Center for Clinical and Translational Research

The Center for Clinical and Translational Research (CCTR) plays an integral role in transforming scientific discoveries into real-world therapies that prevent and treat childhood illness and improve the quality of children’s daily lives. More about the CCTR.

Meet Us

Programs and Resources for Researchers

CCTR’s programs, facilities and services help ensure researchers within the center — and throughout Seattle Children’s — have the means and the opportunity to conduct safe, efficient, and ethical research involving children.

Funding and Educational Programs

Featured Research

Are New Meds Safer?
Dr. Jack McClellan examines the usefulness and safety of commonly prescribed antipsychotic medications.
Sperm Banking: A New Frontier
Dr. Margarett Shnorhavorian and her team are helping preserve the fertility potential of young boys who are undergoing treatment – such as therapies for cancer and hematologic disorders – that could leave them sterile.

Improving Pain Management
Dr. Gary Walco is on a mission to make every child’s experience at the hospital as painless as possible. Starting now.
Defending the Body Against Viruses
As a national authority on influenza and children, Dr. Janet Englund is leading clinical studies on how differences in the way we give pediatric flu vaccinations may affect outcomes.

Participate in Research

Participants in clinical studies can play a more active role in their own health care, gain access to new research treatments before they are widely available, and help others by contributing to medical research.

Read more about clinical studies in children and ask your doctor or nurse about studies at Children’s that might be right for you or your child.

Key Partnerships

Partnerships are a key part of the CCTR mission. Our researchers collaborate with their colleagues at Seattle Children’s, across the nation, and around the world in pursuit of innovative health solutions.

CCTR is the pediatric home of the Institute of Translational Health Sciences, and we partner regularly with the University of Washington and Fred Hutchinson Cancer Research Center.

Publications

Improving childhood vaccination rates. N Engl J Med. 2012 Feb 2;366(5):391-3. Diekema DS.
A CFTR potentiator in patients with cystic fibrosis and the G551D mutation. N Engl J Med. 2011 Nov 3;365(18):1663-72. Ramsey BW, Davies J, McElvaney NG, Tullis E, Bell SC, Dřevínek P, Griese M, McKone EF, Wainwright CE, Konstan MW, Moss R, Ratjen F, Sermet-Gaudelus I, Rowe SM, Dong Q, Rodriguez S, Yen K, Ordoñez C, Elborn JS; VX08-770-102 Study Group.
A Randomized Clinical Trial Comparing Oral, Aerosolized Intranasal, and Aerosolized Buccal Midazolam. Ann Emerg Med. 2011 Oct;58(4):323-329. Klein EJ, Brown JC, Kobayashi A, Osincup D, Seidel K.
EXT2 positive multiple hereditary osteochondromas with some features suggestive of metachondromatosis. Skeletal Radiology 2011 Sep 4. Vinning NC, Done S, Glass IA, Parnell SE, Sternen DL, Leppig KA, Mosca VS, Goldberg MJ.

Stay Informed

Download the latest edition of CCTR News (PDF).
UW Faculty Development Days – February 28
CCTR Clinical Research Scholars Program – applications due April 1
CCTR Science Day (PDF) – May 10
Abstract submissions (DOC) due March 18

Our Experts in the Media

Vertex’s Big Day Felt Like Moon Landing, Seattle Researcher Says
02.01.2012 – Xconomy
Bonnie Ramsey, MD said three years ago that a cystic fibrosis drug from Vertex Pharmaceuticals was a huge medical advance in the making. Yesterday, she says, was the day it truly felt like she was part of a team that reached the moon-shot goal. The good news came when the FDA approved Vertex’s ivacaftor (Kalydeco) as the first drug of its kind to work by treating an underlying genetic defect for cystic fibrosis.
Cheap Ways to Teach Kids a Healthy Lifestyle
1.13.2012 – FOX Business
With childhood obesity, diabetes and high blood pressure on the rise in our society, it’s more important than ever for parents to take responsibility early on for getting their youngsters on the right track for good health. “It’s a gift to give children time to play, be active and have fun,” says Dr. Mollie Grow.
Which vaccines doctors advise parents not to put off
11.29.2011 – KING 5 TV
According to a new study from Seattle Children's Research Institute, 77% of pediatricians in Washington state are being asked by patients to use an alternative vaccine schedule. Seattle Children’s Dr. Doug Opel discusses the study findings.

Careers

Developing innovative treatments to potentially prevent and cure childhood illnesses takes more than just the right ideas. It also takes the right people. We are constantly seeking experienced leaders and enthusiastic emerging professionals who embrace collaboration and are committed to improving child health.

Does that sound like you? Please visit the Seattle Children's Careers page to find your perfect career in the CCTR.

Contact Us

Email CCTR

206-884-7469

2001 Eighth Ave, Suite 400

Mailstop: CW8-5B

Seattle, WA 98121

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Donate to Research

More than half of the kids who come to Seattle Children’s live with serious conditions that they will have for the rest of their lives. Research can give them a different future. Your support makes it possible.

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