Center for Clinical and Translational Research

The Center for Clinical and Translational Research (CCTR) plays an integral role in transforming scientific discoveries into real-world therapies that prevent and treat childhood illness and improve the quality of children’s daily lives. Learn more about the CCTR.

Programs and Resources for Researchers

CCTR’s programs, facilities and services help ensure researchers within the center – and throughout Children’s – have the means and the opportunity to conduct safe, efficient, and ethical research involving children.

Featured Research

  • Dietary Therapy for IBD

    New research demonstrates that the Specific Carbohydrate Diet can induce clinical remission in ulcerative colitis and Crohn's disease.

  • Promoting Resilience; Reducing Stress

    A promising intervention gives teens and young adults coping skills to manage stress after a diagnosis and boost quality of life beyond treatment.

Stay Informed



Help us answer questions about childhood health and illness, and help other children in the future. See a list of our current research studies.

In the News

  • Bonnie Ramsey Receives the Warren Alpert Foundation Prize
    Congratulations to Dr. Bonnie Ramsey, honored by the Warren Alpert Foundation for her transformative discoveries in pulmonology that led to the development of new life-altering treatments for those with cystic fibrosis. The Warren Alpert Foundation, in association with Harvard Medical School, honors trailblazing scientists whose work has improved the understanding, prevention, treatment or cure of human disease. Bonnie, along with the other four honorees, will be recognized at a symposium on Oct. 4 at Harvard Medical School. Read more.
  • One family's story of hardships, triumphs with son who has rare craniofacial disorder
    11.16.17 – ABC News

    Russel and Magda Newman’s son, Nathaniel, was diagnosed with Treacher Collins, an extremely rare congenital craniofacial disorder caused by mutations in the POLR1C gene. When Nathaniel was 12 years old, the Newmans met with surgeons at Seattle Children's Hospital and made the difficult decision to have him undergo a radical surgery that had only been performed on one other child with Treacher Collins. The goal of the surgery was to be able to open up Nathaniel’s airway enough to finally remove his trach. For the surgery, Dr. Richard Hopper, the chief surgeon at the hospital’s craniofacial center, had to literally rearrange the bones in Nathaniel’s face.
  • New blood pressure guidelines for children
    10.09.17 – The New York Times
    In August, the American Academy of Pediatrics published a report updating its guidelines for screening and managing high blood pressure in youngsters. The report includes a much-simplified chart to help practicing physicians readily determine whether a child’s blood pressure is within normal parameters. Because high blood pressure often runs in families, detecting it in a child may prompt a check of the parents and other family members and end up saving their health and lives, said Dr. Joseph Flynn, chief of pediatric nephrology at Seattle Children’s Hospital and lead author of the new guidelines.