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Cystic Fibrosis Research

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CF research

From developing groundbreaking therapies to leading clinical trials, Children’s has been an international leader in cystic fibrosis (CF) research for more than 25 years.

Our dedicated team of clinical researchers, laboratory scientists and staff is committed to improving the quality of life for people with CF of all ages. Through our successful research program, we are learning more about the disease, testing new therapies and developing novel measures of improved health outcomes.

At any given time, there is a wide variety of CF clinical trials being conducted at Children’s. These include:

  • Interventional studies designed to test the safety and effectiveness of a wide range of new treatments, such as inhaled antibiotics to drugs that target the primary defect in CF.
  • Observational studies, which contribute to our understanding of CF and the effect of various factors on health and wellness – for example, risk factors for bacterial infection or the association between genetic factors and illness.
  • Outcome measure studies to improve our ability to accurately assess the effects of new treatments – for example, improved detection of pulmonary function changes in infants or tools for home monitoring of patient symptoms.

See what research studies we have going on and are open for participation.

Make a Difference: Take Part in a Clinical Trial

child on blue couch

CF is one of the most common chronic lung diseases in children and young adults. Most children with CF are diagnosed by age 2; however, some are not diagnosed until age 18 or older.

Clinical trials are imperative in the battle against CF and our understanding of the disease. However, they can’t take place unless people with CF volunteer to take part. If you or a child you know is interested in participating in a clinical trial, please speak with your CF physician or contact one of our research coordinators.

Patient story

Read Changing Childhoods: Cystic Fibrosis Research Makes a Difference for Molly.

Affiliated Research Programs

Our team works closely with their colleagues at the University of Washington, as well as across the country and around the world. Visit our Affiliated Programs page to learn about the groups and programs we are associated with.

Learn More About CF Research

To learn more about the importance of participating in CF clinical trials, the types of therapies being developed and clinical trials taking place around the country, see the clinical trials section on the Cystic Fibrosis Foundation website and the NIH Children and Clinical Trials website.

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