic Center
Performs genetic testing, flow cytometry and cellular immunology studies to diagnose and monitor immunologic disorders.
- Investigational Drug Service
Dispenses medications used in Seattle Children's inpatient and ambulatory clinical trials.
- Next Generation Sequencing Core
Provides access to next-generation sequencing technology based in the laboratory of Sihoun Hahn, MD, PhD.
- NGEC Cell and Virus Core Facility
Centralizes the specialized knowledge and equipment required for cell separation and analysis and NIL vector production activities.
- Pathology Integrative Resource Core (PIRC)
The Pathology Integrative Resource Core (PIRC) provides an array of pathology-related services to support basic, clinical and translational research at Seattle Children's. Core personnel provide a broad range of expertise in histology, tissue microarrays, photography support, DNA and RNA isolation, electron microscopy, specimen banking and other comparative pathology services.
- Pediatric Clinical Research Center
This multidisciplinary facility provides an environment for the conduct of clinical research encompassing a broad spectrum of human pathophysiology and disease.
- Radiology Clinical Research Imaging Core (RCRIC)
Provides assistance to investigators and research staff to facilitate the selection, set-up, implementation and conduct of research studies involving Seattle Children's radiology imaging across its multiple modalities.
- Small Animal Tomographic Analysis Facility (SANTA)
Offers tomographic capabilities (in vivo and ex vivo microCT and optical projection tomography [OPT]) to members of Seattle Children's and the University of Washington, as well as external researchers, on an affordable, fee-for-service basis.
- Therapeutic Cell Production Core
Helps researchers navigate the process of adapting research laboratory methods to a manufacturing environment, including required release testing, final product characterization and regulatory support.
- Viral Core
Supports the construction and production of lentiviral vectors, including non-integrating lentiviral vectors.